Dilek Gogaş Yavuz
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View article: The Relationship Between Acromegaly and Hepatic Steatosis: Insights from FibroScan Imaging
The Relationship Between Acromegaly and Hepatic Steatosis: Insights from FibroScan Imaging Open
Purpose: The relationship between metabolic dysfunction-associated steatotic liver disease (MASLD) and acromegaly is unclear due to the complex metabolic effects of growth hormone (GH). GH stimulates gluconeogenesis, glycogenolysis, and li…
View article: Best practice recommendations for the diagnosis and management of hypoparathyroidism
Best practice recommendations for the diagnosis and management of hypoparathyroidism Open
These best practice recommendations provide a framework for HypoPT diagnosis and management, emphasizing individualized care, role of DNA analysis in the diagnosis of nonsurgical HypoPT, and role of PTH or PTH analogue therapy as appropria…
View article: Evaluation of the clinical pharmacist’s effect on achieving treatment goals in patients with hypothyroidism: a randomized controlled trial
Evaluation of the clinical pharmacist’s effect on achieving treatment goals in patients with hypothyroidism: a randomized controlled trial Open
This study protocol has been retrospectively registered at ClinicalTrials.gov (NCT06408909) at 06/05/2024.
View article: The Impact of Obesity-Related Complications on Healthcare Costs – Outcomes of a Pharmacoeconomic Weight Loss Model
The Impact of Obesity-Related Complications on Healthcare Costs – Outcomes of a Pharmacoeconomic Weight Loss Model Open
The current pharmacoeconomic model indicated that complications were the major cost drivers in obesity. Weight loss dramatically reduced healthcare expenditures in obese patients, and T2DM was the leading cause in all age groups.
View article: The cause of perioperative hypersensitivity in adults and consequences of subsequent anesthesia
The cause of perioperative hypersensitivity in adults and consequences of subsequent anesthesia Open
Background: In the perioperative period, patients are exposed to many agents that may cause hypersensitivity reaction; so, finding the culprit drug is important for patient safety in the event of the need for repeat anesthesia. Aim: Our ai…
View article: P-19 A PATIENT WITH ATYPICAL PARATHYROID ADENOMA
P-19 A PATIENT WITH ATYPICAL PARATHYROID ADENOMA Open
Introduction Primary hyperparathyroidism is most frequently caused by a parathyroid adenoma, occasionally by parathyroid hyperplasia, rarely by atypical parathyroid adenoma and parathyroid carcinoma. Here, we present a case diagnosed as PH…
View article: P-10 CUSHING'S SYNDROME WITH ATYPICAL ADRENAL MASS AND ELEVATED 17-HYDROXYPROGESTERONE: A DIAGNOSTIC CHALLENGE
P-10 CUSHING'S SYNDROME WITH ATYPICAL ADRENAL MASS AND ELEVATED 17-HYDROXYPROGESTERONE: A DIAGNOSTIC CHALLENGE Open
Introduction Adrenal tumors can be challenging to diagnose, especially when they present with unusual biochemical profiles and unclear pathological findings. This case focuses on the management complexities of a patient with a heterogeneou…
View article: P-66 A INSTANCE OF PAPILLARY THYROID CANCER MANIFESTED WITH SCAPULAR METASTASIS
P-66 A INSTANCE OF PAPILLARY THYROID CANCER MANIFESTED WITH SCAPULAR METASTASIS Open
Introduction Bone metastasis of well differentiated thyroid tumors observed in 2% and 13% of the patients. Bone metastasis usually occurs mostly in spine, but also in extremities, rib cage and pelvic bones. Here we present a case different…
View article: P-18 THREE BODY PROBLEM PATIENT: EHLER DANLOS SYNDROME COMBINED WITH HYPOPHOSPHATASIA AND FATTY ACID OXIDATION DEFECT
P-18 THREE BODY PROBLEM PATIENT: EHLER DANLOS SYNDROME COMBINED WITH HYPOPHOSPHATASIA AND FATTY ACID OXIDATION DEFECT Open
Introduction Ehler-Danlos syndrome (EDS) is a genetic disorder that affects connective tissues, including the skin, joints, and blood vessel walls. EDS can be accompanied by postural tachycardia syndrome, acid reflux, mast cell activation …
View article: O-16 A CASE OF VITAMIN D-DEPENDENT RICKETS DIAGNOSED IN ADULTHOOD FOLLOWING PREGNANCY
