Deepak Kumar
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View article: Pediatric Atypical Ulnar Tubercular Osteomyelitis with Diagnostic Dilemma
Pediatric Atypical Ulnar Tubercular Osteomyelitis with Diagnostic Dilemma Open
Skeletal tuberculosis (TB) remains a significant clinical entity, particularly in developing nations, where extrapulmonary TB contributes substantially to morbidity. TB involving the upper limb bones is rare, particularly in the pediatric …
View article: The predictive performance of NEWS, MEWS, SOFA and SAPS II in outcomes of bacteremic and non-bacteremic sepsis
The predictive performance of NEWS, MEWS, SOFA and SAPS II in outcomes of bacteremic and non-bacteremic sepsis Open
not applicable.
View article: Rete Ovarii Epithelial Cells as an Unappreciated Cell of Origin for Pelvic and Ovarian High-Grade Serous Carcinoma
Rete Ovarii Epithelial Cells as an Unappreciated Cell of Origin for Pelvic and Ovarian High-Grade Serous Carcinoma Open
Over the past two decades, converging clinicopathologic, molecular, and evolutionary evidence has established that pelvic and ovarian high-grade serous carcinoma (HGSC) originates predominantly from tubal-type epithelia rather than the ova…
View article: HBV HCV Co-Infection: A Dual Threat
HBV HCV Co-Infection: A Dual Threat Open
Background: The global HBV-HCV co-infection prevalence is estimated between 3%-30%. Such co-infected patients have a severe liver disease & and higher chances of hepatocellular carcinoma compared to mono infections. Moreover, many patients…
View article: Sonographic Assessment of Effectiveness of Ultrasound-guided Interventions for Soft-tissue Pain in Foot and Ankle
Sonographic Assessment of Effectiveness of Ultrasound-guided Interventions for Soft-tissue Pain in Foot and Ankle Open
Background: Ultrasound (US)-guided interventional procedures are used to relieve soft-tissue pain in the foot and ankle. We evaluated the utility of US (including Doppler and elastography) in the response assessment of patients undergoing …
View article: Study Protocol for a Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Desidustat Oral Tablet in Sickle Cell Disease: A Phase IIa Proof-of-Concept Evaluation
Study Protocol for a Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Desidustat Oral Tablet in Sickle Cell Disease: A Phase IIa Proof-of-Concept Evaluation Open
Background:Sickle cell disease (SCD) is a genetic disorder characterized by chronic hemolysis and vaso-occlusive crises. Desidustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), has shown promise in treating SCD…
View article: Association of Cosmic Ray Intensity decreases with Solar and Interplanetary Features during Solar Cycles 23 & 24
Association of Cosmic Ray Intensity decreases with Solar and Interplanetary Features during Solar Cycles 23 & 24 Open
The aim of this research work is to investigate the association of Forbush decreases with solar and interplanetary features i.e. sunspot number, solar radio flux, solar wind speed, solar plasma temperature, solar plasma density, interplane…
View article: Bacteriophage-mediated reduction of uropathogenic <i>E. coli</i> from the urogenital epithelium
Bacteriophage-mediated reduction of uropathogenic <i>E. coli</i> from the urogenital epithelium Open
Urinary tract infections (UTIs), primarily caused by uropathogenic Escherichia coli (UPEC), affect millions annually. UPEC gains access to the urinary tract through mucosal reservoirs including the vaginal tract. With rising antibiotic res…
View article: Impact of blood culture positivity on clinical outcomes in sepsis: a prospective observational study
Impact of blood culture positivity on clinical outcomes in sepsis: a prospective observational study Open
Although blood culture-positive sepsis was associated with higher disease severity at presentation, it did not result in increased 30-day mortality. These findings suggest that bacteremia alone does not determine sepsis outcomes, and cultu…
View article: PRAYAS: Cohort profile for Pooled Research and Analysis for Yielding Anemia-free Solutions in India
PRAYAS: Cohort profile for Pooled Research and Analysis for Yielding Anemia-free Solutions in India Open
Purpose This cohort would aim to estimate the prevalence of anemia among children under 18 years, non-pregnant and non-lactating (NPNL) women, and pregnant women (by trimester), with further stratification by age group, year, and region of…
