Diamond Gallimore
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View article: Comparative Analysis of Drug-like EP300/CREBBP Acetyltransferase Inhibitors
Comparative Analysis of Drug-like EP300/CREBBP Acetyltransferase Inhibitors Open
The human acetyltransferase paralogues EP300 and CREBBP are master regulators of lysine acetylation whose activity has been implicated in various cancers. In the half-decade since the first drug-like inhibitors of these proteins were repor…
View article: Comparative analysis of drug-like EP300/CREBBP acetyltransferase inhibitors
Comparative analysis of drug-like EP300/CREBBP acetyltransferase inhibitors Open
The human acetyltransferase paralogs EP300 and CREBBP are master regulators of lysine acetylation whose activity has been implicated in various cancers. In the half-decade since the first drug-like inhibitors of these proteins were reporte…
View article: Protonation-Dependent Sequencing of 5-Formylcytidine in RNA
Protonation-Dependent Sequencing of 5-Formylcytidine in RNA Open
Chemical modification of cytidine in noncoding RNAs plays a key role in regulating translation and disease. However, the distribution and dynamics of many of these modifications remain unknown due to a lack of sensitive site-specific seque…