Dimitrios Varrias
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View article: ID: 4349881 ADHERENCE WITH CPAP FOR PATIENTS WITH ATRIAL FIBRILLATION UNDERGOING CATHETER ABLATION: A “REAL-WORLD” ANALYSIS
ID: 4349881 ADHERENCE WITH CPAP FOR PATIENTS WITH ATRIAL FIBRILLATION UNDERGOING CATHETER ABLATION: A “REAL-WORLD” ANALYSIS Open
View article: The Impact of Diagnostic Code and Inclusion Period on Clinical Outcomes in ATTR Cardiomyopathy
The Impact of Diagnostic Code and Inclusion Period on Clinical Outcomes in ATTR Cardiomyopathy Open
View article: GLP-1 RA Use and Major Adverse Cardiovascular Events in Patients With Monoclonal Gammopathy of Undetermined Significance
GLP-1 RA Use and Major Adverse Cardiovascular Events in Patients With Monoclonal Gammopathy of Undetermined Significance Open
Importance Monoclonal gammopathy of undetermined significance (MGUS) is associated with an increased risk of cardiovascular disease. Glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) have demonstrated cardiorenal benefits in patients…
View article: Catheter-Based Therapies in Acute Pulmonary Embolism—Mortality and Safety Outcomes: A Systematic Review and Meta-Analysis
Catheter-Based Therapies in Acute Pulmonary Embolism—Mortality and Safety Outcomes: A Systematic Review and Meta-Analysis Open
Background/Objectives: Right ventricular (RV) dysfunction and circulatory collapse are considered to play a major role in mortality in patients suffering from pulmonary embolism (PE). Catheter-based therapies (CBTs) have been shown to impr…
View article: Anticoagulants or antiplatelets for secondary prevention of cryptogenic stroke: an updated systematic review and meta-analysis
Anticoagulants or antiplatelets for secondary prevention of cryptogenic stroke: an updated systematic review and meta-analysis Open
Background Patients with cryptogenic stroke or embolic stroke of undetermined source (ESUS) face a high risk of recurrent ischaemic stroke, but the optimal antithrombotic strategy remains unclear. This systematic review and meta-analysis c…
View article: Unraveling Heart Inflammation: Recurrent Myopericarditis Caused by Coxsackie A Virus—A Case Report
Unraveling Heart Inflammation: Recurrent Myopericarditis Caused by Coxsackie A Virus—A Case Report Open
Acute recurrent myopericarditis, characterized by the occurrence of a new myopericarditis event following a symptom‐free interval of 4–6 weeks, is relatively rare lacking definitive guidelines for management. Understanding its prevalence, …
View article: Circulating Extracellular Mitochondria in Cardiometabolic Disease: Harnessing the Potential for Diagnosis, Prognosis, and Treatment
Circulating Extracellular Mitochondria in Cardiometabolic Disease: Harnessing the Potential for Diagnosis, Prognosis, and Treatment Open
Mitochondria are crucial for cellular functioning, serving as both an intracellular energy source and a signaling organelle. Recent evidence also highlights their existence outside of cells, where they participate in cell-to-cell communica…
View article: High Prevalence of Unrecognized Actionable Cardiac Arrhythmias in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease
High Prevalence of Unrecognized Actionable Cardiac Arrhythmias in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease Open
Background Patients with chronic obstructive pulmonary disease (COPD) are at high risk for developing arrhythmias due to hypoxemia, right heart failure, and the use of beta-agonist inhalers. Symptoms related to arrhythmias can often be mas…
View article: Cardiomyocyte-derived circulating extracellular vesicles allow a non-invasive liquid biopsy of myocardium in health and disease
Cardiomyocyte-derived circulating extracellular vesicles allow a non-invasive liquid biopsy of myocardium in health and disease Open
SUMMARY The ability to track disease without tissue biopsy in patients is a major goal in biology and medicine. Here, we identify and characterize cardiomyocyte-derived extracellular vesicles in circulation (EVs; “cardiovesicles”) through …
