Dillan Saunders
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View article: fgf8a signalling shapes brain divergence between Malawi cichlids
fgf8a signalling shapes brain divergence between Malawi cichlids Open
Brain diversification is intimately linked with adaptive radiations, yet the underlying molecular basis remains poorly understood. Here, we examine the mechanisms of neural evolution in two ecologically divergent Lake Malawi cichlid specie…
View article: Spinal cord elongation enables proportional regulation of the zebrafish posterior body
Spinal cord elongation enables proportional regulation of the zebrafish posterior body Open
Early embryos display a remarkable ability to regulate tissue patterning in response to changes in tissue size. However, it is not clear whether this ability continues into post-gastrulation stages. Here, we performed targeted removal of d…
View article: Approximated gene expression trajectories for gene regulatory network inference on cell tracks
Approximated gene expression trajectories for gene regulatory network inference on cell tracks Open
View article: Insights into digit evolution from a fate map study of the forearm using <i>Chameleon</i>, a new transgenic chicken line
Insights into digit evolution from a fate map study of the forearm using <i>Chameleon</i>, a new transgenic chicken line Open
The cellular and genetic networks that contribute to the development of the zeugopod (radius and ulna of the forearm, tibia and fibula of the leg) are not well understood, although these bones are susceptible to loss in congenital human sy…
View article: Spinal Cord Elongation Enables Proportional Regulation of the Zebrafish Posterior Body
Spinal Cord Elongation Enables Proportional Regulation of the Zebrafish Posterior Body Open
Early embryos display a remarkable ability to regulate the patterning of tissues in response to changes in tissue size. However, it is not clear whether this ability continues into post-gastrulation stages upon cell commitment to distinct …
View article: Approximated Gene Expression Trajectories (AGETs) for Gene Regulatory Network Inference on Cell Tracks
Approximated Gene Expression Trajectories (AGETs) for Gene Regulatory Network Inference on Cell Tracks Open
View article: Insights into Digit Evolution from a Fate Map Study of the Forearm
Insights into Digit Evolution from a Fate Map Study of the Forearm Open
The cellular and genetic networks which contribute to the development of the zeugopod, (radius and ulna of the forearm, tibia and fibula of the leg) are not well understood, although these bones are susceptible to loss in congenital human …
View article: Quantitative Experimental Embryology: A Modern Classical Approach
Quantitative Experimental Embryology: A Modern Classical Approach Open
Experimental Embryology is often referred to as a classical approach of developmental biology that has been to some extent replaced by the introduction of molecular biology and genetic techniques to the field. Inspired by the combination o…
View article: Zebrafish neuromesodermal progenitors undergo a critical state transition in vivo
Zebrafish neuromesodermal progenitors undergo a critical state transition in vivo Open
View article: Zebrafish Neuromesodermal Progenitors Undergo a Critical State Transition <i>in vivo</i>
Zebrafish Neuromesodermal Progenitors Undergo a Critical State Transition <i>in vivo</i> Open
Summary The transition state model of cell differentiation proposes that a transient window of gene expression stochasticity precedes entry into a differentiated state. As this has been assessed primarily in vitro , we sought to explore wh…
View article: Approximated Gene Expression Trajectories (AGETs) for Gene Regulatory Network Inference on Cell Tracks
Approximated Gene Expression Trajectories (AGETs) for Gene Regulatory Network Inference on Cell Tracks Open
The study of pattern formation has greatly benefited from our ability to reverse-engineer gene regulatory network (GRN) structure from spatio-temporal quantitative gene expression data. Traditional approaches omit tissue morphogenesis, and…
View article: Zebrafish Neuromesodermal Progenitors Undergo a Critical State Transition <i>in vivo</i>
Zebrafish Neuromesodermal Progenitors Undergo a Critical State Transition <i>in vivo</i> Open
View article: Building consensus in neuromesodermal research: Current advances and future biomedical perspectives
Building consensus in neuromesodermal research: Current advances and future biomedical perspectives Open