Dimitrios Kazantzis
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View article: Macular Choroidal Thickness in Keratoconus: Systematic Review and Meta-Analysis of Current Evidence
Macular Choroidal Thickness in Keratoconus: Systematic Review and Meta-Analysis of Current Evidence Open
Background/Objectives: This study aimed to investigate changes and synthesize the existing evidence in macular choroidal thickness in patients with keratoconus (KC) compared to healthy controls, utilizing optical coherence tomography (OCT)…
View article: Using adaptive optics to assess hyporeflective clump speed and size in age-related macular degeneration in the PINNACLE Study. (PINNACLE Study Report 6)
Using adaptive optics to assess hyporeflective clump speed and size in age-related macular degeneration in the PINNACLE Study. (PINNACLE Study Report 6) Open
Background/Objectives Hyporeflective clumps (HRC) are a common finding in adaptive optics ophthalmoscopy (AOO) of age-related macular degeneration (AMD). They appear on optical coherence tomography (OCT) as hyperreflective foci (HRF) or ab…
View article: IDF diabetes Atlas: A worldwide review of studies utilizing retinal photography to screen for diabetic retinopathy from 2017 to 2024 inclusive
IDF diabetes Atlas: A worldwide review of studies utilizing retinal photography to screen for diabetic retinopathy from 2017 to 2024 inclusive Open
Global DR prevalence remains between 20 and 30%. However, variations in study design and regional practices limit trend interpretation. International screening guidelines, supported by advancing technology, are needed to produce robust epi…
View article: Cryoballoon Pulmonary Vein Isolation in Obese Patients with Atrial Fibrillation Compared to Non-Obese Counterparts: A Meta-Analysis
Cryoballoon Pulmonary Vein Isolation in Obese Patients with Atrial Fibrillation Compared to Non-Obese Counterparts: A Meta-Analysis Open
Introduction: Obesity is an important risk factor for atrial fibrillation (AF) development. Data on cryoballoon ablation (CBA) outcomes in obese patients have so far been scarce. We reviewed the existing literature to compare the efficacy …
View article: The Neutrophil to Lymphocyte Ratio and Other Full Blood Count Indices in Retinal Diseases: A Systematic Review of the Literature
The Neutrophil to Lymphocyte Ratio and Other Full Blood Count Indices in Retinal Diseases: A Systematic Review of the Literature Open
Background and Objectives: The neutrophil to lymphocyte ratio (NLR) and other full blood count indices have been used as a marker of inflammation in a variety of diseases. The aim of the current review is to summarize the existing knowledg…
View article: Factors associated with achieving various visual acuity outcomes during loading doses of aflibercept 2mg for treatment naïve exudative age-related macular degeneration: PRECISE Study Report 7
Factors associated with achieving various visual acuity outcomes during loading doses of aflibercept 2mg for treatment naïve exudative age-related macular degeneration: PRECISE Study Report 7 Open
PURPOSE: To examine baseline OCT characteristics of patients initiated on aflibercept 2mg that achieved good and suboptimal VA after the first injection and post-loading. METHODS: Patients with nAMD initiated on aflibercept therapy were re…
View article: Vitamin D levels in postmenopausal women diagnosed with Central Retinal Vein Occlusion: a case-control study
Vitamin D levels in postmenopausal women diagnosed with Central Retinal Vein Occlusion: a case-control study Open
Purpose To compare Vitamin D levels in postmenopausal women diagnosed with Central Retinal Vein occlusion (CRVO) and investigate if vitamin D deficiency is a risk factor for CRVO in this population. Methods This was a case-control study. P…
View article: Vitreoretinal Interface Abnormalities in Patients With Retinal Vein Occlusion in a Tertiary Referral Center
Vitreoretinal Interface Abnormalities in Patients With Retinal Vein Occlusion in a Tertiary Referral Center Open
The prevalence of VRI disorders in patients with RVO was 16.1% for VMA, 3.2% for VMT, 18.3% for ERM, and 1.1% for LMH. VRI disorders were not found to affect the anatomical and visual outcomes after intravitreal aflibercept treatment in pa…
View article: PON1, APOE and SDF-1 Gene Polymorphisms and Risk of Retinal Vein Occlusion: A Case-Control Study
PON1, APOE and SDF-1 Gene Polymorphisms and Risk of Retinal Vein Occlusion: A Case-Control Study Open
Numerous studies have tried to evaluate the potential role of thrombophilia-related genes in retinal vein occlusion (RVO); however, there is limited research on genes related to different pathophysiological mechanisms involved in RVO. In v…
View article: Subfoveal choroidal thickness changes in patients with pseudoexfoliation syndrome (PEX) compared to healthy controls: A systematic review and meta-analysis
Subfoveal choroidal thickness changes in patients with pseudoexfoliation syndrome (PEX) compared to healthy controls: A systematic review and meta-analysis Open
To investigate changes in choroidal thickness in patients diagnosed with pseudoexfoliation syndrome (PEX) compared to healthy controls, using optical coherence tomography (OCT). PubMed and Scopus databases were systematically searched for …
View article: Risk factors for retinal vein occlusion: Multivariate approach in a case-control study
Risk factors for retinal vein occlusion: Multivariate approach in a case-control study Open
To investigate potential risk factors associated with retinal vein occlusion (RVO) in a Greek population. Case-control study Participants in this study were 106 patients diagnosed with RVO, either central (CRVO) or branch (BRVO), and 76 he…
View article: Optical Coherence Tomography Angiography as a Diagnostic Tool for Diabetic Retinopathy
Optical Coherence Tomography Angiography as a Diagnostic Tool for Diabetic Retinopathy Open
Diabetic retinopathy (DR) is the most common microvascular complication of diabetes mellitus, leading to visual impairment if left untreated. This review discusses the use of optical coherence tomography angiography (OCTA) as a diagnostic …
View article: Optical Coherence Tomography Angiography Changes in Macular Area in Patients with Proliferative Diabetic Retinopathy Treated with Panretinal Photocoagulation
Optical Coherence Tomography Angiography Changes in Macular Area in Patients with Proliferative Diabetic Retinopathy Treated with Panretinal Photocoagulation Open
Background: The purpose of this study was to investigate the changes in macular microvasculature using optical coherence tomography angiography (OCTA) in association with functional changes in patients with proliferative diabetic retinopat…
View article: Vision-Related Quality of Life in Patients With Rhegmatogenous Retinal Detachment Treated With Pars-Plana Vitrectomy: Impact of Gas Tamponade
Vision-Related Quality of Life in Patients With Rhegmatogenous Retinal Detachment Treated With Pars-Plana Vitrectomy: Impact of Gas Tamponade Open
Specific VFQ-25 subscales were decreased in patients with RRD treated with C3F8 as a gas tamponade compared to SF6. This finding warrants further research in the tamponade agents used in PPV surgeries.
