David Jiménez
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View article: Right ventricular dysfunction on echocardiography to predict mortality in acute pulmonary embolism: an individual patient data meta-analysis
Right ventricular dysfunction on echocardiography to predict mortality in acute pulmonary embolism: an individual patient data meta-analysis Open
In acute PE patients, RVD parameters from echocardiography are associated with short-term all-cause and PE-related death. The combination of at least 2 RVD parameters identifies PE patients at an increased risk for death.
View article: Fine-grained auxiliary learning for real-world product recommendation
Fine-grained auxiliary learning for real-world product recommendation Open
Product recommendation is the task of recovering the closest items to a given query within a large product corpora. Generally, one can determine if top-ranked products are related to the query by applying a similarity threshold; exceeding …
A machine learning approach to identify patients at risk for long-term consequences after pulmonary embolism Open
Pulmonary embolism (PE) can result in long-term sequelae, such as post-PE syndrome, including persistent dyspnea and chronic thromboembolic pulmonary hypertension (CTEPH). Existing prediction tools for severe post-PE complications lack sen…
Variation in Venous Thromboembolism Outcomes Based on Primary Cancer Site Open
VTE and bleeding risks in cancer-associated thrombosis vary substantially by cancer site. These findings support a personalized approach to anticoagulation in cancer patients with VTE.
View article: Evaluation of microbial-derived metabolites in patients with acute pulmonary embolism: findings from the MICTEP study
Evaluation of microbial-derived metabolites in patients with acute pulmonary embolism: findings from the MICTEP study Open
Introduction Functional analysis of microbiome with microbial-derived metabolites (MDMs) has emerged as key for several inflammatory and cardiovascular diseases. However, the data on the relationship of pulmonary embolism (PE) to microbiom…
View article: Artificial Intelligence Methods for Diagnostic and Decision-Making Assistance in Chronic Wounds: A Systematic Review
Artificial Intelligence Methods for Diagnostic and Decision-Making Assistance in Chronic Wounds: A Systematic Review Open
Chronic wounds, which take over four weeks to heal, are a major global health issue linked to conditions such as diabetes, venous insufficiency, arterial diseases, and pressure ulcers. These wounds cause pain, reduce quality of life, and i…
View article: Treatment of Venous Thromboembolism with Edoxaban over 18 Months: Results from ETNA-VTE Europe
Treatment of Venous Thromboembolism with Edoxaban over 18 Months: Results from ETNA-VTE Europe Open
The benefits and risks of extending anticoagulant treatment beyond the first 3 to 6 months in patients with venous thromboembolism (VTE) in clinical practice are not well understood. ETNA-VTE Europe is a prospective, noninterventional, pos…
View article: Fibrous dysplasia coexisting with aneurysmal bone cyst in the skull base: A case report
Fibrous dysplasia coexisting with aneurysmal bone cyst in the skull base: A case report Open
The coexistence of fibrous dysplasia and aneurysmal bone cyst in the craniofacial region is extremely rare. This article presents a unique case involving the skull base, diagnosed using computed tomography and magnetic resonance. Imaging r…
View article: Prototypical Extreme Multi-label Classification with a Dynamic Margin Loss
Prototypical Extreme Multi-label Classification with a Dynamic Margin Loss Open
Extreme Multi-label Classification (XMC) methods predict relevant labels for a given query in an extremely large label space. Recent works in XMC address this problem using deep encoders that project text descriptions to an embedding space…
View article: Right ventricular-pulmonary artery coupling for prognostication in acute pulmonary embolism
Right ventricular-pulmonary artery coupling for prognostication in acute pulmonary embolism Open
Aims Acute pulmonary embolism (PE) increases pulmonary pressure and impair right ventricular (RV) function. Echocardiographic investigation can quantify this mismatch as the tricuspid annular plane systolic excursion (TAPSE) to pulmonary a…
View article: Rate of recurrence after discontinuing anticoagulation in patients with venous thromboembolism within 30 days after <scp>COVID</scp>‐19 vaccine
Rate of recurrence after discontinuing anticoagulation in patients with venous thromboembolism within 30 days after <span>COVID</span>‐19 vaccine Open
This study generated evidence to guide anticoagulation in patients with VTE after vaccination for COVID-19. We provided data on the low recurrence rate after cessation of anticoagulant therapy and the findings for this study offer timely i…
View article: Duration of anticoagulation of venous thromboembolism
Duration of anticoagulation of venous thromboembolism Open
Venous thromboembolism (VTE) is a common, serious condition that requires anticoagulation for at least three months to prevent recurrence and long-term complications. After this initial period, the decision to continue or stop anticoagulat…
View article: Author response: Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons
Author response: Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons Open
Large vesicle extrusion from neurons may contribute to spreading pathogenic protein aggregates and promoting inflammatory responses, two mechanisms leading to neurodegenerative disease. Factors that regulate extrusion of large vesicles, su…
View article: Reviewer #3 (Public Review): Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons
Reviewer #3 (Public Review): Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons Open
Large vesicle extrusion from neurons may contribute to spreading pathogenic protein aggregates and promoting inflammatory responses, two mechanisms leading to neurodegenerative disease. Factors that regulate extrusion of large vesicles, su…
View article: Outpatient management of cancer-associated pulmonary embolism: A post-hoc analysis from the HOME-PE trial
Outpatient management of cancer-associated pulmonary embolism: A post-hoc analysis from the HOME-PE trial Open
Among patients treated at home, active cancer was a risk factor for complications, but among patients with active cancer, home treatment was not associated with adverse outcomes.
