Didier Hannouche
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View article: Intracellular autofluorescence enables the isolation of viable, functional human muscle reserve cells with distinct Pax7 levels and stem cell states
Intracellular autofluorescence enables the isolation of viable, functional human muscle reserve cells with distinct Pax7 levels and stem cell states Open
Background Human muscle reserve cells (MuRC) represent a quiescent MuSC population generated in vitro that exhibit heterogeneous Pax7 expression, with a Pax7 High subset in a deeper quiescent state. However, the conventional method of iden…
View article: Factors Associated With the Risk of Neuropathic Pain One Year After Total Knee Arthroplasty and the Protective Role of Local Infiltration Analgesia: A Registry‐Based Prospective Cohort Study
Factors Associated With the Risk of Neuropathic Pain One Year After Total Knee Arthroplasty and the Protective Role of Local Infiltration Analgesia: A Registry‐Based Prospective Cohort Study Open
Objective To identify predictors of reduced risk for neuropathic pain (NP) one year after total knee arthroplasty (TKA) among patients who did not report NP before surgery. Methods We included primary TKAs performed between January 1, 2014…
View article: Activity outcomes after hip arthroplasty: an information tool based on patients’ experience captured in a hospital registry
Activity outcomes after hip arthroplasty: an information tool based on patients’ experience captured in a hospital registry Open
Background and purpose Patients receiving total hip arthroplasty (THA) have different expectations and concerns about their health outcomes after surgery. In this study we developed a tool based on registry data to inform patients and thei…
View article: Association of preoperative health status with risk of complications after primary total hip arthroplasty: how useful are the measures self-rated health, ASA classification and comorbidity count?
Association of preoperative health status with risk of complications after primary total hip arthroplasty: how useful are the measures self-rated health, ASA classification and comorbidity count? Open
SRH, ASA classification and comorbidity count showed increasing risks of medical complications and death with decreasing health status. ASA was most strongly associated with death. Regarding revision both comorbidity count and ASA performe…
View article: Coronal Plane Alignment of the Knee Classification in Osteoarthritic Knees: Poor to Moderate Reliability and Implications for Imaging Choice
Coronal Plane Alignment of the Knee Classification in Osteoarthritic Knees: Poor to Moderate Reliability and Implications for Imaging Choice Open
IV, retrospective cohort.
View article: Comparison of Results of Total Hip Arthroplasty in Patients Under 50 Years Who Had Osteonecrosis of the Femoral Head or Osteoarthritis: A Propensity-Matched Cohort Study From the Geneva Arthroplasty Registry With a Mean 12-Year Follow-Up
Comparison of Results of Total Hip Arthroplasty in Patients Under 50 Years Who Had Osteonecrosis of the Femoral Head or Osteoarthritis: A Propensity-Matched Cohort Study From the Geneva Arthroplasty Registry With a Mean 12-Year Follow-Up Open
Level III, Case-Control Studies.
View article: Validity of a Single Inertial Measurement Unit to Measure Hip Range of Motion During Gait in Patients Undergoing Total Hip Arthroplasty
Validity of a Single Inertial Measurement Unit to Measure Hip Range of Motion During Gait in Patients Undergoing Total Hip Arthroplasty Open
Hip flexion range of motion (ROM) during gait is an important surgery outcome for patients undergoing total hip arthroplasty (THA) that could help patient monitoring and rehabilitation. To allow systematic measurements during patients’ cli…
View article: Allogenic Bioengineered Cartilage Achieves Hyaline Cartilage Repair in a Large Animal Model: A Promising Step Forward
Allogenic Bioengineered Cartilage Achieves Hyaline Cartilage Repair in a Large Animal Model: A Promising Step Forward Open
Background: Chondrocyte-based cell therapy remains a promising method for cartilage repair, despite limitations faced during the last 30 years. Purpose/Hypothesis: This work presents hyaline-like bioengineered beads from donor chondrocytes…
View article: La déformation de type came dans le conflit fémoro-acétabulaire – un facteur de risque arthrosique. Et si on la résèque ?
