Dingdong Zhang
YOU?
Author Swipe
View article: Molecular Cloning and Expression Profiling of a Bax-Homologous Gene (EsBax) in the Chinese Mitten Crab (Eriocheir sinensis) Under Exogenous Stimulations
Molecular Cloning and Expression Profiling of a Bax-Homologous Gene (EsBax) in the Chinese Mitten Crab (Eriocheir sinensis) Under Exogenous Stimulations Open
EsBax (bcl-2 Associated X protein), a member of the bcl-2 family involved in the mitochondrial apoptosis pathway, plays a crucial role in immune response and defense in invertebrates. In this study, we successfully cloned the full-length c…
View article: ZnO Quantum Dots@CsPbBr <sub>3</sub> Poly‐Heterocrystalline Film Enables High‐Performance Floating‐Gate Transistor Arrays for Edge Computing
ZnO Quantum Dots@CsPbBr <sub>3</sub> Poly‐Heterocrystalline Film Enables High‐Performance Floating‐Gate Transistor Arrays for Edge Computing Open
Nonvolatile optoelectronic synapses motivated by the human eye can effectively function as convolutional kernels to preprocess images, demonstrating significant promise for edge computing. Among the optoelectronic synapses, the floating‐ga…
View article: Benfotiamine, a Lipid‐Soluble Derivative of Vitamin B<sub>1</sub>, Ameliorates the Carbohydrate Overload‐Induced Mitochondrial Dysfunction in Fish <i>Megalobrama amblycephala</i> by Triggering the ULK1‐Mediated Mitophagy
Benfotiamine, a Lipid‐Soluble Derivative of Vitamin B<sub>1</sub>, Ameliorates the Carbohydrate Overload‐Induced Mitochondrial Dysfunction in Fish <i>Megalobrama amblycephala</i> by Triggering the ULK1‐Mediated Mitophagy Open
Compared with mammals, fish have a limited capability to utilize carbohydrates, thus generally suffering from metabolic disorders when offered carbohydrate‐enriched diets. As a synthetic liposoluble derivative of vitamin B 1 , benfotiamine…
View article: Polyimide passivation‐enabled high‐work function graphene transparent electrode for organic light‐emitting diodes with enhanced reliability
Polyimide passivation‐enabled high‐work function graphene transparent electrode for organic light‐emitting diodes with enhanced reliability Open
Chemical vapor deposition (CVD)‐gown graphene has tremendous potential as a transparent electrode for the next generation of flexible optoelectronics such as organic light‐emitting diodes (OLEDs). A semiconductor coating is critical to imp…
View article: Molecular mechanisms underlying sexual precocity in Chinese mitten crab (Eriocheir sinensis): aldh1a1 regulates retinol metabolism via miRNAs in the hepatopancreas
Molecular mechanisms underlying sexual precocity in Chinese mitten crab (Eriocheir sinensis): aldh1a1 regulates retinol metabolism via miRNAs in the hepatopancreas Open
Precocial Eriocheir sinensis, showing advanced sexual maturity, are a serious impediment to crab industry. The aim of this study was to identify miRNAs and its related pathways involved in regulation of precocity in E. sinensis. High-throu…
View article: Aquafeed fermentation improves dietary nutritional quality and benefits feeding behavior, meat flavor, and intestinal microbiota of Chinese mitten crab (Eriocheir sinensis)
Aquafeed fermentation improves dietary nutritional quality and benefits feeding behavior, meat flavor, and intestinal microbiota of Chinese mitten crab (Eriocheir sinensis) Open
Normally, proper fermentation can be an efficient and widely used method to improve feed quality in animal rearing; however, the studies on crustaceans, especially Eriocheir sinensis, remain limited. This study aimed to investigate whether…
View article: Isothermal pressure driven gas microflows in tapered microchannels with circular cross section: numerical and experimental investigations
Isothermal pressure driven gas microflows in tapered microchannels with circular cross section: numerical and experimental investigations Open
International audience
View article: Hyperaminoacidemia induces pancreatic α cell proliferation via synergism between the mTORC1 and CaSR-Gq signaling pathways
Hyperaminoacidemia induces pancreatic α cell proliferation via synergism between the mTORC1 and CaSR-Gq signaling pathways Open
Glucagon has emerged as a key regulator of extracellular amino acid (AA) homeostasis. Insufficient glucagon signaling results in hyperaminoacidemia, which drives adaptive proliferation of glucagon-producing α cells. Aside from mammalian ta…
View article: Dietary T-2 toxin induces transcriptomic changes in hepatopancreas of Chinese mitten crab (Eriocheir sinensis) via nutrition metabolism and apoptosis-related pathways
Dietary T-2 toxin induces transcriptomic changes in hepatopancreas of Chinese mitten crab (Eriocheir sinensis) via nutrition metabolism and apoptosis-related pathways Open
Long-term feed route exposure to T-2 toxin was proved to elicit growth retarding effects and induction of oxidative stress and apoptosis in Chinese mitten crab (Eriocheir sinensis). However, no study with a holistic perspective has been co…
View article: Dietary 18-carbon fatty acid unsaturation improves the muscle fiber development and meat quality of Megalobrama amblycephala
Dietary 18-carbon fatty acid unsaturation improves the muscle fiber development and meat quality of Megalobrama amblycephala Open
The study aimed to investigate the effects of four fatty acids with the same carbon-chain length and different saturations, stearic acid (SA), oleic acid (OA), linoleic acid (LA), and linolenic acid (LNA), on the growth performance and mus…
