Diego Romano Perinelli
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View article: A.A.A. Good Wines WANTED: Blockchain, Non-Destructive Ultrasonic Techniques and Soil Health Assessment for Wine Traceability
A.A.A. Good Wines WANTED: Blockchain, Non-Destructive Ultrasonic Techniques and Soil Health Assessment for Wine Traceability Open
The wine industry faces increasing challenges related to authenticity, safety, and sustainability due to recurrent fraud, shifting consumer preferences, and environmental concerns. In this study, as part of the B.I.O.C.E.R.T.O project, we …
View article: Hydrogels Powered by Nanoemulsion Technology for the Topical Delivery of Acmella oleracea Extract
Hydrogels Powered by Nanoemulsion Technology for the Topical Delivery of Acmella oleracea Extract Open
Background/Objectives: Natural products are gaining increasing importance due to the large variety of biological activities exerted by their constituents. Among these, the products deriving from Acmella oleracea (L.) R.K. Jansen can be exp…
View article: Exploring the Functional Properties of Hydrolyzed Keratin: Filling the Knowledge Gap on Surface Active, Emulsifying, and Thickening Properties
Exploring the Functional Properties of Hydrolyzed Keratin: Filling the Knowledge Gap on Surface Active, Emulsifying, and Thickening Properties Open
Hydrolyzed keratin (HK) refers to any hydrolysate of keratin of a different origin derived by acid, alkali, enzymatic, or other methods of hydrolysis. HK is water soluble and has distinct chemical-physical properties compared to fibrous ke…
View article: A.A.A. Good Wines WANTED: Blockchain, Non-Destructive Ultrasonic Techniques and Soil Health Assessment for Wine Traceability
A.A.A. Good Wines WANTED: Blockchain, Non-Destructive Ultrasonic Techniques and Soil Health Assessment for Wine Traceability Open
The wine industry faces increasing challenges related to authenticity, safety, and sustainability due to recurrent fraud, shifting consumer preferences, and environmental concerns. In this study, part of the B.I.O.C.E.R.T.O project, we int…
View article: Toward the Optimal Choice of Gelled Vehicles for Oral Drug Administration in Dysphagic Patients
Toward the Optimal Choice of Gelled Vehicles for Oral Drug Administration in Dysphagic Patients Open
Background/Objectives: Thickened waters are commonly used for dysphagic patients to ensure hydration, facilitate safer swallowing, and administer oral therapies, yet their impact on drug dissolution remains unclear. This study aims to inve…
View article: Cluster aggregation of water-based deep eutectic solvents in water and evaluation of their cytotoxicity
Cluster aggregation of water-based deep eutectic solvents in water and evaluation of their cytotoxicity Open
Deep Eutectic Solvents (DESs) are emerging in the recent literature as promising environmentally friendly liquids in different topics, finding fruitful applications as substitutes to common volatile organic solvents. In this work a study o…
View article: Targeting Xylella fastidiosa: Sustainable management of Philaenus spumarius using carlina oxide
Targeting Xylella fastidiosa: Sustainable management of Philaenus spumarius using carlina oxide Open
Xylella fastidiosa Wells, a bacterial plant pathogen, represents a threat to many crops all around the word. Unfortunately, no effective treatments are available to reduce the infection and, to date, the most promising strategy relies on c…
View article: Unveiling the Performance of Co-Assembled Hybrid Nanocarriers: Moving towards the Formation of a Multifunctional Lipid/Random Copolymer Nanoplatform
Unveiling the Performance of Co-Assembled Hybrid Nanocarriers: Moving towards the Formation of a Multifunctional Lipid/Random Copolymer Nanoplatform Open
Despite the appealing properties of random copolymers, the use of these biomaterials in association with phospholipids is still limited, as several aspects of their performance have not been investigated. The aim of this work is the formul…
View article: CLUSTER AGGREGATION OF WATER-BASED DEEP EUTECTIC SOLVENTS IN WATER AND EVALUATION OF THEIR CYTOTOXICITY
CLUSTER AGGREGATION OF WATER-BASED DEEP EUTECTIC SOLVENTS IN WATER AND EVALUATION OF THEIR CYTOTOXICITY Open
Deep Eutectic Solvents (DESs) are emerging in the recent literature as promising environmentally friendly liquids in different topics, finding fruitful applications as substitutes to common volatile organic solvents. These mixtures are pre…
View article: Deciphering the Lipid-Random Copolymer Interactions and Encoding Their Properties to Design a Hybrid System
Deciphering the Lipid-Random Copolymer Interactions and Encoding Their Properties to Design a Hybrid System Open
Lipid/copolymer colloidal systems are deemed hybrid materials with unique properties and functionalities. Their hybrid nature leads to complex interfacial phenomena, which have not been fully encoded yet, navigating their properties. Movin…
View article: Exploring Immersion Coating as a Cost-Effective Method for Small-Scale Production of Enteric-Coated Gelatin Capsules
Exploring Immersion Coating as a Cost-Effective Method for Small-Scale Production of Enteric-Coated Gelatin Capsules Open
The coating process for solid dosage forms is widely used in the pharmaceutical industry but presents challenges for small-scale production, needed in personalized medicine and clinical or galenic settings. This study aimed to evaluate imm…
View article: Enteral Delivery of Pravastatin Sodium Tablets: Effect of Compounding into a Liquid Form and Co-Administration of Enteral Nutrition
Enteral Delivery of Pravastatin Sodium Tablets: Effect of Compounding into a Liquid Form and Co-Administration of Enteral Nutrition Open
Background: Compounding solid oral dosage forms into liquid preparations is a common practice for administering drug therapy to patients with swallowing difficulties. This is particularly relevant for those on enteral nutrition, where fact…
View article: Fabricating Polymer/Surfactant/Cyclodextrin Hybrid Particles for Possible Nose-to-Brain Delivery of Ropinirole Hydrochloride: In Vitro and Ex Vivo Evaluation
Fabricating Polymer/Surfactant/Cyclodextrin Hybrid Particles for Possible Nose-to-Brain Delivery of Ropinirole Hydrochloride: In Vitro and Ex Vivo Evaluation Open
Ropinirole is a non-ergolinic dopamine agonist used to manage Parkinson’s disease and it is characterized by poor oral bioavailability. This study aimed to design and develop advanced drug delivery systems composed of poloxamer 407, a non-…
View article: PEO-<i>b</i>-PCL/Tween 80/cyclodextrin systems: from bioinspired fabrication to possible nasal administration of ropinirole hydrochloride
PEO-<i>b</i>-PCL/Tween 80/cyclodextrin systems: from bioinspired fabrication to possible nasal administration of ropinirole hydrochloride Open
Hybrid PEO- b -PCL/Tween 80/cyclodextrin systems: physicochemical and morphological characterization, and in vitro release studies.
