Explanipedia

3D-Printed Multicompartment Tablet with Dual Drug Release Based on Fused Deposition Modeling Open

Kuldeep Vinchurkar, Sheetal Mane, P. K. Gupta, Dinesh Kumar Mishra · 2025

A PHARMACEUTICO - ANALYTICAL INSIGHTS INTO MADANA MODAKA: AN AYURVEDIC APHRODISIAC Open

Dr Arpitha M S, Dinesh Kumar Mishra, Дубовик Е.В. · 2025

A COMPREHENSIVE ANALYSIS OF RATIONAL AND IRRATIONAL FIXED DOSE COMBINATIONS OF ANTIBACTERIAL DRUGS AVAILABLE IN THE INDIAN MARKET Open

Dinesh Kumar Mishra · 2024

Application of Box-Behnken Design in Optimization of Clobetasol-loaded Nanostructured Lipid Carrier for Topical Use Open

Devkant Sharma, Anjali Sharma, Niladry Sekhar Ghosh, Ranjit Singh, Prabhjot Singh , et al. · 2023

The objective of this study was to optimize nanostructured lipid carriers (NLC) for clobetasol propionate using Box-Behnken design (BBD). The formulation was developed by incorporating oleic acid, compritol ATO-888, and tween 80, using the…

Celiac disease: Pathogenesis, disease management and new insights into the herbal-based treatments Open

Pooja Mittal, Disha Arora, Smriti Parashar, Rajat Goyal, Amir Khan , et al. · 2023

Celiac disease (CD) is a gluten intolerance autoimmune disorder which its symptoms involve the gastrointestinal tract and sometimes the other organs. It is one of the most prevalent health problems rising in many populations as statistics …

Xylan-Based Hydrogels: A Polymeric Carrier for Sustained and Targeted Delivery of Drugs Open

Samit Kumar, Amit Kumar, Dinesh Kumar Mishra · 2022

In spite of good advancement for diagnosis and treatment, cancer is the second most common disease after cardiovascular disorders, may be responsible for maximum deaths in the world. Cancer is a leading cause of death worldwide, accounting…

Phytotherapeutic Potential of Natural Herbal Medicines for Management of Psoriasis: Current Status Open

Nupur Maheshwari, Neelesh Maheshwari, Dinesh Kumar Mishra, Anju Goyal · 2022

Pharmacognosy Research,2023,15,1,42-55.DOI:10.5530/097484900261Published:December 2022Type:Review ReportAuthors:Nupur Maheshwari, Neelesh Maheshwari, Dinesh Kumar Mishra, and Anju Goyal Author(s) affiliations:Nupur Maheshwari1, Neelesh Mah…

Features and Facts of a Gastroretentive Drug Delivery System-A Review Open

Kuldeep Vinchurkar, Jitendra Sainy, MASHEER AHMED KHAN, Sheetal Mane, Dinesh Kumar Mishra , et al. · 2022

English oral delivery of drug was the commonly used modality because of patient compliance and ease of administration. After oral administration of any drug, its bioavailability is affected by its residence time in stomach. Recently, gastr…

An Epidemiological Observation of Judicious use of Antibiotics in Dhar District, M.P. (India) Open

Rekha Bisht, Arvind Dabi, Pankaj Dixit, Dinesh Kumar Mishra · 2021

Background: Antibiotic resistance is presently the gigantic challenge to the effective treatment of infections globally. It is a rapidly growing clinical problem and public health threat. Promiscuous use of antibiotics is epidemic in India…

Estimation of real-infection and immunity against SARS-CoV-2 in Indian populations Open

Prajjval Pratap Singh, Rakesh Tamang, Manoj K. Shukla, Abhishek Pathak, Anshika Srivastava , et al. · 2021

Infection born by Coronavirus SARS-CoV-2 has swept the world within a time of a few months. It has created a devastating effect on humanity with social and economic depressions. Europe and America were the hardest hit continents. India has…

Media Optimization for Production of Recombinant Carrier Protein (CRM197) in Escherichia coli Open

Sudeep Shukla, Dinesh Kumar Mishra · 2021

Since the advent of vaccines, the mankind has benefited from the same and has been able to curb the mortality rate around the globe. Amongst different types of available vaccines, polysaccharide based vaccines are very widely used against …

Rich water, poor people: Potential for transboundary flood management between Nepal and India Open

Nishikant Gupta, Santosh Dahal, Anil Kumar, Chandan Kumar, Mukul Kumar , et al. · 2021

There has been an increase in the frequency and intensity of floods in the region straddling Nepal and northern Bihar. Stricken by acute poverty despite being rich in water resources, frequent floods, and shared vulnerabilities across bord…

Budget impact of capmatinib for adults with metastatic non-small cell lung cancer harboring a MET exon 14 skipping mutation in the United States Open

Beilei Cai, Zheng‐Yi Zhou, Weiguang Xue, Nisha C. Hazra, Mukesh Kumar Singh , et al. · 2021

The estimated budget impact of including capmatinib for mNSCLC with a METex14 skipping mutation is minimal, and the increased drug costs were partially offset by savings in AEs, and progression-related and terminal care costs.

