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View article: Severe invasive Streptococcus pyogenes infections: A 15-year observational study with molecular characterization of isolates among intensive care adults
Severe invasive Streptococcus pyogenes infections: A 15-year observational study with molecular characterization of isolates among intensive care adults Open
The incidence of iGAS infections requiring ICU admission showed no significant increase post-Coronavirus Disease-19 pandemic. The highly toxigenic M1uk strain became predominant, but it was not associated with worse mortality among adult I…
View article: Cárie Radicular: Uma doença bucal prevalente em idosos
Cárie Radicular: Uma doença bucal prevalente em idosos Open
Atualmente, observou-se um aumento na quantidade de pessoas com mais de 60 anos, os idosos, em diversas regiões do planeta. No entanto, a saúde bucal dessa faixa etária apresenta muitas fragilidades, e uma delas é a cárie radicular. A cári…
View article: Mycoplasma penetrans urethritis in men. A case–control study
Mycoplasma penetrans urethritis in men. A case–control study Open
Introduction A microbiological diagnosis is not reached in many urethritis cases, the proportion varying with the diagnostic methods and targets available. Mycoplasma penetrans is an emerging pathogen, recently described as a possible aeti…
View article: Association of clinicopathologic and molecular factors with the occurrence of positive margins in breast cancer
Association of clinicopathologic and molecular factors with the occurrence of positive margins in breast cancer Open
Purpose To explore the association of clinicopathologic and molecular factors with the occurrence of positive margins after first surgery in breast cancer. Methods The clinical and RNA-Seq data for 951 (75 positive and 876 negative margins…
View article: Impact of the progressive uptake of pneumococcal conjugate vaccines on the epidemiology and antimicrobial resistance of invasive pneumococcal disease in Gipuzkoa, northern Spain, 1998–2022
Impact of the progressive uptake of pneumococcal conjugate vaccines on the epidemiology and antimicrobial resistance of invasive pneumococcal disease in Gipuzkoa, northern Spain, 1998–2022 Open
Objectives To analyze the impact of pneumococcal conjugate vaccines (PCVs) on the incidence of invasive pneumococcal diseases (IPDs) and pneumococcal antibiotic resistance in Gipuzkoa, northern Spain for a 25 years period. Methods All case…
View article: Pressure-Enabled Drug Delivery (PEDD) of a class C TLR9 agonist in combination with checkpoint inhibitor therapy in a murine pancreatic cancer model
Pressure-Enabled Drug Delivery (PEDD) of a class C TLR9 agonist in combination with checkpoint inhibitor therapy in a murine pancreatic cancer model Open
Pressure-Enabled Drug Delivery of toll-like receptor 9 agonist by Pancreatic Retrograde Venous Infusion with systemic anti-programmed death receptor-1 demonstrated improved pancreatic ductal adenocarcinoma tumor control in a murine pancrea…
View article: Table of Contents (2 pgs)
Table of Contents (2 pgs) Open
View article: Data from Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model
Data from Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model Open
Irreversible electroporation (IRE) is a nonthermal ablation technique that is used clinically in selected patients with locally advanced pancreatic cancer, but most patients develop recurrent distant metastatic disease. We hypothesize that…
View article: List of KPC Peptides from Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model
List of KPC Peptides from Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model Open
List of KPC Peptides
View article: List of KPC Peptides from Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model
List of KPC Peptides from Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model Open
List of KPC Peptides
View article: Supplementary Figures and Tables from Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model
Supplementary Figures and Tables from Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model Open
Supplementary Figures 1-6 and Supplementary Tables 1 and 2.
View article: Data from Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model
Data from Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model Open
Irreversible electroporation (IRE) is a nonthermal ablation technique that is used clinically in selected patients with locally advanced pancreatic cancer, but most patients develop recurrent distant metastatic disease. We hypothesize that…
View article: Supplementary Figures and Tables from Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model
Supplementary Figures and Tables from Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model Open
Supplementary Figures 1-6 and Supplementary Tables 1 and 2.
View article: Carbon and Water Footprint Evaluation of 120Wp Rural Household Photovoltaic System: Case Study
Carbon and Water Footprint Evaluation of 120Wp Rural Household Photovoltaic System: Case Study Open
This study uses the Life Cycle Analysis (LCA) to evaluate the magnitude of the environmental impact, in terms of global warming potential, and water footprint throughout the 20 years of useful life of a rural electrical energy concession c…
View article: Cellular microRNAs correlate with clinical parameters in multiple injury patients
Cellular microRNAs correlate with clinical parameters in multiple injury patients Open
INTRODUCTION The pathophysiology of the inflammatory response after major trauma is complex, and the magnitude correlates with severity of tissue injury and outcomes. Study of infection-mediated immune pathways has demonstrated that cellul…
View article: Epidemiology and Clinical Features of Listeriosis in Gipuzkoa, Spain, 2010–2020
Epidemiology and Clinical Features of Listeriosis in Gipuzkoa, Spain, 2010–2020 Open
Background Listeriosis continues to be one of the most important notifiable foodborne diseases. Nonetheless, in Spain, there are few data on the molecular epidemiology of Listeria monocytogenes infections in recent years. Aim To describe c…
View article: Oxaliplatin-induced peripheral neuropathy can be minimized by pressurized regional intravascular delivery in an orthotopic murine pancreatic cancer model
Oxaliplatin-induced peripheral neuropathy can be minimized by pressurized regional intravascular delivery in an orthotopic murine pancreatic cancer model Open
Purpose There is a great need to reduce the toxicity of chemotherapy used in the management of pancreatic ductal adenocarcinoma (PDAC). Here we explore if regional pressurized delivery of oxaliplatin can minimize peripheral neuropathy in m…
View article: Tumor or Inflammatory Myofibroblastic Reaction in an Adolescent With an Abdominal Lymphatic Malformation?