La déformation de type came dans le conflit fémoro-acétabulaire – un facteur de risque arthrosique. Et si on la résèque ? Open
View article: Isolated acetabular cup revision in Metal-on-Metal total hip arthroplasty: a low-complication strategy feasible in only half of cases
Isolated acetabular cup revision in Metal-on-Metal total hip arthroplasty: a low-complication strategy feasible in only half of cases Open
Purpose There is still a debate regarding the removal of the femoral stem due to the risk of trunnion. To answer this question, we conducted a study to compare long terms outcomes of isolated acetabular to total revision of MoM THA using a…
View article: Intracellular autofluorescence enables the isolation of viable, functional human muscle reserve cells with distinct Pax7 levels and stem cell states
Intracellular autofluorescence enables the isolation of viable, functional human muscle reserve cells with distinct Pax7 levels and stem cell states Open
Background Human muscle reserve cells (MuRC) represent a quiescent MuSC population generated in vitro that exhibit heterogeneous Pax7 expression, with a Pax7 High subset in a deeper quiescent state. However, conventional identification of …
View article: Long-term outcomes of small head metal-on-metal compared to ceramic-on-polyethylene primary total hip arthroplasty: a registry-based cohort study
Long-term outcomes of small head metal-on-metal compared to ceramic-on-polyethylene primary total hip arthroplasty: a registry-based cohort study Open
Purpose We aimed to compare the long-term outcomes of small-head (28 mm) metal-on-metal (MoM) total hip arthroplasty (THA) to ceramic-on-polyethylene (CoP) THA using the same cup. Methods All primary elective MoM and CoP THAs performed 199…
View article: ReFORM : un réseau innovant au service de la médecine du sport et des sportifs au sein de la francophonie
ReFORM : un réseau innovant au service de la médecine du sport et des sportifs au sein de la francophonie Open
View article: Wear factor comparison between single and dual mobility cup in total hip arthroplasty
Wear factor comparison between single and dual mobility cup in total hip arthroplasty Open
View article: Intensive physical activity following total hip arthroplasty increased the revision risk after 15 years: a cohort study of 973 patients from the Geneva Arthroplasty Register
Intensive physical activity following total hip arthroplasty increased the revision risk after 15 years: a cohort study of 973 patients from the Geneva Arthroplasty Register Open
Background and purpose: Younger recipients of total hip arthroplasty (THA) highly prioritize returning to preoperative levels of physical activity (PA). Surgeons have tended to give cautious advice concerning high-impact sports participati…
View article: Microfractures, autologous matrix-induced chondrogenesis, osteochondral autograft transplantation and autologous chondrocyte implantation for knee chondral defects: a systematic review and network meta-analysis of randomized controlled trials
Microfractures, autologous matrix-induced chondrogenesis, osteochondral autograft transplantation and autologous chondrocyte implantation for knee chondral defects: a systematic review and network meta-analysis of randomized controlled trials Open
Purpose Despite the publication of several randomized controlled trials (RCTs), it is not clear which technique for the treatment of focal chondral and osteochondral defects of the knee grants the best clinical outcome. The aim of this net…
View article: Activity outcomes after hip arthroplasty: an information tool based on patients’ experience captured in a hospital registry
Activity outcomes after hip arthroplasty: an information tool based on patients’ experience captured in a hospital registry Open
Background and purpose Patients receiving total hip arthroplasty (THA) have different expectations and concerns about their health outcomes after surgery. In this study we developed a tool based on registry data to inform patients and thei…
View article: Platelet-Rich Plasma Promotes the Expansion of Human Myoblasts and Favors the In Vitro Generation of Human Muscle Reserve Cells in a Deeper State of Quiescence
Platelet-Rich Plasma Promotes the Expansion of Human Myoblasts and Favors the In Vitro Generation of Human Muscle Reserve Cells in a Deeper State of Quiescence Open
View article: Patients’ experience on pain outcomes after hip arthroplasty: insights from an information tool based on registry data
Patients’ experience on pain outcomes after hip arthroplasty: insights from an information tool based on registry data Open
