Dingye Yu YOU? Author Swipe

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Transcriptome profiling of fast/glycolytic and slow/oxidative muscle fibers in aging and obesity Open

Feng‐Min Zhang, Hao-Fan Wu, Kefan Wang, Dingye Yu, Xian-Zhong Zhang , et al. · 2024

A prognostic nomogram integrating carcinoembryonic antigen levels for predicting overall survival in elderly patients with stage II–III colorectal cancer Open

Haijiao Zhang, Rangrang Wang, Tianyu Yu, Dingye Yu, Changfeng Song , et al. · 2024

We constructed a prediction nomogram for stage II-III elderly CRC patients by combining pre-treatment carcinoembryonic antigen (CEA) levels, which can accurately predict patient survival. This facilitates clinicians to accurately assess pa…

Identification of a novel immune-related transcriptional regulatory network in sarcopenia Open

Xian-Zhong Zhang, Guanglou Zhu, Feng‐Min Zhang, Dingye Yu, Xuyang Jia , et al. · 2023

Background Sarcopenia is highly prevalent in elderly individuals and has a significant adverse effect on their physical health and quality of life, but the mechanisms remain unclear. Studies have indicated that transcription factors (TFs) …

A novel insight into the key gene signature associated with the immune landscape in the progression of sarcopenia Open

Zi-Le Shen, Wen‐Hao Chen, Zhang Liu, Dingye Yu, Weizhe Chen , et al. · 2023

Sarcopenia is an age-related skeletal muscle disorder that causes falls, disability and death in the elderly, but its exact mechanism remains unknown. In this study, we merged three GEO datasets into the expression profiles of 118 samples …

Additional file 9 of Identification of a novel immune-related transcriptional regulatory network in sarcopenia Open

Xian-Zhong Zhang, Guanglou Zhu, Feng‐Min Zhang, Dingye Yu, Xuyang Jia , et al. · 2023

Additional file 9. Results of C-Map database.

Additional file 1 of Identification of a novel immune-related transcriptional regulatory network in sarcopenia Open

Xian-Zhong Zhang, Guanglou Zhu, Feng‐Min Zhang, Dingye Yu, Xuyang Jia , et al. · 2023

Additional file 1. Primers of DETFs and final DEGs.

Additional file 2 of Identification of a novel immune-related transcriptional regulatory network in sarcopenia Open

Xian-Zhong Zhang, Guanglou Zhu, Feng‐Min Zhang, Dingye Yu, Xuyang Jia , et al. · 2023

Additional file 2. Results of DEGs.

Additional file 7 of Identification of a novel immune-related transcriptional regulatory network in sarcopenia Open

Xian-Zhong Zhang, Guanglou Zhu, Feng‐Min Zhang, Dingye Yu, Xuyang Jia , et al. · 2023

Additional file 7. Results of DEIGSs.

Additional file 4 of Identification of a novel immune-related transcriptional regulatory network in sarcopenia Open

Xian-Zhong Zhang, Guanglou Zhu, Feng‐Min Zhang, Dingye Yu, Xuyang Jia , et al. · 2023

Additional file 4. Results of ORA.

Additional file 3 of Identification of a novel immune-related transcriptional regulatory network in sarcopenia Open

Xian-Zhong Zhang, Guanglou Zhu, Feng‐Min Zhang, Dingye Yu, Xuyang Jia , et al. · 2023

Additional file 3. Functional enrichment analysis.

Additional file 8 of Identification of a novel immune-related transcriptional regulatory network in sarcopenia Open

Xian-Zhong Zhang, Guanglou Zhu, Feng‐Min Zhang, Dingye Yu, Xuyang Jia , et al. · 2023

Additional file 8. Results of co-analysis.

Additional file 10 of Identification of a novel immune-related transcriptional regulatory network in sarcopenia Open

Xian-Zhong Zhang, Guanglou Zhu, Feng‐Min Zhang, Dingye Yu, Xuyang Jia , et al. · 2023

Additional file 10. Clinical characterization of patients.

Additional file 5 of Identification of a novel immune-related transcriptional regulatory network in sarcopenia Open

Xian-Zhong Zhang, Guanglou Zhu, Feng‐Min Zhang, Dingye Yu, Xuyang Jia , et al. · 2023

Additional file 5. Results of DEPs.

Additional file 6 of Identification of a novel immune-related transcriptional regulatory network in sarcopenia Open

Xian-Zhong Zhang, Guanglou Zhu, Feng‐Min Zhang, Dingye Yu, Xuyang Jia , et al. · 2023

Additional file 6. Results of ssGSEA.