Tumor or Inflammatory Myofibroblastic Reaction in an Adolescent With an Abdominal Lymphatic Malformation? Open
We report the case of a 17-year-old male who presented with intractable nausea and vomiting. Cross-sectional imaging revealed a large retrogastric abdominal mass. Fine needle aspiration done via endoscopic ultrasound (EUS) was nondiagnosti…
View article: The 2020 Pandemics: Lessons Learned in Academic Surgery and Beyond
The 2020 Pandemics: Lessons Learned in Academic Surgery and Beyond Open
View article: Oxaliplatin-Induced Peripheral Neuropathy Can Be Minimized By Pressurized Regional Intravascular Delivery In An Orthotopic Murine Pancreatic Cancer Model.
Oxaliplatin-Induced Peripheral Neuropathy Can Be Minimized By Pressurized Regional Intravascular Delivery In An Orthotopic Murine Pancreatic Cancer Model. Open
Purpose: There is a great need to reduce the toxicity of chemotherapy used in the management of pancreatic ductal adenocarcinoma (PDAC). Here we explore if regional pressurized delivery of oxaliplatin can minimize peripheral neuropathy in …
View article: Diagnostic accuracy of adenosine deaminase for pleural tuberculosis in a low prevalence setting: A machine learning approach within a 7-year prospective multi-center study
Diagnostic accuracy of adenosine deaminase for pleural tuberculosis in a low prevalence setting: A machine learning approach within a 7-year prospective multi-center study Open
Objective To analyze the performance of adenosine deaminase in pleural fluid combined with other parameters routinely measured in clinical practice and assisted by machine learning algorithms for the diagnosis of pleural tuberculosis in a …
View article: <i>Haemophilus influenzae</i> Type a Sequence Type 23, Northern Spain
<i>Haemophilus influenzae</i> Type a Sequence Type 23, Northern Spain Open
Two consecutive cases of Haemophilus influenzae type a sequence type 23 invasive infection in 2 children attending the same daycare in 2019 triggered epidemiologic surveillance of H. influenzae infections in northern Spain. Despite the inv…
View article: Multicenter evaluation of the Panbio™ COVID-19 rapid antigen-detection test for the diagnosis of SARS-CoV-2 infection
Multicenter evaluation of the Panbio™ COVID-19 rapid antigen-detection test for the diagnosis of SARS-CoV-2 infection Open
View article: Preparing Austere Maritime Surgical Teams for Deployment During the COVID-19 Global Pandemic: Is It Time to Change the Training Pipeline?
Preparing Austere Maritime Surgical Teams for Deployment During the COVID-19 Global Pandemic: Is It Time to Change the Training Pipeline? Open
Introduction Navy Medicine's Role 2 Light Maneuver (R2LM) Emergency Resuscitative Surgical Systems (ERSS) are austere surgical teams manned, trained, and equipped to provide life-saving damage control resuscitation and surgery in any envir…
View article: Measurement of Portal Vein Blood Circulating Tumor Cells is Safe and May Correlate With Outcomes in Resected Pancreatic Ductal Adenocarcinoma
Measurement of Portal Vein Blood Circulating Tumor Cells is Safe and May Correlate With Outcomes in Resected Pancreatic Ductal Adenocarcinoma Open
View article: U.S. Navy’s Response to a Shipboard Coronavirus Outbreak: Considerations for a Medical Management Plan at Sea
U.S. Navy’s Response to a Shipboard Coronavirus Outbreak: Considerations for a Medical Management Plan at Sea Open
View article: Azole resistance survey on clinical Aspergillus fumigatus isolates in Spain
Azole resistance survey on clinical Aspergillus fumigatus isolates in Spain Open
View article: Genomic Virulence Features of Two Novel Species Nocardia barduliensis sp. nov. and Nocardia gipuzkoensis sp. nov., Isolated from Patients with Chronic Pulmonary Diseases
Genomic Virulence Features of Two Novel Species Nocardia barduliensis sp. nov. and Nocardia gipuzkoensis sp. nov., Isolated from Patients with Chronic Pulmonary Diseases Open
Strains 335427T and 234509T, isolated from two 76-year-old patients with chronic pulmonary diseases, were the subject of polyphasic taxonomic studies and comparative genomic analyses for virulence factors. The 16 rRNA gene sequence similar…
View article: An Enlarging Hepatic Mass of Unknown Etiology
An Enlarging Hepatic Mass of Unknown Etiology Open
View article: COVID-19: Pandemic surgery guidance
COVID-19: Pandemic surgery guidance Open
Based on high quality surgery and scientific data, scientists and surgeons are committed to protecting patients as well as healthcare staff and hereby provide this Guidance to address the special issues circumstances related to the exponen…