Divendu Bhushan
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View article: Role of platelet-related parameters in prediction of development and severity of preeclampsia (PE): an observational prospective cohort study
Role of platelet-related parameters in prediction of development and severity of preeclampsia (PE): an observational prospective cohort study Open
Objectives: Preeclampsia (PE) is a major contributor to maternal and foetal morbidity and mortality. Early identification of women at risk is crucial for timely intervention, yet a cost-effective and reliable screening tool remains unavail…
View article: Role of platelet counts to spleen length ratio and platelet-albumin to spleen length ratio as non-invasive predictors of esophageal varices in chronic liver disease patients: A cross-sectional study in Eastern India
Role of platelet counts to spleen length ratio and platelet-albumin to spleen length ratio as non-invasive predictors of esophageal varices in chronic liver disease patients: A cross-sectional study in Eastern India Open
A BSTRACT Objective: This study aimed to evaluate and compare the diagnostic performance of the Platelet/Spleen Length (P/SL) ratio and a novel metric, the Platelet-Albumin/Spleen Length (P*Alb/SL) ratio, in predicting esophageal varices (…
View article: Clinical Profile and Outcomes of Patients with Heat Stroke: An Observational Study from a Tertiary Care Center in Eastern India
Clinical Profile and Outcomes of Patients with Heat Stroke: An Observational Study from a Tertiary Care Center in Eastern India Open
Background: Heat stroke is a growing public health concern exacerbated by rising temperatures and prolonged heat waves. This study examines the clinical profile, prognostic markers, and outcomes of heat stroke patients presenting to a tert…
View article: Atypical Presentations of Hypopituitarism: A Report of Two Cases
Atypical Presentations of Hypopituitarism: A Report of Two Cases Open
Hypopituitarism is a relatively uncommon endocrine disorder with varying prevalence rates among different populations. Growth hormone deficiency is one of the common hormone deficiencies in hypopituitarism, followed by deficiencies in gona…
View article: Occult neuroparalytic snakebite: A diagnostic challenge
Occult neuroparalytic snakebite: A diagnostic challenge Open
View article: A Study on The Proportion/Hospital Based Prevalance of Non-Alcoholic Fatty Liver Disease (NAFLD) in Diagnosed Cases of Polycystic Ovarian Syndrome (PCOS) Seen in A Tertiary Care Centre of Bihar
A Study on The Proportion/Hospital Based Prevalance of Non-Alcoholic Fatty Liver Disease (NAFLD) in Diagnosed Cases of Polycystic Ovarian Syndrome (PCOS) Seen in A Tertiary Care Centre of Bihar Open
1.1. Aims To evaluate the proportion/hospital-based prevalence of non-alcoholic fatty liver disease in diagnosed cases of polycystic ovarian syndrome and to evaluate and compare the various relevant biochemical parameters and their derange…
View article: Prevalence of Device Associated Hospital acquired infection in a Medical Intensive Care Unit of a Tertiary Care Centre
Prevalence of Device Associated Hospital acquired infection in a Medical Intensive Care Unit of a Tertiary Care Centre Open
Background: Infections acquired within a hospital setting, commonly called healthcare-associated infections (HAIs), are nosocomial infections that are typically absent or in an incubation phase upon admission. The study aimed to determine …
View article: A prospective, multicentre study evaluating safety and efficacy of a fixed dose combination of Remogliflozin etabonate, Vildagliptin, and Metformin in Indian patients with type 2 diabetes mellitus (Triad-RMV)
A prospective, multicentre study evaluating safety and efficacy of a fixed dose combination of Remogliflozin etabonate, Vildagliptin, and Metformin in Indian patients with type 2 diabetes mellitus (Triad-RMV) Open
View article: Recounting COVID-19 associated complement-mediated coagulopathies: Triggers and controls
Recounting COVID-19 associated complement-mediated coagulopathies: Triggers and controls Open
The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to a global health crisis, prompting extensive research into its pathogenesis and potential therapeutic interve…
View article: Neutrophil-to-Lymphocyte Ratio as a Prognostic Marker of Functional Outcome in Patients With Intracerebral Hemorrhage (ICH) and Its Comparison With ICH Score: A Hospital-Based Study
Neutrophil-to-Lymphocyte Ratio as a Prognostic Marker of Functional Outcome in Patients With Intracerebral Hemorrhage (ICH) and Its Comparison With ICH Score: A Hospital-Based Study Open
NLR is a potential prognostic marker for ICH outcomes, showing significant predictive value at 90 days follow-up. However, the ICH score remains a more reliable predictor. Integrating NLR into the ICH score may enhance its prognostic accur…
View article: Prevalence of SARS-CoV-2 virus in saliva, stool, and urine samples of COVID-19 patients in Bihar, India
Prevalence of SARS-CoV-2 virus in saliva, stool, and urine samples of COVID-19 patients in Bihar, India Open
Introduction. The coronavirus illness caused by SARS-CoV-2 can cause multiple organ involvement, with varying degrees of severity. Besides inhalation as a route for transmission, feco-oral has also been proposed. Its transmission to sewage…
View article: Healthcare-associated Infection Surveillance in Low- and Middle-income Countries: Challenges, Opportunities, and the Way Forward
Healthcare-associated Infection Surveillance in Low- and Middle-income Countries: Challenges, Opportunities, and the Way Forward Open
The search strategy included a combination of medical subject headings (MeSH) and keywords related to HAIs, surveillance, and epidemiology.They are as follows.
