Diego Cantarovich
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View article: Response to the Letter to the Editor Entitled “Refining Approaches to Fibrosis Control in Kidney Transplant Recipients”
Response to the Letter to the Editor Entitled “Refining Approaches to Fibrosis Control in Kidney Transplant Recipients” Open
View article: Is 2 h of Hypothermic Machine Perfusion for Pancreas Preservation Effective in Improving Graft Reperfusion?
Is 2 h of Hypothermic Machine Perfusion for Pancreas Preservation Effective in Improving Graft Reperfusion? Open
Background. Static cold storage (SCS) remains the standard method for organ preservation. The development of parenchymal edema during prolonged hypothermic machine perfusion (HMP) was a major barrier to the introduction of this technique f…
View article: Impact of Corticosteroid-Free Regimen on Interstitial Fibrosis Following Kidney Transplantation
Impact of Corticosteroid-Free Regimen on Interstitial Fibrosis Following Kidney Transplantation Open
Progression of IF during the first year following kidney transplantation was not inferior among patients without CS compared with patients with CS.
View article: Anti-TNFα as an Adjunctive Therapy in Pancreas and Kidney Transplantation
Anti-TNFα as an Adjunctive Therapy in Pancreas and Kidney Transplantation Open
The rate of early pancreas allograft failure remains high due to thrombosis but also to severity of rejection episodes. We investigated if adjunct anti-TNFα therapy was safe and could improve outcomes after pancreas transplantation. We inv…
View article: Early Determination of Tacrolimus Concentration–Dose Ratio Identifies Risk of Allograft Loss in Kidney Transplantation
Early Determination of Tacrolimus Concentration–Dose Ratio Identifies Risk of Allograft Loss in Kidney Transplantation Open
View article: Banff 2024 Pancreas Transplantation Report: Diagnosis and Impact of Chronic Active T-Cell Mediated Allograft Rejection, Re-Evaluation of the Indeterminate Category and Utilization of CD3/CD68 Immunostains in Biopsies with Ambiguous Findings
Banff 2024 Pancreas Transplantation Report: Diagnosis and Impact of Chronic Active T-Cell Mediated Allograft Rejection, Re-Evaluation of the Indeterminate Category and Utilization of CD3/CD68 Immunostains in Biopsies with Ambiguous Findings Open
View article: Impact of Hypothermic Perfusion on Immune Responses and Sterile Inflammation in a Preclinical Model of Pancreatic Transplantation
Impact of Hypothermic Perfusion on Immune Responses and Sterile Inflammation in a Preclinical Model of Pancreatic Transplantation Open
Background. In organ transplantation, cold ischemia is associated with sterile inflammation that subsequently conditions adaptive immunity directed against the grafts during revascularization. This inflammation is responsible for venous th…
View article: The role of donor hypertension and angiotensin II in the occurrence of early pancreas allograft thrombosis
The role of donor hypertension and angiotensin II in the occurrence of early pancreas allograft thrombosis Open
Background About 10–20% of pancreas allografts are still lost in the early postoperative period despite the identification of numerous detrimental risk factors that correlate with graft thrombosis. Methods We conducted a multicenter study …
View article: Belatacept in Pancreas Transplantation: Promising Insights From a Cohort Series
Belatacept in Pancreas Transplantation: Promising Insights From a Cohort Series Open
International audience
View article: Questions about the BEST-Fluids trial
Questions about the BEST-Fluids trial Open
View article: Primary Graft Function and 5 Year Insulin Independence After Pancreas and Islet Transplantation for Type 1 Diabetes: A Retrospective Parallel Cohort Study
Primary Graft Function and 5 Year Insulin Independence After Pancreas and Islet Transplantation for Type 1 Diabetes: A Retrospective Parallel Cohort Study Open
In islet transplantation (ITx), primary graft function (PGF) or beta cell function measured early after last infusion is closely associated with long term clinical outcomes. We investigated the association between PGF and 5 year insulin in…
View article: Banff 2022 pancreas transplantation multidisciplinary report: Refinement of guidelines for T cell–mediated rejection, antibody-mediated rejection and islet pathology. Assessment of duodenal cuff biopsies and noninvasive diagnostic methods
Banff 2022 pancreas transplantation multidisciplinary report: Refinement of guidelines for T cell–mediated rejection, antibody-mediated rejection and islet pathology. Assessment of duodenal cuff biopsies and noninvasive diagnostic methods Open
View article: Feasibility of manufacture of chimeric antigen receptor-regulatory T cells from patients with end-stage renal disease
Feasibility of manufacture of chimeric antigen receptor-regulatory T cells from patients with end-stage renal disease Open
Background Gene-modified cell therapy with regulatory T cells (Tregs) is a promising approach to prevent graft rejection and induce immunological tolerance in organ transplantation. We are developing a cell therapy comprising autologous na…
View article: Sterile Pancreas Inflammation during Preservation and after Transplantation
Sterile Pancreas Inflammation during Preservation and after Transplantation Open
The pancreas is very susceptible to ischemia-reperfusion injury. Early graft losses due to pancreatitis and thrombosis represent a major issue after pancreas transplantation. Sterile inflammation during organ procurement (during brain deat…
View article: Very Low Dose Anti-Thymocyte Globulins Versus Basiliximab in Non-Immunized Kidney Transplant Recipients
