Explanipedia

Hybridized Active Fiber and Fiber Amplifier for Broadband Coherent Optical Communication Open

Yi Han, Tianxia Wei, Chao Li, Ziang Liu, Yupeng Huang , et al. · 2025

The rapid developments of technologies create an urgent requirement for increasing the capacity of the optical fiber communication system. The most promising way is to extend the communication wavebands. Here, it is reported that the hybri…

Hybrid Photonic Glass for Optical Sensing Open

Hongwei Li, Xueliang Li, Dazhao Wang, Jianfeng Yan, Shichao Lv , et al. · 2025

Metal‐organic frameworks (MOFs) glass is a newly invented hybrid materials with the unique optical response and great potential for photonic applications. Unfortunately, limited by the high viscosity and instability issue of the ZIF‐62 pre…

Renewable composite fiber for spatial radiation detection Open

Yankun Qi, Hongwei Li, Feng Zhang, Dianhao Hou, Dazhao Wang , et al. · 2025

Radiation detection is a common theme in various significant fields including radiotherapy, nuclear industry, aerospace, and environmental monitoring. Radiophotoluminescence (RPL) materials are widely used for radiation detection, but almo…

Partial response to lorlatinib in thoracic inflammatory myofibroblastic tumor harboring complex and rare ALK fusions: a case report Open

Li-Bo Tang, Yinglong Peng, Xiaorong Yang, Jia-Ting Li, Chang Lu , et al. · 2025

This is the inaugural case of a third-generation ALK-TKI achieving therapeutic success in advanced IMT with complex ALK rearrangements, including rare and previously uncharacterized fusion subtypes. Although the biological functions of the…

Asynchronous Federated Learning Based Zero Trust Architecture for the Next Generation Industrial Control Systems Open

Fei Lv, Hangyu Wang, Zhiwen Pan, Rongkang Sun, Shuaizong Si , et al. · 2025

Scale-based screening and assessment of age-related frailty Open

Xiaoming Wang, Yuanhui Zhang, Chenchen Meng, Lu Fan, Lei Wei , et al. · 2024

As the population ages, the prevalence of age-related frailty increases sharply, which increases the risk of poor health status of older adults, such as disability, falls, hospitalization, and death. Across the globe, frailty is moving tow…

The Potential Therapeutic Prospect of PANoptosis in Heart Failure Open

Yunfeng Jia, Yayi Liu, Yiming Zuo, Junping Zhang, Yanyang Li , et al. · 2024

Heart failure (HF) represents a serious manifestation or advanced stage of various cardiac diseases. HF continues to impose a significant global disease burden, characterized by high rates of hospitalization and fatality. Furthermore, the …

Estrogen enhances the proliferation, migration, and invasion of papillary thyroid carcinoma via the ERα/KRT19 signaling axis Open

Zhilong Song, Y. D. Wang, Fang Chai, Jing Zhang, Shichao Lv , et al. · 2024

Background Estrogen is thought to be the reason for the higher prevalence of papillary thyroid carcinoma (PTC) in fertile women; however, more study is required to completely comprehend how estrogen affects PTC development at the cellular …

WITHDRAWN: Shenmai Injection Exerts the Cardioprotective Effects by Modulating Autophagy-apoptosis via Beclin-1 Open

Yanyang Li, Lu Fan, Xiaoming Wang, Yiming Zuo, Yayi Liu , et al. · 2024

Transparent composites for efficient neutron detection Open

Shichao Lv, Dazhao Wang, Junzhou Tang, Ziang Liu, H. Inoue , et al. · 2024

Detection of Cyberattack in Industrial Control Networks Using Multiple Adaptive Local Kernel Learning Open

Fei Lv, Hangyu Wang, Rongkang Sun, Zhiwen Pan, Shuaizong Si , et al. · 2024

A new perspective in the prevention and treatment of antitumor therapy-related cardiotoxicity: Intestinal microecology Open

Chenchen Meng, Xiaoming Wang, Lu Fan, Yajie Fan, Zhipeng Yan , et al. · 2023

The continuous development of antitumor therapy has significantly reduced the mortality of patients with malignancies. However, the antitumor-related cardiotoxicity has become the leading cause of long-term mortality in patients with malig…

Shenmai injection ameliorates doxorubicin-induced myocardial injury by suppressing autophagy-apoptosis via miR-30a Open

Yanyang Li, Lu Fan, Xiaoming Wang, Shichao Lv · 2023

Shenmai injection inhibited autophagy and apoptosis via miR-30a, thereby alleviating doxorubicin-induced myocardial injury.

Super-elastic Scintillating Fibers and Fabrics for Efficient and Visual Radiation Detection Open

Minghui Du, Jin Wang, Sijia Xu, Hongwei Li, Zhihao Zhang , et al. · 2023

The fabrication of advanced radiation detectors is an important subject due to the wide use of radiation sources in scientific instruments, medical services, security check, non-destructive inspection, and nuclear industries. However, the …

Comparison of a One- versus Two-Week Treatment with Famciclovir Upon Reductions in Pain and Occurrence of Postherpetic Neuralgia in Herpes Zoster: A Randomized Open-Label Trial Open

Fen Peng, Haiyang He, Tianbao Xia, Shichao Lv · 2023

It suggests that longer administration of famciclovir has no further benefit in the treatment of herpes zoster in our study.