O-16 A CASE OF VITAMIN D-DEPENDENT RICKETS DIAGNOSED IN ADULTHOOD FOLLOWING PREGNANCY Open
Discussion Vitamin-D (Vit-D)-dependent rickets are the result of a deficiency in 1-alpha hydroxylase. It is a rare condition that is typically diagnosed in childhood. We present a case of Vit-D-dependent rickets that was detected in adulth…
View article: Annual Health Expenditures by Body Mass Index Categories and the Economic Impact of Obesity in Türkiye: A Retrospective Modeling Study
Annual Health Expenditures by Body Mass Index Categories and the Economic Impact of Obesity in Türkiye: A Retrospective Modeling Study Open
Introduction: Obesity is considered not only a public health issue on a global scale but also a disease adversely affecting the world economies. Economic impact of overweight and obesity has not yet been investigated in Türkiye at a nation…
View article: The significance of finerenone as a novel therapeutic option in diabetic kidney disease: a scoping review with emphasis on cardiorenal outcomes of the finerenone phase 3 trials
The significance of finerenone as a novel therapeutic option in diabetic kidney disease: a scoping review with emphasis on cardiorenal outcomes of the finerenone phase 3 trials Open
This scoping review prepared by endocrinology and nephrology experts aimed to address the significance of finerenone, as a novel therapeutic option, in diabetic kidney disease (DKD), based on the biological prospect of cardiorenal benefit …
View article: Bone mineral density in patients with Cushing’s syndrome
Bone mineral density in patients with Cushing’s syndrome Open
Objective: Cushing’s syndrome is caused by the excessive secretion of cortisol or the intake of exogenous cortisol. Morbidity caused by osteoporosis is a major complication that cannot be ignored. We conducted a study to evaluate bone dens…
View article: The Economic Impact of Obesity in Turkey: A Micro-Costing Analysis
The Economic Impact of Obesity in Turkey: A Micro-Costing Analysis Open
Our findings confirm that obesity and its complications result in significant financial burden to the public healthcare system. By quantifying the burden of obesity across a comprehensive spectrum of ORCs, our study aims to support the eco…
View article: Prevalence of vitamin D deficiency and hypervitaminosis D among adult patients admitted to the tertiary care hospitals in Turkey
Prevalence of vitamin D deficiency and hypervitaminosis D among adult patients admitted to the tertiary care hospitals in Turkey Open
Purpose: Vitamin D deficiency is a common health problem around the world. This study aimed to evaluate the nationwide prevalence of vitamin D status in tertiary care hospitals in Turkey. Methods: Retrospectively, the data of vitamin D lev…
View article: P-83 Primary thyroid lymphoma presented with hypercalcemia and rapidly growing neck mass
P-83 Primary thyroid lymphoma presented with hypercalcemia and rapidly growing neck mass Open
Introduction Primary thyroid lymphoma is an uncommon malignancy, accounting for 1% to 2% of extranodal lymphomas and 1% to 5% of thyroid malignancies. Large B-cell lymphoma is the most prevalent form of primary thyroid lymphoma. Here, we p…
View article: P-33 A rare form of diabetes: MELAS
P-33 A rare form of diabetes: MELAS Open
Introduction MELAS (mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes) is a fatal multisystemic condition caused by a mitochondrial DNA mutation, the most prevalent is m.3243AAG. Diagnosis is common at a young age,and…
View article: P-82 Riedel's thyroiditis: three-year follow-up under steroid, rituximab and mycophenolate mofetil treatment
P-82 Riedel's thyroiditis: three-year follow-up under steroid, rituximab and mycophenolate mofetil treatment Open
Introduction Riedel's thyroiditis (RT) is an uncommon thyroiditis characterized by fibrosis, macrophage, and eosinophil infiltration and is assumed to be the primary cause of autoimmunity in the pathogenesis. Invasion of the surrounding ti…
View article: P-14 A case of Paget's disease of bone presenting at early stages of life
P-14 A case of Paget's disease of bone presenting at early stages of life Open