View article: Incidence and predictors of cardiomyopathy after implantation of leadless pacemakers: A comparative analysis with patients with transvenous systems
Incidence and predictors of cardiomyopathy after implantation of leadless pacemakers: A comparative analysis with patients with transvenous systems Open
View article: Circulating Extracellular Mitochondria in Cardiometabolic Disease: Harnessing the Potential for Diagnosis, Prognosis, and Treatment
Circulating Extracellular Mitochondria in Cardiometabolic Disease: Harnessing the Potential for Diagnosis, Prognosis, and Treatment Open
Mitochondria play a significant role in the functioning of the cell, acting both as an intracellular energy source and a signaling organelle. In the heart, mitochondria produce more than 95% of the ATP in addition to regulating the redox s…
View article: Atrial Fibrillation and Dementia: Pathophysiological Mechanisms and Clinical Implications
Atrial Fibrillation and Dementia: Pathophysiological Mechanisms and Clinical Implications Open
Numerous longitudinal studies suggest a strong association between cardiovascular risk factors and cognitive impairment. Individuals with atrial fibrillation are at higher risk of dementia and cognitive dysfunction, as atrial fibrillation …
View article: MicroRNAs are associated with cardiac biomarkers, cardiac structure and function and incident outcomes in heart failure
MicroRNAs are associated with cardiac biomarkers, cardiac structure and function and incident outcomes in heart failure Open
Aims The association between microRNAs (miRNAs) and established cardiac biomarkers is largely unknown. We aimed to measure the association between plasma miRNAs and N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP), cardiac troponin I,…
View article: Differences between Lower Extremity Arterial Occlusion vs. Stenosis and Predictors of Successful Endovascular Interventions
Differences between Lower Extremity Arterial Occlusion vs. Stenosis and Predictors of Successful Endovascular Interventions Open
Background and Objectives: In patients with peripheral artery disease, there is insufficient understanding of characteristics that predict successful revascularization of the lower extremity (LE) chronic total occlusions (CTOs) and baselin…
View article: Comparison of in-hospital outcomes and complications of leadless pacemaker and traditional transvenous pacemaker implantation
Comparison of in-hospital outcomes and complications of leadless pacemaker and traditional transvenous pacemaker implantation Open
Aims Since their introduction in 1958, traditional cardiac pacemakers have undergone considerable upgrades over the years, but they continue to have a complication rate of ∼3.8%–12.4%. There are no randomized controlled trials comparing ou…
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Contents Open
View article: A Case of Type V Hyperlipoproteinemia Resistant to Insulin Treatment
A Case of Type V Hyperlipoproteinemia Resistant to Insulin Treatment Open
View article: Venous Thromboembolism in Pregnancy: Challenges and Solutions
Venous Thromboembolism in Pregnancy: Challenges and Solutions Open
Venous thromboembolism (VTE) is a serious medical condition that can lead to severe morbidity and mortality, making it a significant public health concern. VTE is a multifactorial condition that results from the interaction of genetic, acq…
View article: HIPK1: a New Druggable Kinase Target for Treating Pathological Cardiac Hypertrophy
HIPK1: a New Druggable Kinase Target for Treating Pathological Cardiac Hypertrophy Open
View article: Obesity and Peripheral Artery Disease: Current Evidence and Controversies
Obesity and Peripheral Artery Disease: Current Evidence and Controversies Open
Few reviews and meta-analyses examining systematically the relationship between obesity and PAD exist. The impact of PAD development due to the presence of obesity remains largely controversial. However, the most current evidence, backed b…
View article: Catheter ablation of left atrial tachyarrhythmia: predictors of recurrence after catheter ablation