Clinical impact of sarcopenia for overweight or obese patients with colorectal cancer Open

Weizhe Chen, Feng Lin, Dingye Yu, Feng‐Min Zhang, Zi-Le Shen , et al. · 2022

Background: Sarcopenia, overweight and obesity are all dynamic change of body composition, which may have negative effect on the prognosis for patients with colorectal cancer. The aim of this study was to investigate the predictive role of…

Identification of novel immune related transcriptional regulatory network in sarcopenia Open

Xian-Zhong Zhang, Guanglou Zhu, Feng‐Min Zhang, Dingye Yu, Xuyang Jia , et al. · 2022

Background: Sarcopenia is highly prevalent in elderly and has a significant adverse effect on their physical health and quality of life, but the mechanisms remain unclear. Studies have indicated that transcription factors (TFs) and immune …

Coexistence of GLIM-defined malnutrition and sarcopenia have negative effect on the clinical outcomes in the elderly gastric cancer patients after radical gastrectomy Open

Weizhe Chen, Xian-Zhong Zhang, Feng‐Min Zhang, Dingye Yu, Wen‐Hao Chen , et al. · 2022

Background Malnutrition and sarcopenia are common in elderly gastric cancer patients, which are also interrelated and affect each other. We aimed to determine the characteristics of coexistence of malnutrition and sarcopenia in the elderly…

SFMBT1 facilitates colon cancer cell metastasis and drug resistance combined with HMG20A Open

Ruijun Pan, Dingye Yu, Jiajia Hu, Xiao Yang, Chenxing Wang , et al. · 2022

In colorectal cancer (CRC), the development of reagents that increase sensitivity to chemotherapeutic agents could prevent drug resistance and improve patient survival. Scm-like with four malignant brain tumor domains 1 (SFMBT1) is up-regu…

Ginsenoside Rb1 Prevents Oxidative Stress‐Induced Apoptosis and Mitochondrial Dysfunction in Muscle Stem Cells via NF‐<i>κ</i>B Pathway Open

Wen-Xi Dong, Wen‐Hao Chen, Hongbo Zou, Zi-Le Shen, Dingye Yu , et al. · 2022

Sarcopenia, featured by the progressive loss of skeletal muscle function and mass, is associated with the impaired function of muscle stem cells (MuSCs) caused by increasing oxidative stress in senescent skeletal muscle tissue during aging…

Prevalence of Sarcopenia and Its Effect on Postoperative Complications in Patients with Crohn’s Disease Open

Chen Zhang, Dingye Yu, Liwen Hong, Tianyu Zhang, Hua Liu , et al. · 2021

Background and Aims. Sarcopenia is a prognostic factor of outcomes for various diseases, but reports on sarcopenia in patients with Crohn’s disease (CD) are few. We aim to determine the prevalence of sarcopenia and assess the role of sarco…

Identification of Transcription Factor-Related Gene Signature and Risk Score Model for Colon Adenocarcinoma Open

Jianwei Lin, Zichao Cao, Dingye Yu, Wei Cai · 2021

The prognosis of colon adenocarcinoma (COAD) remains poor. However, the specific and sensitive biomarkers for diagnosis and prognosis of COAD are absent. Transcription factors (TFs) are involved in many biological processes in cells. As th…

Super-Enhancer Induced IL-20RA Promotes Proliferation/Metastasis and Immune Evasion in Colorectal Cancer Open

Dingye Yu, Xiao Yang, Jianwei Lin, Zichao Cao, Chenghao Lu , et al. · 2021

Unveiling key oncogenic events in malignancies is the key to improving the prognosis and therapeutic outcome of malignancies. Lines of evidence have shown that super-enhancers control the expression of genes that determine the cell fate, b…

Prevalence of Sarcopenia and Its Effect on Postoperative Complications in Patients With Crohn’s Disease Open

Chen Zhang, Dingye Yu, Liwen Hong, Tianyu Zhang, Hua Liu , et al. · 2021

Background and Aims: Sarcopenia is a prognostic factor of outcomes for various diseases, but reports on sarcopenia in patients with Crohn’s disease (CD) are few. We aim to determine the prevalence of sarcopenia and assess the role of sarco…

Sarcopenia and Adverse Post-Surgical Outcomes in Geriatric Patients: A Scoping Review Open

Md. Zahid Hossain, Dingye Yu, Bavand Bikdeli, S. Yu · 2021

The current review suggests that low muscle mass is associated with higher mortality and various adverse post-surgical outcomes in the elderly. It remains to be determined if applying the definition of sarcopenia as per the international c…

RUNX1 regulates TGF-β induced migration and EMT in colorectal cancer Open

Chenghao Lu, Zheyu Yang, Dingye Yu, Jianwei Lin, Wei Cai · 2020

Colorectal cancer (CRC) was one of the most malignant tumors worldwide due to its metastasis. Epithelial-to-mesenchymal transition (EMT) plays an important role in CRC migration, and transforming growth factor-β (TGF-β) works as a dominati…

Nomogram for Predicting Central Lymph Node Metastasis in Papillary Thyroid Cancer: A Retrospective Cohort Study of Two Clinical Centers Open

Zheyu Yang, Yu Heng, Jianwei Lin, Chenghao Lu, Dingye Yu , et al. · 2020

A validated nomogram utilizing readily available preoperative variables was developed to predict the probability of central lymph node metastases in patients presenting with PTC. This nomogram may help surgeons make appropriate surgical de…

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