Driving force of deteriorated cellular environment in heart failure: Metabolic remodeling Open

Lu Fan, Chenchen Meng, Xiaoming Wang, Yunjiao Wang, Yanyang Li , et al. · 2023

Heart Failure (HF) has been one of the leading causes of death worldwide. Though its latent mechanism and therapeutic manipulation are updated and developed ceaselessly, there remain great gaps in the cognition of heart failure. High morbi…

The chemical components, action mechanisms, and clinical evidences of YiQiFuMai injection in the treatment of heart failure Open

Shichao Lv, Yunjiao Wang, Wanqin Zhang, Hongcai Shang · 2022

YiQiFuMai injection (YQFM), derived from Shengmai Powder, is wildly applied in the treatment of cardiovascular diseases, such as coronary heart disease and chronic cardiac insufficiency. YiQiFuMai injection is mainly composed of Radix of P…

QishenYiqi dripping pill protects against myocardial ischemia/reperfusion injury via suppressing excessive autophagy and NLRP3 inflammasome based on network pharmacology and experimental pharmacology Open

Meng Li, Yueyao Wang, Zhongwen Qi, Zhuo Yuan, Shichao Lv , et al. · 2022

Background: Myocardial ischemia/reperfusion (I/R) injury is associated with multiple serious clinical manifestations. Autophagy is upregulated in a short period of ischemia and further enhanced during reperfusion phase, which was considere…

QiShenYiQi pill for myocardial collagen metabolism and apoptosis in rats of autoimmune cardiomyopathy Open

Shichao Lv, Wanqin Zhang, Peng Yuan, Chunmiao Lu, Jianping Dong , et al. · 2022

The QSYQ can improve myocardial collagen metabolism by inhibiting apoptosis, which provides a potential therapeutic approach for autoimmune cardiomyopathy.

Preparation and Evaluation of Animal Models of Cardiotoxicity in Antineoplastic Therapy Open

Chenchen Meng, Lu Fan, Xiaoming Wang, Yunjiao Wang, Yanyang Li , et al. · 2022

The continuous development of antineoplastic therapy has significantly reduced the mortality of patients with malignant tumors, but its induced cardiotoxicity has become the primary cause of long‐term death in patients with malignant tumor…

Structured Scintillators for Efficient Radiation Detection Open

Ziyu Lin, Shichao Lv, Zhongmin Yang, Jianrong Qiu, Shifeng Zhou · 2021

Scintillators, which can convert high‐energy ionizing radiation into visible light, have been serving as the core component in radiation detectors for more than a century of history. To address the increasing application demands along with…

Shenmai Injection Alleviates Cardiomyocyte Apoptosis Induced by Doxorubicin Open

Xiaonan Zhang, Yanyang Li, Wanqin Zhang, Qiujin Jia, Yaping Zhu , et al. · 2021

Background: Shenmai Injection (SMI) is a patented Chinese medicine extract, has been widely used to treat myocardial damage caused by doxorubicin (DOX), but its underlying mechanisms remain elusive. The study aimed to explore the protectiv…

QiShenYiQi Pill Improves Myocardial Hypertrophy Caused by Pressure Overload in Rats Open

Shichao Lv, Qiang Wang, Meifang Wu, Meng Li, Xiaojing Wang , et al. · 2021

Pressure-overloaded myocardial hypertrophy is an independent risk factor for various cardiovascular diseases (CVDs), such as heart failure (HF), arrhythmia, and even sudden death. It is reported that QiShenYiQi pill (QSYQ) is widely used i…

Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1 Open

Xiaonan Zhang, Shichao Lv, Wanqin Zhang, Qiujin Jia, Lirong Wang , et al. · 2021

The emerging role of circular RNAs in cardiovascular diseases Open

Yuejia Ding, Chunmiao Lu, Wanqin Zhang, Yuan Wang, Yanyang Li , et al. · 2021

Cardiovascular disease (CVD) is one of the vital causes of morbidity and mortality, and the number of deaths from CVD has increased worldwide. Circular RNAs (circRNAs) is a novel type of endogenous noncoding RNA, which can form covalent cl…

QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway Open

Shichao Lv, Peng Yuan, Chunmiao Lu, Jianping Dong, Meng Li , et al. · 2021

QiShenYiQi pill (QSYQ), a traditional Chinese medicine, is used to treat cardiovascular diseases. However, the dose-effect relationship of its intervention in the reactive myocardial fibrosis is elusive. In this work, rat models of reactiv…

QiShenYiQi pill improves the reparative myocardial fibrosis by regulating autophagy Open

Shichao Lv, Peng Yuan, Jianping Dong, Chunmiao Lu, Meng Li , et al. · 2020

QiShenYiQi pill (QSYQ), a traditional Chinese medicine, is well known for improving the myocardial remodelling, but the dose‐effect relationship of its intervention in the reparative myocardial fibrosis is still unclear. We investigated th…

QiShenYiQi Pill Improves Myocardial Hypertrophy Caused by Pressure Overload in Rats Open

Shichao Lv, Qiang Wang, Meifang Wu, Meng Li, Xiaojing Wang , et al. · 2020

Background: QiShenYiQi pill (QSYQ), a traditional Chinese medicine, is widely used in the treatment of cardiovascular diseases, but its specific mechanism of action is still unclear. In the current study, we investigated the effect of QSYQ…

Morphological and Functional Characteristics of Animal Models of Myocardial Fibrosis Induced by Pressure Overload Open

Yuejia Ding, Yuan Wang, Qiujin Jia, Xiaoling Wang, Yanmin Lu , et al. · 2020

Myocardial fibrosis is characterized by excessive deposition of myocardial interstitial collagen, abnormal distribution, and excessive proliferation of fibroblasts. According to the researches in recent years, myocardial fibrosis, as the p…

Roles of Biomarkers in Myocardial Fibrosis Open

Yuejia Ding, Yuan Wang, Wanqin Zhang, Qiujin Jia, Xiaoling Wang , et al. · 2020

Myocardial fibrosis is observed in various cardiovascular diseases and plays a key role in the impairment of cardiac function. Endomyocardial biopsy, as the gold standard for the diagnosis of myocardial fibrosis, has limitations in terms o…

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