View article: Toxicity and repellent activity of a carlina oxide nanoemulsion toward the South American tomato pinworm, Tuta absoluta
Toxicity and repellent activity of a carlina oxide nanoemulsion toward the South American tomato pinworm, Tuta absoluta Open
Plant essential oil (EO)-based insecticides represent a promising tool for IPM, though their formulation is limited by poor physio-chemical properties. EO encapsulation into stable formulations, like nano emulsions (NEs), could boost EO ef…
View article: Sugar-Based Monoester Surfactants: Synthetic Methodologies, Properties, and Biological Activities
Sugar-Based Monoester Surfactants: Synthetic Methodologies, Properties, and Biological Activities Open
Glycolipids are biocompatible and biodegradable amphiphilic compounds characterized by a great scientific interest for their potential applications in various technological areas, including pharmaceuticals, cosmetics, agriculture, and food…
View article: Small-Angle X-ray Scattering Unveils the Internal Structure of Lipid Nanoparticles
Small-Angle X-ray Scattering Unveils the Internal Structure of Lipid Nanoparticles Open
Lipid nanoparticles own a remarkable potential in nanomedicine, only partially disclosed. While the clinical use of liposomes and cationic lipid-nucleic acid complexes is well-established, liquid lipid nanoparticles (nanoemulsions), solid …
View article: Inulin Functionalized “Giuncata” Cheese as a Source of Prebiotic Fibers
Inulin Functionalized “Giuncata” Cheese as a Source of Prebiotic Fibers Open
The development of functional foods in the dairy sector represents a flourishing field of technological research. In this study, an Italian fresh cheese as “giuncata” was enriched with inulin, a dietary fiber, with the aim of developing a …
View article: Quantification of Squalene and Lactic Acid in Hair Bulbs with Damaged Sheaths: Are They Metabolic Wastes in Alopecia?
Quantification of Squalene and Lactic Acid in Hair Bulbs with Damaged Sheaths: Are They Metabolic Wastes in Alopecia? Open
Alopecia is a pathological and multifactorial condition characterised by an altered hair growth cycle and ascribed to different pathogenic causes. Cell energetic imbalances in hair follicles occurring in this disorder could lead to the pro…
View article: Encapsulation of Hemp (Cannabis sativa L.) Essential Oils into Nanoemulsions for Potential Therapeutic Applications: Assessment of Cytotoxicological Profiles
Encapsulation of Hemp (Cannabis sativa L.) Essential Oils into Nanoemulsions for Potential Therapeutic Applications: Assessment of Cytotoxicological Profiles Open
Industrial hemp (Cannabis sativa L.), due to its bioactive compounds (terpenes and cannabinoids), has gained increasing interest in different fields, including for medical purposes. The evaluation of the safety profile of hemp essential oi…
View article: Encapsulation of Hemp (Cannabis sativa L.) Essential Oils into Nanoemulsions for Potential Therapeutic Applications: Assessment of Cytotoxicological Profile
Encapsulation of Hemp (Cannabis sativa L.) Essential Oils into Nanoemulsions for Potential Therapeutic Applications: Assessment of Cytotoxicological Profile Open
Industrial hemp (Cannabis sativa L.), due to its bioactive compounds (terpenes and cannabinoids), has gained an increasing interest in different fields, including medical purposes. The evaluation of the safety profile of hemp essential oil…
View article: Sodium lauryl sulfate as lubricant in tablets formulations: Is it worth?
Sodium lauryl sulfate as lubricant in tablets formulations: Is it worth? Open
Lubricants are excipients used in tablet formulations to reduce friction and adhesion forces within the die or on the punches surface during the manufacturing process. Despite these excipients are always required for the tablets production…
View article: Editorial: Innovative approaches in drug discovery and development
Editorial: Innovative approaches in drug discovery and development Open
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View article: Role of plant essential oil nanoemulsions on host colonization by the invasive ambrosia beetle Xylosandrus compactus
Role of plant essential oil nanoemulsions on host colonization by the invasive ambrosia beetle Xylosandrus compactus Open
The development of effective control strategies targeting non-native ambrosia beetles (Coleoptera: Curculionidae: Scolytinae and Platypodinae) represents an emerging challenge. This is due both to their rapid spread into climatically suita…