Dion Voerman
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View article: Robust Antigen-Specific T Cell Activation within Injectable 3D Synthetic Nanovaccine Depots
Robust Antigen-Specific T Cell Activation within Injectable 3D Synthetic Nanovaccine Depots Open
Synthetic cancer vaccines may boost anticancer immune responses by co-delivering tumor antigens and adjuvants to dendritic cells (DCs). The accessibility of cancer vaccines to DCs and thereby the delivery efficiency of antigenic material g…
View article: Semiflexible Immunobrushes Induce Enhanced T Cell Activation and Expansion
Semiflexible Immunobrushes Induce Enhanced T Cell Activation and Expansion Open
A variety of bioactive materials developed to expand T cells for adoptive transfer into cancer patients are currently evaluated in the clinic. In most cases, T cell activating biomolecules are attached to rigid surfaces or matrices and for…
View article: Influence of Network Topology on the Viscoelastic Properties of Dynamically Crosslinked Hydrogels
Influence of Network Topology on the Viscoelastic Properties of Dynamically Crosslinked Hydrogels Open
Biological materials combine stress relaxation and self-healing with non-linear stress-strain responses. These characteristic features are a direct result of hierarchical self-assembly, which often results in fiber-like architectures. Even…
View article: Influence of Network Topology on the Viscoelastic Properties of Dynamically Crosslinked Hydrogels
Influence of Network Topology on the Viscoelastic Properties of Dynamically Crosslinked Hydrogels Open
Biological materials combine stress relaxation and self-healing with non-linear stress-strain responses. These characteristic features are a direct result of hierarchical self-assembly, which often results in fiber-like architectures. Even…
View article: Influence of Network Topology on the Viscoelastic Properties of Dynamically Crosslinked Hydrogels
Influence of Network Topology on the Viscoelastic Properties of Dynamically Crosslinked Hydrogels Open
Biological materials combine stress relaxation and self-healing with non-linear stress-strain responses. These characteristic features are a direct result of hierarchical self-assembly, which often results in fiber-like architectures. Even…
View article: Synthetic Semiflexible and Bioactive Brushes
Synthetic Semiflexible and Bioactive Brushes Open
Polymer brushes are extensively used for the preparation of bioactive surfaces. They form a platform to attach functional (bio)molecules and control the physicochemical properties of the surface. These brushes are nearly exclusively prepar…
View article: Injectable Biomimetic Hydrogels as Tools for Efficient T Cell Expansion and Delivery
Injectable Biomimetic Hydrogels as Tools for Efficient T Cell Expansion and Delivery Open
Biomaterial-based scaffolds are promising tools for controlled immunomodulation. They can be applied as three dimensional (3D) culture systems in vitro, whereas in vivo they may be used to dictate cellular localization and exert spatiotemp…
View article: Nonlinear mechanics of hybrid polymer networks that mimic the complex mechanical environment of cells
Nonlinear mechanics of hybrid polymer networks that mimic the complex mechanical environment of cells Open
The mechanical properties of cells and the extracellular environment they reside in are governed by a complex interplay of biopolymers. These biopolymers, which possess a wide range of stiffnesses, self-assemble into fibrous composite netw…
View article: Patterning of Soft Matter across Multiple Length Scales
Patterning of Soft Matter across Multiple Length Scales Open
Controlling the organization of functional supramolecular materials at both short and long length scales as well as creating hierarchical patterns is essential for many biological and electrooptical applications. It remains however an extr…