Paget's disease of bone is the metabolic bone disease that affects 2-4% of individuals over age 55 in European nations. The disease may be asymptomatic and can be detected incidentally through x-rays or biochemical tests conducted for anot…
View article: P-32 A Seckel syndrome patient exhibited with metabolic problems
P-32 A Seckel syndrome patient exhibited with metabolic problems Open
Introduction Seckel syndrome is a disease with nine distinct phenotypes that is inherited autosomally recessively and is caused by DNA damage on chromosomes 3, 13, and 18. It is also known as 'bird-headed dwarfism' due to the disease's cha…
View article: P-19 A case of Birt Hogg Dube syndrome presented with parathyroid carcinoma
P-19 A case of Birt Hogg Dube syndrome presented with parathyroid carcinoma Open
Introduction The Birt Hogg Dube syndrome is an autosomal dominant genodermatosis caused by a mutation in the folliculin gene. It is characterized by benign lung cysts with spontaneous pneumothorax, kidney tumors, and hair follicle tumors. …
View article: P-18 Dent's Disease as a rare cause of rickets
P-18 Dent's Disease as a rare cause of rickets Open
Introduction Dent's disease is a rare recessive X-linked disorder characterized by hypophosphatemia, hematuria, proteinuria, hypercalciuria, nephrocalcinosis, and progressive renal failure. The majority of cases are caused by mutations in …
View article: P-73 A case of malignant struma ovary
P-73 A case of malignant struma ovary Open
Introduction Germ cell malignancies originate from primordial gonadal and infrequently extragonadal germ cells. Germ cell tumors account for approximately 15–20% of all ovarian neoplasms, of which only 2% to 3% are malignant. Teratomas mak…
View article: Long-term efficacy and safety of subcutaneous pasireotide alone or in combination with cabergoline in Cushing’s disease
Long-term efficacy and safety of subcutaneous pasireotide alone or in combination with cabergoline in Cushing’s disease Open
Objective This study evaluated short- and long-term efficacy and safety of the second-generation somatostatin receptor ligand pasireotide alone or in combination with dopamine agonist cabergoline in patients with Cushing’s disease (CD). St…
View article: The Effect of Vitamin D Treatment on Advanced Glycation End-Products in Patients with Prediabetes and Type 2 Diabetes Mellitus
The Effect of Vitamin D Treatment on Advanced Glycation End-Products in Patients with Prediabetes and Type 2 Diabetes Mellitus Open
Objective: The aim of this study was to investigate the role of vitamin D replacement therapy on advanced glycation end-products in prediabetes and type 2 diabetes mellitus patients with vitamin D deficiency. Methods: One hundred twenty su…
View article: Does total tumour diameter, multifocality, number of tumour foci, or laterality predict lymph node metastasis or recurrence in differentiated thyroid cancer?
Does total tumour diameter, multifocality, number of tumour foci, or laterality predict lymph node metastasis or recurrence in differentiated thyroid cancer? Open
MTD and TTD increase the risk of LNM but not the recurrence in PTC. TTD, multifocality, and bilaterality can be considered risk factors in PTC staging systems and risk calculators.
View article: Progressive height increase in an adult patient: Aromatase Deficiency
Progressive height increase in an adult patient: Aromatase Deficiency Open
Introduction Aromatase deficiency (AD) is a rare autosomal recessive disease in that androgens are not converted into estrogens due to the CYP19A1 gene mutation. As estrogen deficiency is predominant, it is easier to diagnose females prese…
View article: A rare reason for hospital admission with muscle weakness in the Covid-19 rra: CPT-2 deficiency
A rare reason for hospital admission with muscle weakness in the Covid-19 rra: CPT-2 deficiency Open
Introduction Carnitine Palmitoyl Transferase-2 (CPT-2) is a mitochondrial enzyme involved in the pathway of long chain fatty acids. CPT-2 deficiency is a rare autosomal recessive disease. Except for neonatal and severe infantile hepatocard…