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View article: Assessing cognitive impairment in OSAHS patients through NODDI-based gray matter analysis
Assessing cognitive impairment in OSAHS patients through NODDI-based gray matter analysis Open
This study suggests the potential diagnostic utility of NODDI in detecting gray matter pathology in OSAHS patients with cognitive impairment, though further validation in larger, independent cohorts is needed.
View article: Advances in the diagnosis and treatment of primary malignant melanoma of the vagina- a case presentation and systematic review
Advances in the diagnosis and treatment of primary malignant melanoma of the vagina- a case presentation and systematic review Open
PVM is highly malignant with a poor prognosis, and surgical resection remains the primary treatment modality; however, its efficacy is limited. While chemotherapy may benefit some patients, the five-year survival rate ranging from 5 to 25%…
View article: A case report of retroperitoneal leiomyosarcoma originating from the right ovarian vein and invading the right renal vein and inferior vena cava
A case report of retroperitoneal leiomyosarcoma originating from the right ovarian vein and invading the right renal vein and inferior vena cava Open
A woman in her early 50s was admitted to our hospital with a right retroperitoneal tumor that had been detected >1 year ago. Imaging studies revealed a mass in the right middle and lower retroperitoneum, which involved the upper portion of…
View article: Prediction of Insulin Resistance in Nondiabetic Population Using LightGBM and Cohort Validation of Its Clinical Value: Cross-Sectional and Retrospective Cohort Study
Prediction of Insulin Resistance in Nondiabetic Population Using LightGBM and Cohort Validation of Its Clinical Value: Cross-Sectional and Retrospective Cohort Study Open
Background Insulin resistance (IR), a precursor to type 2 diabetes and a major risk factor for various chronic diseases, is becoming increasingly prevalent in China due to population aging and unhealthy lifestyles. Current methods like the…
View article: Therapeutic Targets for Multiple System Atrophy
Therapeutic Targets for Multiple System Atrophy Open
Background and Objectives: Multiple System Atrophy (MSA) is a progressive neurodegenerative disorder with no effective treatment. This research aims to identify novel potential therapeutic targets for MSA using systematic druggable genome-…
View article: [Anti-HMGCR immune-mediated necrotizing myopathy: A case report].
[Anti-HMGCR immune-mediated necrotizing myopathy: A case report]. Open
The patient was a 55-year-old man who was admitted to hospital with "progressive myalgia and weakness for 4 months, and exacerbated for 1 month". Four months ago, he presented with persistent shoulder girdle myalgia and elevated creatine k…
View article: [Diagnostic value of F wave changes in patients with Charcot-Marie-Tooth1A and chronic inflammatory demyelinating polyneuropathy].
[Diagnostic value of F wave changes in patients with Charcot-Marie-Tooth1A and chronic inflammatory demyelinating polyneuropathy]. Open
The prolonged latency of F wave in patients with CMT1A reflects the homogenous changes in both proximal and distal peripheral nerves, which can be used as a method to differentiate the CIDP patients characterized by focal demyelinating pat…
View article: [Cortical thickness and cognitive impairment in patients with amyotrophic lateral sclerosis].
[Cortical thickness and cognitive impairment in patients with amyotrophic lateral sclerosis]. Open
The cortical thickness of ALS patients are correlated with neuropsychological scores which may reflect the changes of cortical structure corresponding to the cognitive assessment, and may provide help for the early diagnosis of cognitive c…
View article: [Genetic distribution in Chinese patients with hereditary peripheral neuropathy].
[Genetic distribution in Chinese patients with hereditary peripheral neuropathy]. Open
CMT and HMN are the most common diseases of HPN. There is a large overlap between HMN and motor-CMT2 pathogenic genes, and some HMN pathogenic genes overlap with amyotrophic lateral sclerosis, hereditary spastic hemiplegia and spinal muscu…
View article: [Diagnostic value of tremor analysis in identifying the early Parkinson's syndrome].
[Diagnostic value of tremor analysis in identifying the early Parkinson's syndrome]. Open
Tremor analysis is sensitive and a superior way in identifying early Parkinson's syndrome patients with tremor dominant manifestation. The combination of non-motor symptoms and transcranial sonography are also needed at diagnosis.
View article: Amyotrophic lateral sclerosis and motor neuron syndromes in Asia
Amyotrophic lateral sclerosis and motor neuron syndromes in Asia Open
While the past 2 decades have witnessed an increasing understanding of amyotrophic lateral sclerosis (ALS) arising from East Asia, particularly Japan, South Korea, Taiwan and China, knowledge of ALS throughout the whole of Asia remains lim…