View article: The Mechanism of Lipopolysaccharide Escaping the Intestinal Barrier in Megalobrama amblycephala Fed a High-Fat Diet
The Mechanism of Lipopolysaccharide Escaping the Intestinal Barrier in Megalobrama amblycephala Fed a High-Fat Diet Open
With the popularity of western food characterized by excessive fat and sugars, obesity has currently been a public health issue. Low-grade chronic inflammation accompanied by obesity increases the risk of multiple epidemics such as diabete…
View article: Evaluation of dietary linoleic acid on growth as well as hepatopancreatic index, lipid accumulation oxidative stress and inflammation in Chinese mitten crabs (Eriocheir sinensis)
Evaluation of dietary linoleic acid on growth as well as hepatopancreatic index, lipid accumulation oxidative stress and inflammation in Chinese mitten crabs (Eriocheir sinensis) Open
This study aimed to investigate the effect of dietary linoleic acid (LA) on the growth, hepatopancreatic development and health of Eriocheir sinensis. Crabs (initial body weight: 28.53 ± 0.63 g) were fed with five formulated diets containi…
View article: Hyperaminoacidemia induces pancreatic α cell proliferation via synergism between mTORC1 and CaSR-Gq signaling pathways
Hyperaminoacidemia induces pancreatic α cell proliferation via synergism between mTORC1 and CaSR-Gq signaling pathways Open
Glucagon has emerged as the main regulator of extracellular amino acid homeostasis. Insufficient glucagon signaling results in hyperaminoacidemia, which drives adaptive proliferation of glucagon-producing α cells. Aside from mammalian targ…
View article: Corticosterone Can Be an Essential Stress Index in Channel Catfish (Ictalurus punctatus)
Corticosterone Can Be an Essential Stress Index in Channel Catfish (Ictalurus punctatus) Open
Although cortisol is considered the main glucocorticoid involved in regulating stress in fish by elevating the serum glucose, the presence of serum corticosterone and whether its level can be used as an indicator for fish stress activation…
View article: Pushing the conductance and transparency limit of monolayer graphene electrodes for flexible organic light-emitting diodes
Pushing the conductance and transparency limit of monolayer graphene electrodes for flexible organic light-emitting diodes Open
Significance Although graphene shows great promise as a generational flexible transparent electrode (FTE), its development has been severely limited by the intrinsic trade-off between electrical conductance and transparency with the perfor…
View article: Dietary Supplementation With Icariin Affects Estrogen Synthesis, Vitellogenesis, and Oocyte Development in the Chinese Mitten Crab, Eriocheir sinensis
Dietary Supplementation With Icariin Affects Estrogen Synthesis, Vitellogenesis, and Oocyte Development in the Chinese Mitten Crab, Eriocheir sinensis Open
In Eriocheir sinensis aquaculture, crabs feeding on an artificial diet without steroid hormones available in ice-fresh fish or snails show delayed ovarian maturation and late listing. Icariin (ICA), a safe plant-derived monomer compound, c…
View article: Metformin improves the glucose homeostasis of Wuchang bream fed high-carbohydrate diets: a dynamic study
Metformin improves the glucose homeostasis of Wuchang bream fed high-carbohydrate diets: a dynamic study Open
After a 12-week feeding trial, the glucose tolerance test was performed in Megalobrama amblycephala to evaluate the effects of metformin on the metabolic responses of glycolipids. Plasma insulin peaked at 2 h, then decreased to the basal v…
View article: Benfotiamine, a Lipid-Soluble Analog of Vitamin B1, Improves the Mitochondrial Biogenesis and Function in Blunt Snout Bream (Megalobrama amblycephala) Fed High-Carbohydrate Diets by Promoting the AMPK/PGC-1β/NRF-1 Axis
Benfotiamine, a Lipid-Soluble Analog of Vitamin B1, Improves the Mitochondrial Biogenesis and Function in Blunt Snout Bream (Megalobrama amblycephala) Fed High-Carbohydrate Diets by Promoting the AMPK/PGC-1β/NRF-1 Axis Open
This study evaluated the effects of benfotiamine on the growth performance and mitochondrial biogenesis and function in Megalobrama amblycephala fed high-carbohydrate (HC) diets. The fish (45.25 ± 0.34 g) were randomly fed six diets: the c…
View article: Molecular Characterization of the RNA-Binding Protein Quaking-a in Megalobrama amblycephala: Response to High-Carbohydrate Feeding and Glucose/Insulin/Glucagon Treatment
Molecular Characterization of the RNA-Binding Protein Quaking-a in Megalobrama amblycephala: Response to High-Carbohydrate Feeding and Glucose/Insulin/Glucagon Treatment Open
The RNA-binding protein quaking-a (Qkia) was cloned from the liver of blunt snout bream Megalobrama amblycephala through the rapid amplification of cDNA ends method, with its potential role in glucose metabolism investigated. The full-leng…
View article: Effect of Dietary Supplementation of Glycyrrhetinic Acid and Tea Polyphenols on Depuration of 2-methylisoborneol from Blunt Snout Bream, Megalobrama amblycephala
Effect of Dietary Supplementation of Glycyrrhetinic Acid and Tea Polyphenols on Depuration of 2-methylisoborneol from Blunt Snout Bream, Megalobrama amblycephala Open
_Off-flavor is a serious issue in cultured fish. It affects marketability and texture of fish and causes great economic losses in the aquaculture industry. Holding fish in a clean-water environment for some time is an effective method to d…