View article: Lung Cancer Related Thrombosis (LCART): Focus on Immune Checkpoint Blockade
Lung Cancer Related Thrombosis (LCART): Focus on Immune Checkpoint Blockade Open
Cancer-associated thrombosis (CAT) is a common complication in lung cancer patients. Lung cancer confers an increased risk of thrombosis compared to other solid malignancies across all stages of the disease. Newer treatment agents, includi…
View article: Validation of Echocardiographic Measurements in Patients with Pulmonary Embolism in the RIETE Registry
Validation of Echocardiographic Measurements in Patients with Pulmonary Embolism in the RIETE Registry Open
Background In acute pulmonary embolism (PE), echocardiographic identification of right ventricular (RV) dysfunction will inform prognostication and clinical decision-making. Registro Informatizado Enfermedad TromboEmbolica (RIETE) is the w…
View article: Versatile Applications of Cyanoacetic Acid in Organic Chemistry: Active Methylene Compound for the Knoevenagel Condensation and Organocatalyst for the Biginelli Reaction
Versatile Applications of Cyanoacetic Acid in Organic Chemistry: Active Methylene Compound for the Knoevenagel Condensation and Organocatalyst for the Biginelli Reaction Open
The application of cyanoacetic acid as a catalyst for the Biginelli reaction and as an active methylene compound for the Knoevenagel condensation reaction was evaluated. Using cyanoacetic acid as a Bronsted acid catalyst, after a synthetic…
View article: Leadership skills assessment in technical-vocational institution management
Leadership skills assessment in technical-vocational institution management Open
With numerous challenges for leaders of educational institutions, it is important to identify and develop the necessary skills for a leader to bring one's organization to fulfill its mission, vision and objectives for success. This study i…
View article: High-Sensitivity vs Conventional Troponin Cutoffs for Risk Stratification in Patients With Acute Pulmonary Embolism
High-Sensitivity vs Conventional Troponin Cutoffs for Risk Stratification in Patients With Acute Pulmonary Embolism Open
Importance High-sensitivity troponin tests can detect even milder cardiac troponin elevations in plasma, beyond the threshold of conventional troponin tests. Whether detection of low-grade cardiac troponin elevation is associated with outc…
View article: Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons
Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons Open
Large vesicle extrusion from neurons may contribute to spreading pathogenic protein aggregates and promoting inflammatory responses, two mechanisms leading to neurodegenerative disease. Factors that regulate extrusion of large vesicles, su…
View article: OC 40.3 High-Sensitivity Versus Conventional Troponin Cutoffs for Risk Stratification in Patients with Hemodynamically-Stable Acute Pulmonary Embolism
OC 40.3 High-Sensitivity Versus Conventional Troponin Cutoffs for Risk Stratification in Patients with Hemodynamically-Stable Acute Pulmonary Embolism Open
Table 2: Diagnostic flow of 12,365 patients with suspected DVT under modified algorithm Conclusion(s):The modified algorithm can detect the vast majority of DVTs and maintain a low rate of missed DVTs, whilst very significantly reducing th…