Dirk Rommel
YOU?
Author Swipe
View article: Thermally Assisted Microfluidics to Produce Chemically Equivalent Microgels with Tunable Network Morphologies
Thermally Assisted Microfluidics to Produce Chemically Equivalent Microgels with Tunable Network Morphologies Open
Although micron‐sized microgels have become important building blocks in regenerative materials, offering decisive interactions with living matter, their chemical composition mostly significantly varies when their network morphology is tun…
View article: Thermally Assisted Microfluidics to Produce Chemically Equivalent Microgels with Tunable Network Morphologies
Thermally Assisted Microfluidics to Produce Chemically Equivalent Microgels with Tunable Network Morphologies Open
Although micron‐sized microgels have become important building blocks in regenerative materials, offering decisive interactions with living matter, their chemical composition mostly significantly varies when their network morphology is tun…
Varying the Stiffness and Diffusivity of Rod‐Shaped Microgels Independently through Their Molecular Building Blocks Open
Microgels are water‐swollen, crosslinked polymers that are widely used as colloidal building blocks in scaffold materials for tissue engineering and regenerative medicine. Microgels can be controlled in their stiffness, degree of swelling,…
Varying the Stiffness and Diffusivity of Rod‐Shaped Microgels Independently through Their Molecular Building Blocks Open
Microgels are water‐swollen, crosslinked polymers that are widely used as colloidal building blocks in scaffold materials for tissue engineering and regenerative medicine. Microgels can be controlled in their stiffness, degree of swelling,…
Microgels as Platforms for Antibody‐Mediated Cytokine Scavenging Open
Therapeutic antibodies are the key treatment option for various cytokine‐mediated diseases, such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease. However, systemic injection of these antibodies can cause side effects and…
View article: Nonspherical ultrasound microbubbles
Nonspherical ultrasound microbubbles Open
Surface tension provides microbubbles (MB) with a perfect spherical shape. Here, we demonstrate that MB can be engineered to be nonspherical, endowing them with unique features for biomedical applications. Anisotropic MB were generated via…
Annealing High Aspect Ratio Microgels into Macroporous 3D Scaffolds Allows for Higher Porosities and Effective Cell Migration Open
Growing millimeter‐scaled functional tissue remains a major challenge in the field of tissue engineering. Therefore, microporous annealed particles (MAPs) are emerging as promising porous biomaterials that are formed by assembly of microge…
Functionalized Microgel Rods Interlinked into Soft Macroporous Structures for 3D Cell Culture (Adv. Sci. 10/2022) Open
Rod‐Shaped Microgels A two‐component system consisting of microgel rods creates macroporous interlinked constructs for cell culture in 3D with pores up to several hundreds of micrometers. The functionalized microgel rods that interlink wit…
Functionalized Microgel Rods Interlinked into Soft Macroporous Structures for 3D Cell Culture Open
In this work, a two component microgel assembly using soft anisometric microgels that interlink to create a 3D macroporous construct for cell growth is reported. Reactive microgel rods with variable aspect ratio are produced via microfluid…
Leucomethylene blue probe detects a broad spectrum of reactive oxygen and nitrogen species Open
A broad spectrum ROS/RNS sensing butylated phenol tethered leucomethylene blue is presented. This probe detects a variety of ROS/RNS, with up to 100-fold gain in fluorescence in the red range, is suitable for microscopic and macroscopic in…
Unravelling colloid filter cake motions in membrane cleaning procedures Open
The filtration performance of soft colloid suspensions suffers from the agglomeration of the colloids on the membrane surface as filter cakes. Backflushing of fluid through the membrane and cross-flow flushing across the membrane are widel…
Drug Loading in Poly(butyl cyanoacrylate)-Based Polymeric Microbubbles Open
Microbubbles (MB) are routinely used ultrasound (US) contrast agents that have recently attracted increasing attention as stimuli-responsive drug delivery systems. To better understand MB-based drug delivery, we studied the role of drug hy…
Multimodal and multiscale optical imaging of nanomedicine delivery across the blood-brain barrier upon sonopermeation Open
Rationale: The blood-brain barrier (BBB) is a major obstacle for drug delivery to the brain. Sonopermeation, which relies on the combination of ultrasound and microbubbles, has emerged as a powerful tool to permeate the BBB, enabling the e…
Compartmentalized Jet Polymerization as a High‐Resolution Process to Continuously Produce Anisometric Microgel Rods with Adjustable Size and Stiffness Open
In the past decade, anisometric rod‐shaped microgels have attracted growing interest in the materials‐design and tissue‐engineering communities. Rod‐shaped microgels exhibit outstanding potential as versatile building blocks for 3D hydroge…
Shelf-Life Evaluation and Lyophilization of PBCA-Based Polymeric Microbubbles Open
Poly(n-butyl cyanoacrylate) microbubbles (PBCA-MB) are extensively employed for functional and molecular ultrasound (US) imaging, as well as for US-mediated drug delivery. To facilitate the use of PBCA-MB as a commercial platform for biome…