Diego Jaimes
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View article: Characterisation of nasopharyngeal colonisation by <i>Staphylococcus aureus</i> and the factors associated with colonisation in comorbid adults in a low- and middle-income country
Characterisation of nasopharyngeal colonisation by <i>Staphylococcus aureus</i> and the factors associated with colonisation in comorbid adults in a low- and middle-income country Open
Introduction Staphylococcus aureus is a major cause of pneumonia globally, with a particularly high burden in low- and middle-income countries (LMICs). Nasopharyngeal colonisation (NPC) by S. aureus plays a critical role in the pathogenesi…
View article: Sedatives and Opioids Best Practices: An Approach to the Use of Technological Tools
Sedatives and Opioids Best Practices: An Approach to the Use of Technological Tools Open
BACKGROUND: The formulation of opioid medications is becoming increasingly common among hospitalized patients, due to the need for pain control or sedation during procedures. This phenomenon represents the possibility of an increase in adv…
View article: Vancomycin Population Pharmacokinetic Models in Non- Critically Ill Adults Patients: a scoping review
Vancomycin Population Pharmacokinetic Models in Non- Critically Ill Adults Patients: a scoping review Open
Background Vancomycin is an effective first-line therapy primarily in methicillin-resistant Staphylococcus aureus (MRSA) infection and Clostridium difficile, however, it has been shown that its effectiveness and the reduction of nephrotoxi…
View article: The relation of nasopharyngeal colonization by Streptococcus pneumoniae in comorbid adults with unfavorable outcomes in a low-middle income country
The relation of nasopharyngeal colonization by Streptococcus pneumoniae in comorbid adults with unfavorable outcomes in a low-middle income country Open
Purpose Streptococcus pneumoniae (Spn ) is the primary bacterial cause of lower respiratory tract infections (LRTI) globally, particularly impacting older adults and children. While Spn colonization in children is linked to LRTI, its preva…
View article: Elevated Calprotectin Levels Reveal Loss of Vascular Pattern and Atrophy of Villi in Ileum by Digital Chromoendoscopy and Magnification Colonoscopy in Patients with Spondyloarthritis Without Having Inflammatory Bowel Disease
Elevated Calprotectin Levels Reveal Loss of Vascular Pattern and Atrophy of Villi in Ileum by Digital Chromoendoscopy and Magnification Colonoscopy in Patients with Spondyloarthritis Without Having Inflammatory Bowel Disease Open
Objective: This study aimed to establish a correlation between fecal calprotectin levels (FC) and intestinal inflammation in patients with spondyloarthritis without inflammatory bowel disease. Methods: A total of 180 SpA patients were incl…
View article: Assessment of Medication Adherence Using Mobile Applications in Chronic Obstructive Pulmonary Disease: A Scoping Review
Assessment of Medication Adherence Using Mobile Applications in Chronic Obstructive Pulmonary Disease: A Scoping Review Open
Chronic obstructive pulmonary disease (COPD) is a condition that significantly impacts both patients and healthcare systems. The management of COPD involves various pharmacological intervention strategies, and addressing the issue of low a…
View article: Assessment of Pharmacological Adherence Using Mobile Applications in Chronic Obstructive Pulmonary Disease: A Scoping Review
Assessment of Pharmacological Adherence Using Mobile Applications in Chronic Obstructive Pulmonary Disease: A Scoping Review Open
Chronic obstructive pulmonary disease (COPD) is a condition that significantly impacts both patients and healthcare systems. The management of COPD involves various pharmacological intervention strategies, and addressing the issue of low a…
View article: The Relation of Nasopharyngeal Colonization by Streptococcus pneumoniae in Comorbid Adults with Pneumonia and Unfavorable Outcomes in a Low-Middle Income Country
The Relation of Nasopharyngeal Colonization by Streptococcus pneumoniae in Comorbid Adults with Pneumonia and Unfavorable Outcomes in a Low-Middle Income Country Open
Purpose: Streptococcus pneumoniae (Spn) is the primary bacterial cause of lower respiratory tract infections (LRTI) globally, particularly impacting older adults and children. While Spn colonization in children is linked to LRTI, its preva…
View article: Estudio de microbiota fecal revela disbiosis específica en espondiloartritis, según subtipo, actividad de la enfermedad y tratamiento
Estudio de microbiota fecal revela disbiosis específica en espondiloartritis, según subtipo, actividad de la enfermedad y tratamiento Open
Introduction: Variability in microbiome composition and metabolic competence affects clinical activity and inflammatory status in spondyloarthritis-SpA. Aim: To compare the diversity and composition of the gastrointestinal microbiome of pa…
View article: 515 Implementation of a Translational Science Research Center in a high education level institution in Colombia - Latin America: Unisabana Center for Translational Science (UCTS)
515 Implementation of a Translational Science Research Center in a high education level institution in Colombia - Latin America: Unisabana Center for Translational Science (UCTS) Open
OBJECTIVES/GOALS: To establish and develop a high-level, dynamic, and self-sustainable Translational Science – research center in Colombia that promotes and articulates collaborative participation among different disciplines at Universidad…
View article: Streptococcus pneumoniae as a colonizing agent of the Nasopharynx - Oropharynx in adults: A systematic review and meta-analysis