Background Arthroplasty registries are rarely used to inform encounters between clinician and patient. This study is part of a larger one which aimed to develop an information tool allowing both to benefit from previous patients’ experienc…
View article: 801 EP014 – Enhancing concussion prevention: findings from an international survey of French-speaking athletes on sport-related concussion characteristics
801 EP014 – Enhancing concussion prevention: findings from an international survey of French-speaking athletes on sport-related concussion characteristics Open
peer reviewed
View article: Radiographic signs and hip pain 5 years after THA with a cemented stem predict future revision for aseptic loosening: a prospective cohort study
Radiographic signs and hip pain 5 years after THA with a cemented stem predict future revision for aseptic loosening: a prospective cohort study Open
Background and purpose: We aimed to evaluate the long-term predictive value of radiographic abnormality and/or hip pain assessed 5 years following primary total hip arthroplasty (THA) and the occurrence of revision for aseptic loosening be…
View article: Reliability of the Harris Hip limping sub-score in patients undergoing total hip arthroplasty
Reliability of the Harris Hip limping sub-score in patients undergoing total hip arthroplasty Open
Purpose In patients undergoing total hip arthroplasty, limping is a significant symptom, often assessed with the limping sub-score of the Harris Hip Score. However, the reliability of this sub-score has not been specifically investigated. …
View article: Sensor-to-Bone Calibration with the Fusion of IMU and Bi-Plane X-rays
Sensor-to-Bone Calibration with the Fusion of IMU and Bi-Plane X-rays Open
Inertial measurement units (IMUs) need sensor-to-segment calibration to measure human kinematics. Multiple methods exist, but, when assessing populations with locomotor function pathologies, multiple limitations arise, including holding po…
View article: In vitro-generated human muscle reserve cells are heterogeneous for Pax7 with distinct molecular states and metabolic profiles
In vitro-generated human muscle reserve cells are heterogeneous for Pax7 with distinct molecular states and metabolic profiles Open
View article: Patients’ experience to inform decision-making and clinical follow-up: The example of total hip arthroplasty
Patients’ experience to inform decision-making and clinical follow-up: The example of total hip arthroplasty Open
Background The aim of this project was to enable patients and clinicians to benefit from previous patients’ experiences with total hip arthroplasty (THA) by seeking out patients’ views on what is important for them, leveraging registry dat…
View article: Association of preoperative health status with risk of complications after primary total hip arthroplasty: How useful are the measures self-rated health, ASA classification and comorbidity count?
Association of preoperative health status with risk of complications after primary total hip arthroplasty: How useful are the measures self-rated health, ASA classification and comorbidity count? Open
Background Complications after surgery can be predicted using ASA classification or comorbidity count. No study has assessed the measure self-rated health (SRH) yet. Our objective was to assess the association between SRH, ASA and comorbid…
View article: Estimation of two wear factors for total hip arthroplasty: A simulation study based on musculoskeletal modelling
Estimation of two wear factors for total hip arthroplasty: A simulation study based on musculoskeletal modelling Open
View article: Extensive skin necrosis following total hip arthroplasty performed through the direct anterior approach
Extensive skin necrosis following total hip arthroplasty performed through the direct anterior approach Open
View article: The modern state of femoral, acetabular, and global offsets in total hip arthroplasty: a narrative review
The modern state of femoral, acetabular, and global offsets in total hip arthroplasty: a narrative review Open
Offsets in the frontal plane are important for hip function. Research on total hip arthroplasty (THA) surgery agrees that increasing femoral offset up to 5 mm could improve functional outcome measures. The literature indicates that global …
View article: NADPH oxidase 4 deficiency attenuates experimental osteoarthritis in mice
NADPH oxidase 4 deficiency attenuates experimental osteoarthritis in mice Open
Objective Low-grade inflammation plays a pivotal role in osteoarthritis (OA) through exposure to reactive oxygen species (ROS). In chondrocytes, NADPH oxidase 4 (NOX4) is one of the major ROS producers. In this study, we evaluated the role…