Hendra Dian Adhita Dharsono
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Impact of Various Sleeve Materials on Temperature Variations During Guided Endodontic Access Cavity Preparation Utilizing Finite‐Element Analysis Open
Purpose Guided endodontics allows precise access in challenging cases such as calcified canals; however, drilling can generate temperature increases that risk damaging periradicular tissues. This study aimed to evaluate the influence of di…
Physicochemical and antibacterial evaluation of novel nano α-TCP–AgNPs biocomposites for direct pulp-capping applications Open
Background Nano α-tricalcium phosphate (nano α-TCP) and silver nanoparticles (AgNPs) both possess bioactive qualities needed for pulp-capping materials. AgNPs effectively combat microbial infections without sacrificing cell viability, whil…
Sleeve material, height, and drill surface changes in guided endodontics: vicker’s hardness and scanning electron microscope evaluation (A pilot study) Open
Background Guided endodontic access uses a CBCT-derived template with a guide sleeve to direct the drill for precise canal location, particularly in calcified teeth. This technique is more conservative, time-efficient, and accurate than co…
The differences of enamel hardness post application of silver diamine fluoride and fluoride varnish on demineralized tooth surface (in vitro) Open
This research aimed to determine the difference in enamel hardness after the application of silver diamine fluoride and fluoride varnish on the surface of demineralized tooth. An in vitro true experimental research was conducted by collect…
Potential of Secondary Metabolite Compounds of Black Cumin Seeds (Nigella sativa L.) as Therapeutic Agents for Chronic Diseases Open
Black cumin (Nigella sativa) has gained considerable attention in recent years due to its potential health benefits. This aromatic plant, native to the Middle East, North Africa, and South Asia, has long been used both as a culinary spice …
Sleeve Material, Height, and Drill Surface Changes in Guided Endodontics: Vicker’s Hardness and Scanning Electron Microscope Evaluation Open
Background Guided endodontic access uses a CBCT-derived template with a guide sleeve to direct the drill for precise canal location, particularly in calcified teeth. This technique is more conservative, time-efficient, and precise than con…
A Systematic Review of Research on Guided Access Cavity Preparation Endodontic Treatment: Dentin Preservation Perspectives Open
Article searches were conducted using the keywords "Guide Access Cavity Preparation" AND 'Static Guide OR 3D Printing Template' AND" Dynamic Guide through digital databases including PubMed, Scopus, Cochrane Library, Science Direct, and Go…
Phytochemical Analysis and Anti-Biofilm Potential That Cause Dental Caries from Black Cumin Seeds (Nigella sativa Linn.) Open
The oral cavity is an excellent place for various microorganisms to grow. Spectrococcus mutans and Spectrococcus sanguinis are Gram-negative bacteria found in the oral cavity as pioneer biofilm formers on the tooth surface that cause carie…
Stress Distribution of Endodontically Treated Tooth MOD Cavity Restored with Ribbon Fiber-Reinforced Composite (Wallpapering Technique) Using Finite Element Method Open
Neither the tooth nor restoration failed after vertical and horizontal loads. The interface between enamel and composite on the occlusal surface failed.