Streptococcus pneumoniae as a colonizing agent of the Nasopharynx - Oropharynx in adults: A systematic review and meta-analysis Open
This study found a low prevalence of Spn NOC in adults. Notably, the prevalence of Spn NOC was higher in younger adults than in older adults. It is essential to highlight a significant heterogeneity among studies, which indicates there is …
View article: Efficacy of myofascial induction compared with its simulation on joint amplitude in people with axial spondylarthritis: Protocol of a randomized controlled clinical trial
Efficacy of myofascial induction compared with its simulation on joint amplitude in people with axial spondylarthritis: Protocol of a randomized controlled clinical trial Open
Background Axial spondyloarthritis (AxSpA) produces structural changes that cause alterations in body functions. One tissue that seems to have a predictive role in the etiology and progression of the disease is the soft tissue, particularl…
View article: Scoping review on population pharmacokinetics of vancomycin in non-critically ill
Scoping review on population pharmacokinetics of vancomycin in non-critically ill Open
Background : Vancomycin is an effective first-line therapy in MRSA infection, however, achieving an appropriate serum concentration is challenging. Population pharmacokinetics can assist the clinician in the selection of better regimen do…
View article: Oral manifestations associated with inflammatory bowel disease and early endoscopic findings in patients with spondyloarthritis
Oral manifestations associated with inflammatory bowel disease and early endoscopic findings in patients with spondyloarthritis Open
Background and aims Spondyloarthritis (SpA) is a group of autoinflammatory disorders, of which the primary extra-articular manifestation is inflammatory bowel disease (IBD). The oral cavity being a part of gastrointestinal tract, is signif…
View article: Estimation of the Difference in Colistin Plasma Levels in Critically Ill Patients with Favorable or Unfavorable Clinical Outcomes
Estimation of the Difference in Colistin Plasma Levels in Critically Ill Patients with Favorable or Unfavorable Clinical Outcomes Open
In recent decades, antimicrobial resistance (AMR) has led to an increased use of therapeutic alternatives. Among these options, colistin continues to be an option for the treatment of multi-resistant (MDR) Gram-negative bacterial infection…
View article: Impact on Antibiotic Resistance, Therapeutic Success, and Control of Side Effects in Therapeutic Drug Monitoring (TDM) of Daptomycin: A Scoping Review
Impact on Antibiotic Resistance, Therapeutic Success, and Control of Side Effects in Therapeutic Drug Monitoring (TDM) of Daptomycin: A Scoping Review Open
Antimicrobial resistance (AR) is a problem that threatens the search for adequate safe and effective antibiotic therapy against multi-resistant bacteria like methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant Ente…
View article: Clinical Evidence of Magistral Preparations Based on Medicinal Cannabis
Clinical Evidence of Magistral Preparations Based on Medicinal Cannabis Open
Cannabis has been widely used as a medicinal plant for millennia; however, studies related to its main components were first conducted in 1960. Subsequently, laboratories have produced new components and structures related to its active bi…
View article: Pharmacovigilance of Biopharmaceuticals in Rheumatic Diseases, Adverse Events, Evolution, and Perspective: An Overview
Pharmacovigilance of Biopharmaceuticals in Rheumatic Diseases, Adverse Events, Evolution, and Perspective: An Overview Open
Since we have gained an understanding of the immunological pathophysiology of rheumatic diseases such as rheumatoid arthritis and systemic lupus erythematosus, treatment based on biological drugs has become a fundamental axis. These therap…
View article: Is There a Role for the Therapeutic Drug Monitoring of Colistin? An Overview
Is There a Role for the Therapeutic Drug Monitoring of Colistin? An Overview Open
Colistin is used as a last-line antibiotic for the treatment of Gram-negative multiresistant bacteria. Due to its high nephrotoxicity, Therapeutic Drug Monitoring (TDM) is recommended for dose adjustment. We aimed to evaluate the available…
View article: Diagnostic utility of optical coherence tomography in patients with demyelinating optic neuritis
Diagnostic utility of optical coherence tomography in patients with demyelinating optic neuritis Open
6 páginas
View article: Label-Free Quantification of Anti-TNF-α in Patients Treated with Adalimumab Using an Optical Biosensor
Label-Free Quantification of Anti-TNF-α in Patients Treated with Adalimumab Using an Optical Biosensor Open
This study describes the development of an immunosensory label-free quantification methodology based on surface plasmon resonance (SPR) and its applicability in measuring/evaluating therapeutic drug monitoring (TDM) of anti-TNF-α monoclona…
View article: Associations of the Levels of C4d-bearing Reticulocytes and High-avidity Anti-dsDNA Antibodies with Disease Activity in Systemic Lupus Erythematosus
Associations of the Levels of C4d-bearing Reticulocytes and High-avidity Anti-dsDNA Antibodies with Disease Activity in Systemic Lupus Erythematosus Open
Objective. There are no laboratory tools that detect early flares in systemic lupus erythematosus (SLE). Our aim was to validate in our population the previous findings of the association of C4d-bearing reticulocytes (R-C4d) compared to an…
View article: May-Thurner syndrome as a differential diagnosis in recurrent thrombosis
May-Thurner syndrome as a differential diagnosis in recurrent thrombosis Open
4 páginas