Dinghe Wang
YOU?
Author Swipe
View article: Construction of a novel TROP2/CD3 bispecific antibody with potent antitumor activity and reduced induction of Th1 cytokines
Construction of a novel TROP2/CD3 bispecific antibody with potent antitumor activity and reduced induction of Th1 cytokines Open
Many cancers, including triple-negative breast cancer, overexpress TROP2 on the surface of tumor cells. TROP2 has become a promising tumor associated antigen for the development of novel antibody-based targeted therapy. Herein, we construc…
View article: Inertia matching of CNC cycloidal gear form grinding machine servo system
Inertia matching of CNC cycloidal gear form grinding machine servo system Open
Reasonable ratio between the load inertia and servo motor inertia plays a decisive role for the dynamic performance and stability of the servo system, as well as the machining accuracy of the whole CNC machine. In order to improve the cont…
View article: A Predominant Role of AtEDEM1 in Catalyzing a Rate-Limiting Demannosylation Step of an Arabidopsis Endoplasmic Reticulum-Associated Degradation Process
A Predominant Role of AtEDEM1 in Catalyzing a Rate-Limiting Demannosylation Step of an Arabidopsis Endoplasmic Reticulum-Associated Degradation Process Open
Endoplasmic reticulum-associated degradation (ERAD) is a key cellular process for degrading misfolded proteins. It was well known that an asparagine (N)-linked glycan containing a free α1,6-mannose residue is a critical ERAD signal created…
View article: Mouth-clicks used by blind expert human echolocators – signal description and model based signal synthesis
Mouth-clicks used by blind expert human echolocators – signal description and model based signal synthesis Open
Echolocation is the ability to use sound-echoes to infer spatial information about the environment. Some blind people have developed extraordinary proficiency in echolocation using mouth-clicks. The first step of human biosonar is the tran…
View article: EBS7 is a plant-specific component of a highly conserved endoplasmic reticulum-associated degradation system in <i>Arabidopsis</i>
EBS7 is a plant-specific component of a highly conserved endoplasmic reticulum-associated degradation system in <i>Arabidopsis</i> Open
Significance Endoplasmic reticulum (ER)-associated degradation (ERAD) is a well-studied cellular process in yeast and mammalian systems. Recent molecular and genetic studies in the reference plant Arabidopsis have revealed that ERAD also i…