Dharmendra Bhadauria
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View article: Anemia of Chronic Kidney Disease in India: Consensus Guidelines of Indian Society of Nephrology
Anemia of Chronic Kidney Disease in India: Consensus Guidelines of Indian Society of Nephrology Open
Anemia is common in patients with CKD and ESKD, with a 50% prevalence in the USA and higher in India. The overall prevalence of anemia in CKD is twice the general population, increasing with CKD progression. The last guidelines for anemia …
View article: Non-Invasive Prediction Tool for Non-Diabetic Kidney Diseases in Patients with Type-2 Diabetes Mellitus
Non-Invasive Prediction Tool for Non-Diabetic Kidney Diseases in Patients with Type-2 Diabetes Mellitus Open
Background Despite being the gold standard in detecting non-diabetic kidney diseases (NDKD) in Type-2 Diabetes Mellitus (T2DM), renal biopsy poses an inherent risk of life-threatening complications. The current study aims to develop and va…
View article: Oral iptacopan therapy in patients with C3 glomerulopathy: a randomised, double-blind, parallel group, multicentre, placebo-controlled, phase 3 study
Oral iptacopan therapy in patients with C3 glomerulopathy: a randomised, double-blind, parallel group, multicentre, placebo-controlled, phase 3 study Open
Novartis Pharma.
View article: Interventions Related to Takayasu Arteritis, their Clinical and Angiographic Associations, and Prognostic Relevance - A Cohort Study
Interventions Related to Takayasu Arteritis, their Clinical and Angiographic Associations, and Prognostic Relevance - A Cohort Study Open
About one-sixth of our cohort of TAK had undergone interventions, most often endovascular interventions. One-fourth required multiple interventions. Survival was similar in TAK with or without interventions.
View article: Insights into Diabetes Muscle Infarction: Clinical Characteristics and Outcome
Insights into Diabetes Muscle Infarction: Clinical Characteristics and Outcome Open
Background: Diabetes muscle infarction (DMI) is a common misdiagnosed and under-reported diabetes complication. This causes a delay in diagnosis, which increases the morbidity of the disease. Objective: To review all cases of DMI and its p…
View article: Randomized Double-Blind Placebo-Controlled Trial of Desmopressin for Post–Kidney Biopsy Bleeding
Randomized Double-Blind Placebo-Controlled Trial of Desmopressin for Post–Kidney Biopsy Bleeding Open
Desmopressin effectively reduces postbiopsy bleeding and hematoma formation with manageable side effects, supporting its role as a prophylactic option in kidney biopsies. Further studies are needed to confirm its broader clinical applicati…
View article: A Comprehensive Look at Focal Segmental Glomerulosclerosis Recurrence in Adult Transplant Patients: Findings from a Single Institution with Review of Literature
A Comprehensive Look at Focal Segmental Glomerulosclerosis Recurrence in Adult Transplant Patients: Findings from a Single Institution with Review of Literature Open
Background: Focal segmental glomerulosclerosis (FSGS) is a kidney disease with diverse causes, classified as primary, genetic, or secondary. There is a high recurrence rate of FSGS posttransplant and is associated with a significant risk o…
View article: Role of multi-parametric ultrasonography for the assessment and monitoring of functional status of renal allografts with histopathological correlation
Role of multi-parametric ultrasonography for the assessment and monitoring of functional status of renal allografts with histopathological correlation Open
BACKGROUND The study focuses on the use of multi-parametric ultrasound [gray scale, color Doppler and shear wave elastography (SWE)] to differentiate stable renal allografts from acute graft dysfunction and to assess time-dependent changes…
View article: Prevalence of Human Leukocyte Antigen Alleles Polymorphism in North Indian Population
Prevalence of Human Leukocyte Antigen Alleles Polymorphism in North Indian Population Open
Background Human leukocyte antigens (HLA) are highly polymorphic glycoproteins required for immune response and recognizing self or non-self. Knowing the HLA diversity in a population may be helpful in the selection of organ allocation for…
View article: Long-Term Outcomes of Anticomplement Factor H Antibody Positive Versus Negative Atypical Hemolytic Uremic Syndrome
Long-Term Outcomes of Anticomplement Factor H Antibody Positive Versus Negative Atypical Hemolytic Uremic Syndrome Open
Background Atypical hemolytic uremic syndrome (aHUS) is a severe thrombotic microangiopathy predominantly affecting the kidneys, often associated with complement dysregulation. This study is aimed to analyze the clinical characteristics, t…
View article: Novel mutation patterns in children with steroid-resistant nephrotic syndrome
Novel mutation patterns in children with steroid-resistant nephrotic syndrome Open
Background Idiopathic nephrotic syndrome (NS) in children poses treatment challenges, with a subset developing steroid-resistant nephrotic syndrome (SRNS). Genetic factors play a role, yet data on paediatric SRNS genetics in India are scar…
View article: Prevalence, Predictors, and Prognosis of Serious Infections in Takayasu Arteritis: A Cohort Study
Prevalence, Predictors, and Prognosis of Serious Infections in Takayasu Arteritis: A Cohort Study Open