Budget Impact of Dabrafenib and Trametinib in Combination as Adjuvant Treatment of BRAF V600E/K Mutation-Positive Melanoma from a U.S. Commercial Payer Perspective Open

Daniel Stellato, Margaret E. Gerbasi, Briana Ndife, Sameer R. Ghate, Aaron Moynahan , et al. · 2019

Funding for this research was provided to Policy Analysis Inc. (PAI) by Novartis Pharmaceuticals. Stellato, Moynahan, and Delea are employed by PAI. Ndife, Koruth, Mishra, and Gunda are employed by Novartis. Ghate was employed by Novartis …

Gastroretentive Mucoadhesive Microsphere for the Management of Gastric Infection Open

Sri Prakash Mishra, Amit Kumar Nayak, Dinesh Kumar Mishra, Abhay Kumar · 2019

Gastric infections are mostly triggered by Helicobacter pylori (H. pylori), a fungus that colonizes the stomach mucosa of more than 50% of the inhabitants of the world. Chronic H. Pylori diseasewas associated with stomach diseases such as …

Cost-effectiveness of dabrafenib and trametinib in combination as adjuvant treatment of BRAF V600E/K mutation-positive melanoma from a US healthcare payer perspective Open

Margaret E. Gerbasi, Daniel Stellato, Sameer R. Ghate, Briana Ndife, Aaron Moynahan , et al. · 2019

Objective: The COMBI-AD trial demonstrated the efficacy and safety of dabrafenib and trametinib in combination vs placebo as adjuvant treatment of patients with BRAF V600E/K mutation-positive resected Stage IIIA (lymph node metastas…

Dendritic cell engineering for selective targeting of female reproductive tract cancers Open

Arpit Bhargava, Rupesh K. Srivastava, Dinesh Kumar Mishra, Rajnarayan Tiwari, Radhey Shyam Sharma , et al. · 2018

Female reproductive tract cancers (FRCs) are considered as one of the most frequently occurring malignancies and a foremost cause of death among women. The late-stage diagnosis and limited clinical effectiveness of currently available main…

Highly Fluorescent Au25-xAgx Nanoclusters Protected with Poly(ethylene glycol) - and Zwitterion-Modified Thiolate Ligands Open

Dinesh Kumar Mishra, Sisi Wang, Zhicheng Jin, Eric Lochner, Hedi Mattoussi · 2018

We describe the growth and characterization of highly fluorescing, near-infrared-emitting nanoclusters made of bimetallic Au_25-xAg_x cores, prepared using various monothiol-appended hydrophobic and hydrophilic ligands.…

Cost-Effectiveness of Ribociclib plus Letrozole Versus Palbociclib plus Letrozole and Letrozole Monotherapy in the First-Line Treatment of Postmenopausal Women with HR+/HER2- Advanced or Metastatic Breast Cancer: A U.S. Payer Perspective Open

Rohit Mistry, J. May, Gaurav Suri, Kate Young, Diana Brixner , et al. · 2018

Funding for this study was provided by Novartis, which manufactures ribociclib and provided input on the study design and data collection, analysis, and interpretation. Mistry, May, Suri, and Young are employees of PAREXEL. Tang, Mishra, D…

Comparative Hylauronidase enzyme activity of Ayurvedic formulation Triphala guggulu Open

Alok Sharma, Dinesh Kumar Mishra, Karunakar Shukla · 2018

A herbal formulation Triphala Guggulu was prepared based on the method described in Ayurvedic Formulary of India. It contains This triphala guggulu includes Amla (Emblica officinalis), Bibhitaki (Terminalia Bellerica), Haritaki (Terminalia…

Budget Impact of Ribociclib Plus Letrozole For The Treatment of Post-Menopausal Women With Hormone Receptor-Positive (HR+), Human Epidermal Growth Factor Receptor 2- Negative (HER2-) Advanced or Metastatic Breast Cancer From A US Private Third-Party Payer Perspective Open

Rohit Mistry, Gaurav Suri, KC Young, Robert Hettle, JR May , et al. · 2017

Hazards Of Heavy Metals In Contaminated Soils And Food Crops Irrigated With Wastewater In Satna Region Open

Dinesh Kumar Mishra, Manoj shrma, Archna agrawal · 2017

Consumption of food crops contaminated with heavy metals is a major food chain route for human exposure. The main threats to human health from heavy metals are associated with exposure to lead, cadmium, mercury and arsenic. These metals ha…

Designing of Fast Disintegrating Tablets for Antihypertensive Agent Using Superdisintegrants Open

Shivangi Shukla, Dinesh Kumar Mishra, Dinesh Jain · 2016

The aim of present study was to formulate and evaluate Fast dissolving tablet (FDT) of Enalapril maleate. FDT of this drug improved efficacy by minimizing the disintegration time and by providing fast release. FDT of Enalapril maleate, usi…

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