Dirk Lanzerath
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View article: Fostering Research Integrity through Training: The training materials of four EU-funded projects through the lens of pedagogical underpinnings and three taxonomies of learning
Fostering Research Integrity through Training: The training materials of four EU-funded projects through the lens of pedagogical underpinnings and three taxonomies of learning Open
Background This article provides an analysis of the pedagogical underpinnings that characterise the research integrity (RI) training approaches and materials developed by four European Union - funded projects. The approaches taken by these…
View article: Longitudinal associations of structural and functional brain connectivity with dimensions of psychopathology in adolescence
Longitudinal associations of structural and functional brain connectivity with dimensions of psychopathology in adolescence Open
These findings highlight the dynamic interplay between brain connectivity development and psychopathology in adolescence, with potential implications for identifying neural markers of risk and resilience during sensitive windows of develop…
View article: Personality, Social Factors, Brain Functioning, Familial Risk, and Trajectories of Alcohol Misuse in Adolescence
Personality, Social Factors, Brain Functioning, Familial Risk, and Trajectories of Alcohol Misuse in Adolescence Open
Importance The development of an alcohol use disorder in adolescence is associated with increased risk of future alcohol dependence. The differential associations of risk factors with alcohol use over the course of 8 years are important fo…
View article: Künstliche Intelligenz in der Medizin
Künstliche Intelligenz in der Medizin Open
View article: VIRT<sup>2</sup>UE: A European train-the-trainer programme for teaching research integrity
VIRT<sup>2</sup>UE: A European train-the-trainer programme for teaching research integrity Open
Universities and other research institutions are increasingly providing additional training in research integrity to improve the quality and reliability of research. Various training courses have been developed, with diverse learning goals…
View article: VIRT²UE: A European Train-the-Trainer Programme for Teaching Research Integrity
VIRT²UE: A European Train-the-Trainer Programme for Teaching Research Integrity Open
Universities and other research institutions are increasingly providing additional training in research integrity (RI) in an attempt to improve the quality and reliability of research. Various training courses have been developed, with div…
View article: Die normative Praxis von Gesundheit und Krankheit
Die normative Praxis von Gesundheit und Krankheit Open
TheN ormative Practiceo fH ealth and Disease."Health" and "disease" are frequentlyu sed terms with ah ighr elevance for our everydayl ives.Their spectrum of meaning is very extensive,but also ambivalent,because they are not adequately capt…
View article: SIENNA D6.3: Methods for translating ethical analysis into instruments for the ethical development and deployment of emerging technologies
SIENNA D6.3: Methods for translating ethical analysis into instruments for the ethical development and deployment of emerging technologies Open
In this SIENNA deliverable we present five general methods for translating ethical analysis into frameworks and methods for the ethical guidance of new emerging technologies. These are: a multistakeholder, coevolutionary strategy for ethic…
View article: PRO-Ethics D1.2 Paper Manuscript on Participatory Practices and Ethics Issues in Innovation
PRO-Ethics D1.2 Paper Manuscript on Participatory Practices and Ethics Issues in Innovation Open
Aiming at designing a comprehensive approach to ethics and participation, this study encompasses general features and configurations of ethics in the field of research and innovation, to further connect them with participatory practices br…
View article: Differential predictors for alcohol use in adolescents as a function of familial risk
Differential predictors for alcohol use in adolescents as a function of familial risk Open
View article: PRO-Ethics D1.2 Paper Manuscript on Participatory Practices and Ethics Issues in Innovation
PRO-Ethics D1.2 Paper Manuscript on Participatory Practices and Ethics Issues in Innovation Open
Aiming at designing a comprehensive approach to ethics and participation, this study encompasses general features and configurations of ethics in the field of research and innovation, to further connect them with participatory practices br…
View article: Substance Use Initiation, Particularly Alcohol, in Drug-Naive Adolescents: Possible Predictors and Consequences From a Large Cohort Naturalistic Study
Substance Use Initiation, Particularly Alcohol, in Drug-Naive Adolescents: Possible Predictors and Consequences From a Large Cohort Naturalistic Study Open
These results suggest that the transition from no use to frequent drinking in early to mid-adolescence may disrupt normative developmental changes in behavioral control. In addition, blunted activity of the medial orbitofrontal cortex duri…
View article: Paper Manuscript on Participatory Practices and Ethics Issues in Innovation
Paper Manuscript on Participatory Practices and Ethics Issues in Innovation Open
Aiming at designing a comprehensive approach to ethics and participation, this study encompasses general features and configurations of ethics in the field of research and innovation, to further connect them with participatory practices br…
View article: COVID-19 human challenge trials – what research ethics committees need to consider
COVID-19 human challenge trials – what research ethics committees need to consider Open
To reduce the global burden of the COVID-19 pandemic, there is an urgent need to develop a safe vaccine. Vaccine development usually takes many years as it goes through several different phases. To hasten COVID-19 vaccine development, it h…