Objective To describe the incidence, risk factors, and outcomes associated with serious infections in patients with Takayasu arteritis (TA). Methods Serious infections, defined as infections resulting in hospitalization or death or unusual…
View article: WCN24-1592 CLINICAL PROFILE, OUTCOMES AND ROLE OF STEROIDS IN ACUTE INTERSTITIAL NEPHRITIS : A SINGLE CENTRE EXPERIENCE OF 10 YEARS FROM INDIA
WCN24-1592 CLINICAL PROFILE, OUTCOMES AND ROLE OF STEROIDS IN ACUTE INTERSTITIAL NEPHRITIS : A SINGLE CENTRE EXPERIENCE OF 10 YEARS FROM INDIA Open
Acute interstitial nephritis (AIN) is one of the major causes of Acute kidney injury who mainly present with non-oliguria. It is imperative to have tissue diagnosis of AIN in order to decide on therapy in cases who are not showing self-rec…
View article: WCN24-2434 SIGNIFICANCE OF COEXISTENT NON-DIABETIC RENAL PATHOLOGY IN TYPE II DIABETIC KIDNEY DISEASE PATIENTS ON RENAL BIOPSY
WCN24-2434 SIGNIFICANCE OF COEXISTENT NON-DIABETIC RENAL PATHOLOGY IN TYPE II DIABETIC KIDNEY DISEASE PATIENTS ON RENAL BIOPSY Open
Diabetic kidney disease (DKD) is world over one of the leading causes of chronic kidney disease. The presence of coexistent non-diabetic renal pathology (CNDRP) with DKD may complicate already undergoing DKD leading to faster decline in re…
View article: The Unusual Adverse Effects of Antituberculosis Therapy in Kidney Patients
The Unusual Adverse Effects of Antituberculosis Therapy in Kidney Patients Open
Background: Chronic kidney disease (CKD) patients are at a high risk of tuberculosis (TB), with a relative risk of developing active TB of 10%–25%. Similarly, glomerular disease increases the risk of TB due to diminished glomerular filtrat…
View article: WCN24-1051 CLINICAL PROFILE, DIAGNOSIS,THERAPEUTIC INTERVENTION AND COMPLICATIONS IN RENAL BIOPSY IN CKD POPULATION – SINGLE CENTER 20 YEARS’ EXPERIENCE
WCN24-1051 CLINICAL PROFILE, DIAGNOSIS,THERAPEUTIC INTERVENTION AND COMPLICATIONS IN RENAL BIOPSY IN CKD POPULATION – SINGLE CENTER 20 YEARS’ EXPERIENCE Open
Clinicians avoid biopsy in Chronic Kidney Disease (CKD) as there is high risk of bleed. However there are conditions where benefits outweigh risks like ascertaining cause of CKD in patients going for transplant and in those where reversibi…
View article: WCN24-2056 INFLUENCE OF INITIAL CATHETER RELATED AND MECHANICAL COMPLICATIONS ON PERITONITIS AND CATHETER SURVIVAL OF CAPD PATIENTS
WCN24-2056 INFLUENCE OF INITIAL CATHETER RELATED AND MECHANICAL COMPLICATIONS ON PERITONITIS AND CATHETER SURVIVAL OF CAPD PATIENTS Open
Continuous ambulatory peritonral dialysis (CAPD) is a well-established mode of renal replacement therapy in India. However, complications related to peritoneal dialysis catheter and other mechanical complications have hampered its success.…
View article: Urinary Mitochondrial DNA Induces an Inflammatory Response in Peripheral Blood Mononuclear Cells
Urinary Mitochondrial DNA Induces an Inflammatory Response in Peripheral Blood Mononuclear Cells Open
Background: Mitochondria are semiautonomous cell organelles having its own nucleic acid. Mitochondrial DNA (Mt-DNA) remain in hypomethylated (CpG) state and impose an immunogenic response by binding to the toll-like receptor (TLR-9) throug…
View article: WCN24-1000 OUTCOMES OF ATYPICAL HEMOLYTIC UREMIC SYNDROME
WCN24-1000 OUTCOMES OF ATYPICAL HEMOLYTIC UREMIC SYNDROME Open
Atypical haemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy that primarily affects the kidneys and multiple organs. While conventional immunosuppression ( Corticosteroids and Mycophenolate Mofetil) and plasma exchange are av…
View article: Renal Transplantation in Rare Monogenic Urinary Stone Disease – A Single-center Experience
Renal Transplantation in Rare Monogenic Urinary Stone Disease – A Single-center Experience Open
Introduction: Monogenic urinary stone disease (MUSD) tends to be more severe with early onset of symptoms and a higher risk of chronic kidney disease than sporadic USD. The literature on the outcome after renal transplant in patients with …
View article: The Spectrum of Ocular Manifestations among Renal Transplant Recipients
The Spectrum of Ocular Manifestations among Renal Transplant Recipients Open
Purpose: The study aims to report various ocular manifestations among renal transplant recipients. Methods: The cross-sectional study was conducted on renal transplant patients, with at least 4 months of posttransplant duration, attending …
View article: Pre-Pulseless Takayasu Arteritis is Associated with Distinct Clinical and Angiographic Features but Similar Outcomes – A Cohort Study
Pre-Pulseless Takayasu Arteritis is Associated with Distinct Clinical and Angiographic Features but Similar Outcomes – A Cohort Study Open
Pulse loss on follow-up is uncommon in those with prepulseless TAK. Pre-pulseless TAK is associated with similar long-term outcomes to TAK with pulse loss.
View article: Increased mortality rate in Takayasu arteritis is largely driven by cardiovascular disease: a cohort study
Increased mortality rate in Takayasu arteritis is largely driven by cardiovascular disease: a cohort study Open
Objectives To analyse the risk, causes and predictors of mortality in Takayasu arteritis (TAK). Methods Survival was assessed in a cohort of patients with TAK using Kaplan–Meier curves. Age- and sex-standardized mortality ratio (SMR = obse…