View article: Left atrial appendage morphofunctional indices could be predictive of arrhythmia recurrence post-atrial fibrillation ablation: a meta-analysis
Left atrial appendage morphofunctional indices could be predictive of arrhythmia recurrence post-atrial fibrillation ablation: a meta-analysis Open
Background Left atrium changes are implicated in atrial fibrillation (AF) substrate and are predictive of AF outcomes. Left atrial appendage (LAA) is an integral component of left atrial structure and could be affected by atrial cardiomyop…
View article: Retinal microvascular changes in patients recovered from COVID-19 compared to healthy controls: A meta-analysis
Retinal microvascular changes in patients recovered from COVID-19 compared to healthy controls: A meta-analysis Open
View article: Correlation Between Imaging Morphological Findings and Laboratory Biomarkers in Patients with Retinal Vein Occlusion
Correlation Between Imaging Morphological Findings and Laboratory Biomarkers in Patients with Retinal Vein Occlusion Open
View article: Hot balloon versus cryoballoon ablation in patients with atrial fibrillation: a systematic review and meta-analysis
Hot balloon versus cryoballoon ablation in patients with atrial fibrillation: a systematic review and meta-analysis Open
Funding Acknowledgements Type of funding sources: None. Background Atrial fibrillation (AF) incidence is expected to increase more than 60% in the following 30 years. Catheter ablation is the treatment of choice for medically intractable A…
View article: Complete Blood Count-Derived Inflammation Indices and Retinal Vein Occlusion: A Case–Control Study
Complete Blood Count-Derived Inflammation Indices and Retinal Vein Occlusion: A Case–Control Study Open
View article: Inflammatory Biomarkers in Coronary Artery Ectasia: A Systematic Review and Meta-Analysis
Inflammatory Biomarkers in Coronary Artery Ectasia: A Systematic Review and Meta-Analysis Open
Isolated coronary artery ectasia (CAE) is a relatively rare clinical entity, the pathogenesis of which is poorly understood. More and more evidence is accumulating to suggest a critical inflammatory component. We aimed to elucidate any ass…
View article: Choroidal thickness in patients with systemic arterial hypertension: a systematic review and meta-analysis
Choroidal thickness in patients with systemic arterial hypertension: a systematic review and meta-analysis Open
Background: The global burden of hypertension is constantly increasing with adverse cardiovascular and ocular sequelae. The association between elevated blood pressure and choroidal thickness (CT), as assessed via optical coherence tomogra…
View article: Optical coherence angiography changes in macular area in patients with proliferative diabetic retinopathy treated with panretinal photocoagulation: Preliminary results of a prospective study
Optical coherence angiography changes in macular area in patients with proliferative diabetic retinopathy treated with panretinal photocoagulation: Preliminary results of a prospective study Open
View article: Effect of COVID-19-Associated Lockdown on Patients With Diabetic Retinopathy
Effect of COVID-19-Associated Lockdown on Patients With Diabetic Retinopathy Open
Purpose To evaluate the effect of the coronavirus disease 2019 (COVID-19)-related lockdown in the management of patients with diabetic retinopathy (DR), including diabetic macular edema (DME), in a tertiary reference center in Greece.
View article: Predictive Factors for Long-Term Postoperative Visual Outcome in Patients with Macula-Off Rhegmatogenous Retinal Detachment Treated with Vitrectomy
Predictive Factors for Long-Term Postoperative Visual Outcome in Patients with Macula-Off Rhegmatogenous Retinal Detachment Treated with Vitrectomy Open
Purpose: The purpose of this prospective study was to evaluate potential predictive factors of long-term postoperative outcomes in patients with macula-off rhegmatogenous retinal detachment (RRD) treated with pars plana vitrectomy (PPV). M…
View article: Retinal Layers Changes in Patients with Diabetic Macular Edema Treated with Intravitreal Anti-VEGF Agents: Long-Term Outcomes of a Spectral-Domain OCT Study
Retinal Layers Changes in Patients with Diabetic Macular Edema Treated with Intravitreal Anti-VEGF Agents: Long-Term Outcomes of a Spectral-Domain OCT Study Open
Purpose: The purpose of this study was to investigate retinal layers’ changes in patients with diabetic macular edema (DME) treated with anti-vascular endothelial growth factor (anti-VEGF) agents and to evaluate if these chan…