Very Low Dose Anti-Thymocyte Globulins Versus Basiliximab in Non-Immunized Kidney Transplant Recipients Open
The choice between Basiliximab (BSX) or Anti-Thymocyte Globulin (ATG) as induction therapy in non-immunized kidney transplant recipients remains uncertain. Whilst ATG may allow steroid withdrawal and a decrease in tacrolimus, it also incre…
View article: Banff 2022 Pancreas Transplantation Multidisciplinary Report: Refinement of Guidelines for TCMR, AMR, Islet and Non-Rejection Pathologies. Assessment of Duodenal Cuff Biopsies and Non-Invasive Diagnostic Methods
Banff 2022 Pancreas Transplantation Multidisciplinary Report: Refinement of Guidelines for TCMR, AMR, Islet and Non-Rejection Pathologies. Assessment of Duodenal Cuff Biopsies and Non-Invasive Diagnostic Methods Open
View article: COVID-19 Severity in Kidney Transplant Recipients According to Their Postvaccination Serological Assessment
COVID-19 Severity in Kidney Transplant Recipients According to Their Postvaccination Serological Assessment Open
View article: A fourth SARS-CoV-2 mRNA vaccine in strictly seronegative kidney transplant recipients
A fourth SARS-CoV-2 mRNA vaccine in strictly seronegative kidney transplant recipients Open
View article: Occurrence of De novo Donor-Specific Antibodies After COVID-19 in Kidney Transplant Recipients Is Low Despite Immunosuppression Modulation
Occurrence of De novo Donor-Specific Antibodies After COVID-19 in Kidney Transplant Recipients Is Low Despite Immunosuppression Modulation Open
The incidence of post-COVID-19 DSA among COVID-19-positive kidney transplant recipients was low (4%) despite a significant decrease in immunosuppression and was mainly restricted to high-risk immunologic patient's status. COVID-19 severity…
View article: Incidence, Risk Factors and Outcomes of Kidney and Liver Cyst Infection in Kidney Transplant Recipient With ADPKD
Incidence, Risk Factors and Outcomes of Kidney and Liver Cyst Infection in Kidney Transplant Recipient With ADPKD Open
View article: Une polykystose peut en cacher une autre. Il n’est jamais trop tard pour l’analyse génétique !
Une polykystose peut en cacher une autre. Il n’est jamais trop tard pour l’analyse génétique ! Open
In France, numerous patients suffered from chronic kidney disease on polycystic kidney disorder. If PKD1 and PKD2 inactivating mutations are the most prevalent, several other genetic polycystic kidney diseases are responsible for similar k…
View article: Observations on improving COVID-19 vaccination responses in kidney transplant recipients: heterologous vaccination and immunosuppression modulation
Observations on improving COVID-19 vaccination responses in kidney transplant recipients: heterologous vaccination and immunosuppression modulation Open
View article: Pancreas allograft rejection occurring after ChAdOx1 nCoV-19 vaccine
Pancreas allograft rejection occurring after ChAdOx1 nCoV-19 vaccine Open
View article: A third injection of the BNT162b2 mRNA COVID-19 vaccine in kidney transplant recipients improves the humoral immune response
A third injection of the BNT162b2 mRNA COVID-19 vaccine in kidney transplant recipients improves the humoral immune response Open
View article: Cohort study: “Outcomes of kidney transplantation in patients with prosthetic heart valves”
Cohort study: “Outcomes of kidney transplantation in patients with prosthetic heart valves” Open
The number of kidney transplant candidates with prosthetic heart valves (PHVs) is increasing. Yet, outcomes of kidney transplantation in these patients are still unclear. This is the first report of post-transplant outcomes in patients wit…
View article: Among CMV‐positive renal transplant patients receiving non‐T‐cell depleting induction, the absence of CMV disease prevention is a safe strategy: A retrospective cohort of 372 patients
Among CMV‐positive renal transplant patients receiving non‐T‐cell depleting induction, the absence of CMV disease prevention is a safe strategy: A retrospective cohort of 372 patients Open
Cytomegalovirus (CMV) is the most common opportunistic pathogen affecting renal transplant recipients, especially in the first months. CMV‐seropositive renal transplant recipients (CMV R+) are at intermediate risk for CMV disease, but this…
View article: Time-dependent lymphocyte count after transplantation is associated with higher risk of graft failure and death
Time-dependent lymphocyte count after transplantation is associated with higher risk of graft failure and death Open
View article: Kidney transplantation from extended-criteria donors: An increased risk of ureteral and urinary complications? Study from 10279 patients
Kidney transplantation from extended-criteria donors: An increased risk of ureteral and urinary complications? Study from 10279 patients Open
View article: Prognostic value for long-term graft survival of estimated glomerular filtration rate and proteinuria quantified at 3 months after kidney transplantation
Prognostic value for long-term graft survival of estimated glomerular filtration rate and proteinuria quantified at 3 months after kidney transplantation Open
Background The estimated glomerular filtration rate (eGFR) measured at 1 year is the usual benchmark applied in kidney transplantation (KT). However, acting on earlier eGFR values could help in managing KT during the first post-operative y…
View article: Tacrolimus- versus sirolimus-based immunosuppression after simultaneous pancreas and kidney transplantation: 5-year results of a randomized trial
Tacrolimus- versus sirolimus-based immunosuppression after simultaneous pancreas and kidney transplantation: 5-year results of a randomized trial Open