Catheter ablation of left atrial tachyarrhythmia: predictors of recurrence after catheter ablation Open
Funding Acknowledgements Type of funding sources: None. Background Differently from catheter ablation (CA) of atrial fibrillation (AF), outcome data on CA of atrial re-entrant arrhythmias are scarce. Purpose We sought to evaluate predictor…
View article: Assessment of the Utilization of Validated Diagnostic Predictive Tools and D-Dimer in the Evaluation of Pulmonary Embolism: A Single-Center Retrospective Cohort Study from a Public Hospital in New York City
Assessment of the Utilization of Validated Diagnostic Predictive Tools and D-Dimer in the Evaluation of Pulmonary Embolism: A Single-Center Retrospective Cohort Study from a Public Hospital in New York City Open
Introduction: A significant increase in the use of computed tomography with pulmonary angiography (CTPA) for the diagnosis of pulmonary embolism (PE) has been observed in the past twenty years. We aimed to investigate whether the validated…
View article: Expanding the horizon of EV-RNAs: LncRNAs in EVs as biomarkers for disease pathways
Expanding the horizon of EV-RNAs: LncRNAs in EVs as biomarkers for disease pathways Open
Extracellular vesicles (EVs) are membrane-bound nanoparticles with different types of cargo released by cells and postulated to mediate functions such as intercellular communications. Recent studies have shown that long non-coding RNAs (ln…
View article: PO-03-133 BOTH OVERUSE AND UNDERUSE OF ORAL ANTICOAGULATION POST-ATRIAL FIBRILLATION ABLATION IN A LARGE HEALTHCARE SYSTEM
PO-03-133 BOTH OVERUSE AND UNDERUSE OF ORAL ANTICOAGULATION POST-ATRIAL FIBRILLATION ABLATION IN A LARGE HEALTHCARE SYSTEM Open
View article: Invasive Mechanical Ventilation and Death Was More Likely in Patients with Lower LDL Cholesterol Levels during COVID-19 Hospitalization: A Retrospective Propensity-Matched Cohort Study
Invasive Mechanical Ventilation and Death Was More Likely in Patients with Lower LDL Cholesterol Levels during COVID-19 Hospitalization: A Retrospective Propensity-Matched Cohort Study Open
Hyperlipidemia has been associated with worse outcomes in patients with Coronavirus disease 2019 (COVID-19). However, lower LDL-C (low-density lipoprotein cholesterol) levels have been associated with increased COVID-19 severity and mortal…
View article: 1:1 Tachycardia initiated by a premature ventricular contraction: The curious appeal of the peel
1:1 Tachycardia initiated by a premature ventricular contraction: The curious appeal of the peel Open
View article: REMOTE MONITORING IN PATIENTS WITH CARDIAC IMPLANTABLE ELECTRONIC DEVICES (CIEDS) DURING THE COVID-19 PANDEMIC IN AN URBAN SETTING: SOCIOECONOMIC IMPLICATIONS
REMOTE MONITORING IN PATIENTS WITH CARDIAC IMPLANTABLE ELECTRONIC DEVICES (CIEDS) DURING THE COVID-19 PANDEMIC IN AN URBAN SETTING: SOCIOECONOMIC IMPLICATIONS Open
View article: HOSPITAL VISITS OF PATIENTS ON CARDIAC IMPLANTABLE ELECTRONIC DEVICES (CIEDS) REMOTE MONITORING DURING THE COVID-19 PANDEMIC: SOCIOECONOMIC IMPLICATIONS
HOSPITAL VISITS OF PATIENTS ON CARDIAC IMPLANTABLE ELECTRONIC DEVICES (CIEDS) REMOTE MONITORING DURING THE COVID-19 PANDEMIC: SOCIOECONOMIC IMPLICATIONS Open
View article: HEALTH DISPARITIES IN THE DOOR TO ELECTROCARDIOGRAM TIME IN PATIENTS PRESENTING WITH CHEST PAIN TO THE EMERGENCY DEPARTMENT: INSIGHT FROM ONE OF THE LARGEST PUBLIC CITY HOSPITALS IN THE UNITED STATES
HEALTH DISPARITIES IN THE DOOR TO ELECTROCARDIOGRAM TIME IN PATIENTS PRESENTING WITH CHEST PAIN TO THE EMERGENCY DEPARTMENT: INSIGHT FROM ONE OF THE LARGEST PUBLIC CITY HOSPITALS IN THE UNITED STATES Open
View article: Plasma extracellular vesicle transcriptome as a dynamic liquid biopsy in acute heart failure
Plasma extracellular vesicle transcriptome as a dynamic liquid biopsy in acute heart failure Open
Background Acute decompensation is associated with increased mortality in heart failure (HF) patients, though the underlying etiology remains unclear. Extracellular vesicles (EVs) and their cargo may mark specific cardiovascular physiologi…