Stress Analysis on Mesiolingual Cavity of Endodontically Treated Molar Restored Using Bidirectional Fiber-Reinforced Composite (Wallpapering Technique) Open
The stress distribution of fiber-reinforced composite on the buccolingual cavity of ETT using the finite element method did not show structural failure in the polyethylene group because the maximum and minimum principal stresses were lower…
Exploring the Inhibitory Potential of <i>M. pendans</i> Compounds Against <i>N</i>‐Acetylglucosamine (Mur) Receptor: <i>In Silico</i> Insights Into Antibacterial Activity and Drug‐Likeness Open
Oral diseases are often caused by bacterial infections, making the inhibition of receptors like N ‐acetylglucosamine critical in preventing bacterial formation. The plant Myrmecodia pendans ( M. pendans ) is known for its diverse bioactivi…
In silico Study of Antiviral Activity of Polyphenol Compounds from Ocimum basilicum by Molecular Docking, ADMET, and Drug-Likeness Analysis Open
Based on the data obtained, Apigenin-7-glucuronide and dihydrokaempferol-3-glucoside are compounds that have more potential to have an antiviral effect on the main protease enzyme than aesculetin. Based on pharmacokinetic parameters and dr…
The Potential of 24-Propylcholestrol as Antibacterial Oral Bacteria of Enterococcus faecalis ATCC 29212 and Inhibitor Biofilms Formation: in vitro and in silico Study Open
24-propylcholesterol has potential as an antibacterial against E. faecalis and as an antibiofilm through in silico inhibition of QS. However, further research is needed in vitro and in vivo to determine the effectiveness of these compounds…
Ocimum Species: A Review on Chemical Constituents and Antibacterial Activity Open
Infection by bacteria is one of the main problems in health. The use of commercial antibiotics is still one of the treatments to overcome these problems. However, high levels of consumption lead to antibiotic resistance. Several types of a…
Mode action prediction of catechin from Uncaria gambir Roxb. against UDP-N-acetylenolpyruvyl-glucosamine reductase (MurB enzyme) of Streptococcus mutans Open
The prevalence of oral health problems in the global population is still high, especially dental caries, which is considered a multifactorial disease involving the role of bacteria, namely Streptococcus mutans . Gram-positive bacteria meta…
<strong>Antibacterial activity of strawberry fruit extract against <em>Streptococcus sanguinis</em> (ATCC 10556)</strong> Open
Introduction: Streptococcus sanguinis is a facultative anaerobic Gram-positive bacteria known as a pioneer that plays a role in creating the biofilm in the oral cavity. Strawberry fruit (Fragaria x ananassa) is an edible fruit widely used …
Antibacterial potential of strawberries and basil extracts combination against Streptococcus sanguinis (ATCC 10556) Open
Introduction: Streptococcus sanguinis is a commensal microorganism as well as a pioneer colony in forming dental plaque. Oral biofilm formation can be prevented by a mechanical cleaning procedure followed by the use of mouthwash. The curre…
Bio-Mechanism of Catechin as Pheromone Signal Inhibitor: Prediction of Antibacterial Agent Action Mode by In Vitro and In Silico Study Open
The utilization of medicinal plants has long been explored for the discovery of antibacterial agents and the most effective mechanisms or new targets that can prevent and control the spread of antibiotic resistance. One kind of bacterial c…
Action mode of ursolic acid as a natural antioxidant and inhibitor of superoxide dismutase Open
Recently, the antioxidant is applied for the teeth bleaching treatment as an alternative of toxic material of hydrogen peroxide that is used in teeth bleaching. One of natural sources antioxidant is Uncaria gambir those containing active a…
Effectiveness of Bioactive Compound as Antibacterial and Anti-Quorum Sensing Agent from Myrmecodia pendans: An In Silico Study Open
Background: antibiotic resistance encourages the development of new therapies, or the discovery of novel antibacterial agents. Previous research revealed that Myrmecodia pendans (Sarang Semut) contain potential antibacterial agents. Howeve…
Velocity and wall shear stress of 18% EDTA irrigation solution flow in the removal of Ca(OH)2 with computational fluid dynamic analysis Open
Introduction: Ethylene Diamine Tetra Acetic Acid (EDTA) 18% irrigation solution is one of the chelating agents that able to remove calcium hydroxide (Ca(OH)2) from the root canal wall. Failure of root canal treatment can be caused by the p…
Streamline characteristics using the computational fluid dynamic analysis in the flow of 18% EDTA irrigation solution to remove Ca(OH)2 Open
The remaining calcium hydroxide (Ca(OH)2) medicaments in the root canal wall can block the penetration of filling medicaments to the dentine tubule and cause the failure in the root canal treatment. One of the ways in cleaning the root can…
Antibacterial activity of Zingiber officinale roscoe extract as a potential root canal irrigation solution against Enterococcus faecalis Open
Introduction: This study was aimed to determine and formulate antibacterial activity of Zingiber Officinale Roscoe (Z. officinale) extract against Enterococcus faecalis (E. faecalis) as a potential irrigating solution which is easily avail…
Bioactive Compounds Isolated from Indonesian Epiphytic Plant of Sarang Semut and Their Antibacterial Activity against Pathogenic Oral Bacteria Open
A new phenolic compound (1), a steroid (2), a new steroid glycoside (4), two triterpenoids (3 & 6) and a new phloroglucinol-sesquiterpene (5) have been isolated from the ethyl acetate extract of Sarang Semut ( Myrmecodia pendans) and their…