View article: Efficacy & safety of stem cell therapy for treatment of acute myocardial infarction: A systematic review & meta-analysis
Efficacy & safety of stem cell therapy for treatment of acute myocardial infarction: A systematic review & meta-analysis Open
Background & Objectives Stem cell based therapeutic treatments have been used as a management strategy for acute myocardial infarction (AMI), a common primary factor causing death globally. We aimed to undertake a meta-analysis of studies …
View article: Assessment of WOMAC index for knee osteoarthritis and its association with serum vitamin - D and serum cytokine profile
Assessment of WOMAC index for knee osteoarthritis and its association with serum vitamin - D and serum cytokine profile Open
Vitamin D has immuno-modulatory and potential cartilage-regenerative effects. Therefore, it is of interest to evaluate the association between serum vitamin D levels, pro-inflammatory cytokines (IL-6, TNF-α), and functional status in patie…
View article: Role of Inflammatory Markers and Radiological Profile in Predicting Acute Pancreatitis Severity: A Prospective Analysis
Role of Inflammatory Markers and Radiological Profile in Predicting Acute Pancreatitis Severity: A Prospective Analysis Open
View article: An Observational Study on the Comparative Analysis of Trans Abdominal Preperitoneal and Totally Extraperitoneal: A Single-center Experience of 105 Patients
An Observational Study on the Comparative Analysis of Trans Abdominal Preperitoneal and Totally Extraperitoneal: A Single-center Experience of 105 Patients Open
Background: Inguinal hernia repair remains one of the most common surgical procedures performed in the elective setting. trans abdominal preperitoneal (TAPP) and totally extraperitoneal (TEP) are the two well-established laparoscopic metho…
View article: Impact of Rainy Environments on Nitrate Ion Detection in Post-blast Soil Analysis: A Forensic Study
Impact of Rainy Environments on Nitrate Ion Detection in Post-blast Soil Analysis: A Forensic Study Open
The forensic identification of nitrate ions in post-blast pit soil samples is crucial for investigating nitrate-based explosive incidents owing to environmental factors such as rainfall and monsoon conditions, which can significantly alter…
View article: Rapid detection and antimicrobial resistance profiling of pathogens causing neonatal sepsis using polymerase chain reaction: A prospective study
Rapid detection and antimicrobial resistance profiling of pathogens causing neonatal sepsis using polymerase chain reaction: A prospective study Open
Background: Neonatal sepsis remains a leading cause of morbidity and mortality, especially in preterm and very low birth weight infants. Increasing antimicrobial resistance and delays associated with conventional culture methods hinder tim…
View article: Comment on “Pediatric Infective Keratitis”
Comment on “Pediatric Infective Keratitis” Open
View article: SARS-CoV-2 infection disrupts syncytial and endothelial integrity and alters PLGF levels in the placenta
SARS-CoV-2 infection disrupts syncytial and endothelial integrity and alters PLGF levels in the placenta Open
Introduction: SARS-CoV-2 infection during pregnancy has been associated with an increased risk for several pregnancy-related disorders, particularly preeclampsia (PE). However, there are limited studies determining the impact of SARS-CoV-2…
View article: Perceived Social Support and Relapse in Bipolar Affective Disorder: A Cross-Sectional Study
Perceived Social Support and Relapse in Bipolar Affective Disorder: A Cross-Sectional Study Open
Bipolar affective disorder (BAD) is a chronic mental disorder with a global lifetime prevalence of 2.4%. Emerging evidence highlights the significance of psychosocial variables, particularly the impact of social support in its clinical cou…
View article: Bridging the gap: Early detection of pulmonary tuberculosis among PLHIV in Western Rajasthan, India
Bridging the gap: Early detection of pulmonary tuberculosis among PLHIV in Western Rajasthan, India Open
Background: Tuberculosis (TB) remains a leading cause of mortality among people living with HIV (PLHIV), with delayed diagnosis contributing significantly to poor outcomes. Early detection through systematic screening and diagnostic tools …
View article: Use of Cucurma longa and Coriandrum sativum powder as dietary supplements enhances growth performance, expression of growth-related nutritional genes and maintenance in broiler chickens
