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View article: A Diagnosis that Is Probably Missed: Rubeola Lymphadenitis, an Epidemic that Causes a Renewed Alarm
A Diagnosis that Is Probably Missed: Rubeola Lymphadenitis, an Epidemic that Causes a Renewed Alarm Open
Because Rubeola (measles) infection is not observed in our country after eradication and is especially on the agenda again after migrations, pathologists may find it challenging to histopathologically recognize cases of Rubeola lymphadenit…
View article: The Effect of Tumor Budding on Lymph Node Metastasis in Oral Cavity Cancers
The Effect of Tumor Budding on Lymph Node Metastasis in Oral Cavity Cancers Open
Objectives: Oral cavity cancers are the 6 th most common cancer in the world and it is the 20 th among cancer-related deaths and 16 th among women.Tumor budding, which is a prognostic parameter that can be detected histopathologically and …
View article: Concordance of HER2 status tested by IHC and FISH in biopsy and surgical resection specimens and comparison with clinicopathological features in gastric carcinoma
Concordance of HER2 status tested by IHC and FISH in biopsy and surgical resection specimens and comparison with clinicopathological features in gastric carcinoma Open
Context: HER2-targeted therapy has been shown to benefit HER2-positive gastric cancer. It is very important to determine the HER2 expression level correctly to select the appropriate test and sampling method. Aim: In this study, we investi…
View article: Expression of p16 in pterygium and its relation with epithelial dysplasia and possible etiologic role of HPV
Expression of p16 in pterygium and its relation with epithelial dysplasia and possible etiologic role of HPV Open
Context: p16 is an important tumor suppressor gene and responsible for regulating the cell cycle. Diffuse positivity with p16 in the cervix and head/neck carcinomas can be regarded as a surrogate marker of the presence of high-risk human p…
View article: FOXA1 is associated with high tumor grade, myometrial invasion and lymph node invasion in endometrial endometrioid carcinoma
FOXA1 is associated with high tumor grade, myometrial invasion and lymph node invasion in endometrial endometrioid carcinoma Open
FOXA1 expression is higher in endometrial endometrioid carcinoma compared to benign endometrial hyperplasia or intraepithelial neoplasia. In patients with endometrial endometrioid carcinoma, high FOXA1 expression is associated with high tu…
View article: The role of cyclin D1, BCL-2, p53 and Ki-67 in epithelial cells in the etiopathogenesis of pterygium
The role of cyclin D1, BCL-2, p53 and Ki-67 in epithelial cells in the etiopathogenesis of pterygium Open
Context: Pterygium is a degenerative disease that consists of conjunctival epithelia and fibrovascular tissue. Some studies suggest that there is a defect in the regulation of apoptosis in the epithelial cell cycle characterized by the dev…
View article: The diagnostic significance of trophoblast cell-surface antigen-2 expression in benign and malignant thyroid lesions
The diagnostic significance of trophoblast cell-surface antigen-2 expression in benign and malignant thyroid lesions Open
TROP-2 can be considered a useful marker for distinguishing PTC fv cases from follicular nodular disease and follicular adenoma cases because of its high sensitivity in the identification of papillary carcinomas of the thyroid.
View article: Primary cutaneous adenoid cystic carcinoma of the eyelid and literature review
Primary cutaneous adenoid cystic carcinoma of the eyelid and literature review Open
Primary cutaneous adenoid cystic carcinoma (PCACC) is a rare malignant epithelial tumor most commonly observed in the scalp and skin of the chest and originating from the palpebral portion of the lacrimal gland in the orbit. Here we descri…
View article: An extremely rare neoplasm, histiocytic sarcoma: A report of two cases with an aggressive clinical course
An extremely rare neoplasm, histiocytic sarcoma: A report of two cases with an aggressive clinical course Open
Histiocytic sarcoma (HS) is an extremely rare malignant neoplasm accounting for less than 1% of all hemato-lymphoid neoplasms. Sixty percent of all cases are metastatic at presentation and the prognosis is poor. Two cases of HS with an agg…
View article: Expression of claudin 1, 4 and 7 in thyroid neoplasms
Expression of claudin 1, 4 and 7 in thyroid neoplasms Open
The distinction of thyroid carcinoma from benign thyroid neoplasm, as well as the subtyping of papillary carcinoma (PC) and follicular carcinoma (FC), may be performed histopathologically in the majority of cases. However, in certain cases…
View article: The Frequency of Primary Sjogren’s Syndrome and Fibromyalgia in Irritable Bowel Syndrome
The Frequency of Primary Sjogren’s Syndrome and Fibromyalgia in Irritable Bowel Syndrome Open
The frequency of Sjogren's Syndrome among patients with IBS is relatively higher than the general population. All IBS patients should be questioned for dryness of the mouth and eyes, and if necessary, should be evaluated for SS.
View article: Primary Sjögren’s syndrome in patients with celiac disease
Primary Sjögren’s syndrome in patients with celiac disease Open
The prevalence of SS in CD is low, so there is no need for serologic screening of all patients with CD for SS.
View article: Serum level and placental expression of resistin in pregnancies complicated by preeclampsia: relationship with disease severity
Serum level and placental expression of resistin in pregnancies complicated by preeclampsia: relationship with disease severity Open
The authors aimed to compare the maternal serum level and placental expression of resistin in pregnancies complicated by preeclampsia and clarify their relationship with disease severity. This cross-sectional study included 50 healthy preg…
View article: Bardet-Biedl syndrome with vulva carcinoma presented with acute renal failure: a case report.
Bardet-Biedl syndrome with vulva carcinoma presented with acute renal failure: a case report. Open
It should be kept in the mind that renal failure may develop due to constitutional urogenital anomalies such as vulva carcinoma. This can be an important cause of morbidity and mortality in patients with Bardet-Biedl syndrome.Hippokratia 2…
View article: Solitary fibrous tumor of the larynx: Literature review and a case presentation
Solitary fibrous tumor of the larynx: Literature review and a case presentation Open
Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, which is traditionally seen as a pleural mass, but can also occur in other locations. Although SFTs are very rare in the head and neck region, they have been reported in the orbi…
View article: Histopathological evaluation of dental follicles of clinically symptomatic and asymptomatic impacted third molars
Histopathological evaluation of dental follicles of clinically symptomatic and asymptomatic impacted third molars Open
A delay in impacted third molar surgery can lead to further pathological changes in dental follicles and can increase severity of the inflammation. Moreover, dimensions of the pericoronal radiolucency may not provide a correct interpretati…