View article: The ethics of COVID-19 tracking apps – challenges and voluntariness
The ethics of COVID-19 tracking apps – challenges and voluntariness Open
As COVID-19 continues to spread, a variety of COVID-19 tracking apps (CTAs) have been introduced to help contain the pandemic. Deployment of this technology poses serious challenges of effectiveness, technological problems and risks to pri…
View article: The IMAGEN study: a decade of imaging genetics in adolescents
The IMAGEN study: a decade of imaging genetics in adolescents Open
Imaging genetics offers the possibility of detecting associations between genotype and brain structure as well as function, with effect sizes potentially exceeding correlations between genotype and behavior. However, study results are ofte…
View article: Rotatory role-playing and role-models to enhance the research integrity culture
Rotatory role-playing and role-models to enhance the research integrity culture Open
The Path2Integrity project is a two-component coordination and support action to enhance research integrity cultures. Path2Integrity develops and fosters role-models and rotatory role-play scenarios for secondary school students, undergrad…
View article: SIENNA D4.3: Survey of REC approaches and codes for Artificial Intelligence & Robotics
SIENNA D4.3: Survey of REC approaches and codes for Artificial Intelligence & Robotics Open
This report describes the outcome of task 4.3, Current coverage of ethical guidelines by professional organisations, ethics advisory groups, and research ethics committees for Artificial Intelligence and Robotics (AI&R). For this task, the…
View article: SIENNA D3.3: Survey of REC approaches and codes for human enhancement
SIENNA D3.3: Survey of REC approaches and codes for human enhancement Open
This report describes the outcome of task 3.3, the current coverage of ethical guidelines by professional organisations, ethics advisory groups, and research ethics committees for human enhancement. For this task the SIENNA partners search…
View article: Cannabis-Associated Psychotic-like Experiences Are Mediated by Developmental Changes in the Parahippocampal Gyrus
Cannabis-Associated Psychotic-like Experiences Are Mediated by Developmental Changes in the Parahippocampal Gyrus Open
View article: Attitudes toward the right to autonomous decision‐making in psychiatric genetic testing: Controversial and context‐dependent
Attitudes toward the right to autonomous decision‐making in psychiatric genetic testing: Controversial and context‐dependent Open
Recent breakthroughs in psychiatric genetics have identified genetic risk factors of yet unknown clinical value. A main ethical principal in the context of psychiatric research as well as future clinical genetic testing is the respect for …
View article: Neural Correlates of Failed Inhibitory Control as an Early Marker of Disordered Eating in Adolescents
Neural Correlates of Failed Inhibitory Control as an Early Marker of Disordered Eating in Adolescents Open
Greater recruitment of the medial prefrontal and anterior cingulate regions during failed inhibition accords with abnormal evaluation of errors contributing to DEB development. As this precedes symptom onset and is evident despite normal t…
View article: Advance directives for future dementia can be modified by a brief video presentation on dementia care: An experimental study
Advance directives for future dementia can be modified by a brief video presentation on dementia care: An experimental study Open
Anticipated decisions regarding life-sustaining measures are negatively influenced by the subjective imagination of living with dementia, which might be shaped by common, unquestioned stereotypes. This bias can be reduced by providing audi…
View article: SIENNA D1.1: The consortium's methodological handbook
SIENNA D1.1: The consortium's methodological handbook Open
This Handbook brings together and describes the SIENNA project’s theoretical and methodological approaches for ethical, legal and human rights analyses, societal acceptance and awareness studies, development of research ethics protocols an…
View article: 4. Ethische Kriterien und Argumente im Wandel der Zeit
4. Ethische Kriterien und Argumente im Wandel der Zeit Open
Vierter Gentechnologiebericht , Seite 103 - 128
View article: Fostering responsible research with genome editing technologies: a European perspective
Fostering responsible research with genome editing technologies: a European perspective Open
View article: Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents
Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents Open
View article: Neural basis of reward anticipation and its genetic determinants
Neural basis of reward anticipation and its genetic determinants Open
Significance We characterize in humans a coordinated network of brain activity describing neurobehavioral correlates of reward anticipation. The network involves nodes in striatal and cortical brain regions, which are preferentially associ…
View article: Rsu1 regulates ethanol consumption in <i>Drosophila</i> and humans
Rsu1 regulates ethanol consumption in <i>Drosophila</i> and humans Open
Significance Genetic factors play a major role in the development of human addiction. Identifying these genes and understanding their molecular mechanisms are necessary first steps in the development of targeted therapeutic intervention. H…
View article: Correlated gene expression supports synchronous activity in brain networks
Correlated gene expression supports synchronous activity in brain networks Open
Cooperating brain regions express similar genes When the brain is at rest, a number of distinct areas are functionally connected. They tend to be organized in networks. Richiardi et al. compared brain imaging and gene expression data to bu…