Use of Cucurma longa and Coriandrum sativum powder as dietary supplements enhances growth performance, expression of growth-related nutritional genes and maintenance in broiler chickens Open
A 35-day trial was conducted using day-old Cobb 400Y broiler chicks (N=200) to investigate the effects of incorporating turmeric (Curcuma longa) and coriander (Coriandrum sativum) powders, both individually and in combination, on growth pe…
View article: Tracing Early Molecular Drivers of Gastrinoma in MEN1: A Systematic Review for Precision Surveillance and Improved Patient Outcomes
Tracing Early Molecular Drivers of Gastrinoma in MEN1: A Systematic Review for Precision Surveillance and Improved Patient Outcomes Open
Objective This study aims to investigate the increased risk in Multiple Endocrine Neoplasia type 1 patients to develop gastrinomas later in life. It focuses on the mechanisms that may come into play in duodenal enteroendocrine cells to res…
View article: <b>ROLE OF ANGIOEMBOLIZATION IN ABDOMINOPELVIC TRAUMA PATIENTS: RESULTS OF ANGIOEMBOLIZATION AND EFFECT OF TIME DURATION BETWEEN TRAUMA AND EMBOLIZATION PROCEDURE</b>
<b>ROLE OF ANGIOEMBOLIZATION IN ABDOMINOPELVIC TRAUMA PATIENTS: RESULTS OF ANGIOEMBOLIZATION AND EFFECT OF TIME DURATION BETWEEN TRAUMA AND EMBOLIZATION PROCEDURE</b> Open
Objective: The proposed study aims to look at the outcomes of angioembolization in terms of survival, blood transfusions, length of ICU stay, and overall stay, need for surgical exploration. Methods: After the ethical approval from institu…
View article: Evaluation of Salivary Biomarkers in the Early Detection of Oral Squamous Cell Carcinoma
Evaluation of Salivary Biomarkers in the Early Detection of Oral Squamous Cell Carcinoma Open
A BSTRACT Background: The most prevalent malignant tumor affecting the oral cavity is called oral squamous cell carcinoma (OSCC). Improving patient outcomes and survival rates requires early identification. Salivary biomarkers have drawn a…
View article: Study of Clostridioides Difficile Associated Diarrhea in Acute Care Areas of a Tertiary Care Centre in Western Rajasthan- A Prospective Study
Study of Clostridioides Difficile Associated Diarrhea in Acute Care Areas of a Tertiary Care Centre in Western Rajasthan- A Prospective Study Open
Purpose: The aim of this study is to identify Clostridioides difficile associated diarrhoea (CDAD) in patients admitted to acute care units of the hospital. It also examines different detection methods, including anaerobic culture, GDH ass…
View article: Optimizing Forensic Detection of Explosive Substances: Extended Column Analysis of TNT
Optimizing Forensic Detection of Explosive Substances: Extended Column Analysis of TNT Open
Trinitrotoluene (TNT) is a secondary high explosive substance which is found in many explosive compositions. It is used for military and industrial purposes; however, it is also misused for illegal and terrorist activities. Forensic analys…
View article: “Dual Subsartorial Block”: A Novel Technique for Postoperative Pain Management in a Pediatric Patient Undergoing Arthroscopic Meniscectomy
“Dual Subsartorial Block”: A Novel Technique for Postoperative Pain Management in a Pediatric Patient Undergoing Arthroscopic Meniscectomy Open
Meniscal injury is commonly seen in adults when compared to children. In children, adolescents are more prone to meniscal injuries with the most common cause being high-intensity sports activities. Discoid meniscus, which is a congenital v…
View article: Comparative Assessment of Health Risks Associated with E-Cigarettes versus Conventional Cigarettes: An Original Study in the Navi Mumbai Population
Comparative Assessment of Health Risks Associated with E-Cigarettes versus Conventional Cigarettes: An Original Study in the Navi Mumbai Population Open
View article: Trace Analysis of Nitrate Content in Soil Samples using Ion Chromatography from Forensic Perspective
Trace Analysis of Nitrate Content in Soil Samples using Ion Chromatography from Forensic Perspective Open
Soil samples are often sent to Forensic Science Laboratories (FSLs) as exhibits to determine the presence of explosive residues in post-blast cases. This work focuses on the trace analysis of nitrate ion (NO3¯) content in the soil samples …
View article: EARLY DIAGNOSIS OF AUTISM SPECTRUM DISORDER USING M-CHAT R/F SCREENING TOOL AMONG TODDLERS IN PEDIATRIC OUTDOOR CLINIC - A CROSS SECTIONAL STUDY
EARLY DIAGNOSIS OF AUTISM SPECTRUM DISORDER USING M-CHAT R/F SCREENING TOOL AMONG TODDLERS IN PEDIATRIC OUTDOOR CLINIC - A CROSS SECTIONAL STUDY Open