Diego Eidy Chiba
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View article: Synergistic Enhancement of 5-Fluorouracil Chemotherapeutic Efficacy by Taurine in Colon Cancer Rat Model
Synergistic Enhancement of 5-Fluorouracil Chemotherapeutic Efficacy by Taurine in Colon Cancer Rat Model Open
Colorectal cancer (CRC) is one of the top 10 most common cancers worldwide and caused approximately 10 million deaths in 2022. CRC mortality has increased by 10% since 2020 and 52.000 deaths will occur in 2024, highlighting the limitations…
View article: The preventive effect of Taurine in early stage of colon chemical carcinogenesis
The preventive effect of Taurine in early stage of colon chemical carcinogenesis Open
Colorectal cancer is one of the most common types of cancer in the world.The aberrant crypts foci are the first dysplastic alterations observed in colons in animal models and in human beings.Taurine is the most abundant semi-essential β-am…
View article: HIV latency reversal agents: A potential path for functional cure?
HIV latency reversal agents: A potential path for functional cure? Open
View article: Antiplatelet activity and TNF-α release inhibition of phthalimide derivatives useful to treat sickle cell anemia
Antiplatelet activity and TNF-α release inhibition of phthalimide derivatives useful to treat sickle cell anemia Open
View article: Kick and Kill Approach: How Far are we from HIV Cure?
Kick and Kill Approach: How Far are we from HIV Cure? Open
View article: Epigenetic Regulatory Mechanisms Induced by Resveratrol
Epigenetic Regulatory Mechanisms Induced by Resveratrol Open
Resveratrol (RVT) is one of the main natural compounds studied worldwide due to its potential therapeutic use in the treatment of many diseases, including cancer, diabetes, cardiovascular diseases, neurodegenerative diseases and metabolic …
View article: Unraveling the Anticancer Effect of Curcumin and Resveratrol
Unraveling the Anticancer Effect of Curcumin and Resveratrol Open
Resveratrol and curcumin are natural products with important therapeutic properties useful to treat several human diseases, including cancer. In the last years, the number of studies describing the effect of both polyphenols against cancer…
View article: The Prodrug Approach: A Successful Tool for Improving Drug Solubility
The Prodrug Approach: A Successful Tool for Improving Drug Solubility Open
Prodrug design is a widely known molecular modification strategy that aims to optimize the physicochemical and pharmacological properties of drugs to improve their solubility and pharmacokinetic features and decrease their toxicity. A lack…
View article: Síntese e avaliação biológica de novos compostos das séries LAPDESF FUR-PQ E LAPDESF FUR-TS contra Trypanosoma cruzi
Síntese e avaliação biológica de novos compostos das séries LAPDESF FUR-PQ E LAPDESF FUR-TS contra Trypanosoma cruzi Open