Dharshini Gopal
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View article: Spatially patterned cytoskeletal organization shapes astrocyte branch complexity
Spatially patterned cytoskeletal organization shapes astrocyte branch complexity Open
Astrocytes, the most abundant cells in the brain, extend elaborate branches that enable diverse functions, from synapse maintenance to blood-brain-barrier integrity. The cytoskeletal basis of this architecture has remained unclear, since t…
View article: The Mn-motif protein MAP6d1 assembles ciliary doublet microtubules
The Mn-motif protein MAP6d1 assembles ciliary doublet microtubules Open
View article: Isolation, Detection and Analysis of Circulating Tumour Cells: A Nanotechnological Bioscope
Isolation, Detection and Analysis of Circulating Tumour Cells: A Nanotechnological Bioscope Open
Cancer is one of the dreaded diseases to which a sizeable proportion of the population succumbs every year. Despite the tremendous growth of the health sector, spanning diagnostics to treatment, early diagnosis is still in its infancy. In …
View article: Types of spectroscopy and microscopy techniques for cancer diagnosis: a review
Types of spectroscopy and microscopy techniques for cancer diagnosis: a review Open
View article: Deep learning-based image processing in optical microscopy
Deep learning-based image processing in optical microscopy Open
View article: Types of Optical Coherence Tomography for Cancer Diagnosis: A Systematic Review
Types of Optical Coherence Tomography for Cancer Diagnosis: A Systematic Review Open
Optical coherence tomography (OCT) is an emerging imaging technique that produces high contrast images that help distinguish different tissue layers by detecting the back-reflected near-infrared light. The technique is used to diagnose var…
View article: Carbon fullerene and nanotube are probable binders to multiple targets of SARS-CoV-2: Insights from computational modeling and molecular dynamic simulation studies
Carbon fullerene and nanotube are probable binders to multiple targets of SARS-CoV-2: Insights from computational modeling and molecular dynamic simulation studies Open
View article: Structural insights on the interaction potential of natural leads against major protein targets of SARS-CoV-2: Molecular modelling, docking and dynamic simulation studies
Structural insights on the interaction potential of natural leads against major protein targets of SARS-CoV-2: Molecular modelling, docking and dynamic simulation studies Open
View article: Elucidating Methods for Isolation and Quantification of Exosomes: A Review
Elucidating Methods for Isolation and Quantification of Exosomes: A Review Open
Exosomes are the smallest extracellular vesicles present in most of the biological fluids. They are found to play an important role in cell signaling, immune response, tumor metastasis, etc. Studies have shown that these vesicles also have…
View article: Structural and molecular basis of the interaction mechanism of selected drugs towards multiple targets of SARS-CoV-2 by molecular docking and dynamic simulation studies- deciphering the scope of repurposed drugs
Structural and molecular basis of the interaction mechanism of selected drugs towards multiple targets of SARS-CoV-2 by molecular docking and dynamic simulation studies- deciphering the scope of repurposed drugs Open
View article: Elucidating the microscopic and computational techniques to study the structure and pathology of <scp>SARS‐CoVs</scp>
Elucidating the microscopic and computational techniques to study the structure and pathology of <span>SARS‐CoVs</span> Open
Severe Acute Respiratory Syndrome Coronaviruses (SARS‐CoVs), causative of major outbreaks in the past two decades, has claimed many lives all over the world. The virus effectively spreads through saliva aerosols or nasal discharge from an …
View article: Carbon fullerene acts as potential lead molecule against prospective molecular targets of biofilm-producing multidrug-resistant <i>Acinetobacter baumanni</i> and <i>Pseudomonas aerugenosa</i>: computational modeling and MD simulation studies
Carbon fullerene acts as potential lead molecule against prospective molecular targets of biofilm-producing multidrug-resistant <i>Acinetobacter baumanni</i> and <i>Pseudomonas aerugenosa</i>: computational modeling and MD simulation studies Open
This study aimed to screen putative drug targets associated with biofilm formation of multidrug-resistant Acinetobacter baumannii and Pseudomonas areugenosa and prioritize carbon nano-fullerene as potential lead molecule by s…