View article: Hepatic Hydrothorax in the Background of Minimal or No Ascites: A Case Report
Hepatic Hydrothorax in the Background of Minimal or No Ascites: A Case Report Open
InvestigationsThe examination findings were corroborated by the chest X-ray, which showed the presence of pleural effusion in the right middle and lower zones (Fig. 1).Direct microscopy of the pleural fluid showed 150 cells/mL 3 with a neu…
View article: Title of Manuscript: Prevalence of SARS- CoV-2 virus in saliva, stool, and urine samples of COVID-19 patients in Bihar, India
Title of Manuscript: Prevalence of SARS- CoV-2 virus in saliva, stool, and urine samples of COVID-19 patients in Bihar, India Open
Introduction The coronavirus illness caused by SARS- CoV-2 can cause multiple organ involvement, with varying degrees of severity. Besides, inhalation as a route for transmission, feco-oral has also been proposed. Its transmission to sewag…
View article: The Kaleidoscope of Polyautoimmunity: An Odyssey of Diagnostic Dilemmas
The Kaleidoscope of Polyautoimmunity: An Odyssey of Diagnostic Dilemmas Open
Diagnostic accuracy is of the utmost importance, both in the clinical setting and for research purposes. Mixed connective tissue disease (MCTD), rheumatoid arthritis (RA), Sjogren's syndrome (SS), and overlap syndrome (OS) frequently exhib…
View article: Title of Manuscript: Prevalence of SARS- CoV-2 virus in saliva, stool, and urine samples of COVID-19 patients in Bihar, India
Title of Manuscript: Prevalence of SARS- CoV-2 virus in saliva, stool, and urine samples of COVID-19 patients in Bihar, India Open
Introduction The coronavirus illness caused by SARS- CoV-2 can cause multiple organ involvement, with varying degrees of severity. Besides, inhalation as a route for transmission, feco-oral has also been proposed. Its transmission to sewag…
View article: Title of Manuscript: Prevalence of SARS- CoV-2 virus in saliva, stool, and urine samples of COVID-19 patients in Bihar, India
Title of Manuscript: Prevalence of SARS- CoV-2 virus in saliva, stool, and urine samples of COVID-19 patients in Bihar, India Open
Introduction The coronavirus illness caused by SARS- CoV-2 can cause multiple organ involvement, with varying degrees of severity. Besides, inhalation as a route for transmission, feco-oral has also been proposed. Its transmission to sewag…
View article: Reviewer response for version 1
Reviewer response for version 1 Open
Background: Cryptococcos noeformans is a ubiquitous fungal infection that can cause life threatening meningitis and fungemia in both immunocompromised and immunocompetent host. Disseminated cryptococcosis is often a retrospective diagnosis…
View article: Fatal disseminated Cryptococcosis with diverse risk factors: A Case series from a tertiary care hospital in eastern India
Fatal disseminated Cryptococcosis with diverse risk factors: A Case series from a tertiary care hospital in eastern India Open
Background: Cryptococcos noeformans is a ubiquitous fungal infection that can cause life threatening meningitis and fungemia in both immunocompromised and immunocompetent host. Disseminated cryptococcosis is often a retrospective diagnosis…
View article: The Prevalence of Thyroid Abnormalities in Patients With Chronic Kidney Disease: A Cross-Sectional Study at a Tertiary Care Hospital
The Prevalence of Thyroid Abnormalities in Patients With Chronic Kidney Disease: A Cross-Sectional Study at a Tertiary Care Hospital Open
Background and objective Chronic kidney disease (CKD) is a clinical syndrome characterized by the irreversible loss of kidney function. It is a widespread condition affecting populations worldwide. The kidneys play a crucial role in the me…
View article: Interference of anti-nuclear antibodies on determination of anti-neutrophil cytoplasmic antibodies in patients suspected of vasculitis
Interference of anti-nuclear antibodies on determination of anti-neutrophil cytoplasmic antibodies in patients suspected of vasculitis Open
Anti-neutrophil cytoplasmic antibodies (ANCA) are mainly associated with medium and small vessel vasculitis. Two main methodologies currently available for detection of these antibodies are indirect immunofluorescence (IIF) and monospecifi…
View article: Role of Dantabija, Haridra, and Zingiber (DHZ) combination to restore health and immunity in mild to moderate COVID-19 patients
Role of Dantabija, Haridra, and Zingiber (DHZ) combination to restore health and immunity in mild to moderate COVID-19 patients Open
A BSTRACT Background: COVID-19 (SARS-CoV-2) has caused various clinical manifestations ranging from asymptomatic, minor flu-like symptoms to acute respiratory distress syndrome (ARDS), pneumonia, and even death. Early restriction of viruse…
View article: Efficacy of intravenous vitamin C in management of moderate and severe COVID-19: A double blind randomized placebo controlled trial
Efficacy of intravenous vitamin C in management of moderate and severe COVID-19: A double blind randomized placebo controlled trial Open
Aim: To study the efficacy of intravenous vitamin C in management of moderate and severe COVID-19. Objective: To determine the efficacy of intravenous vitamin C in reducing in-hospital mortality in moderate and severe cases of COVID-19. De…
View article: Role of cystatin C and calprotectin as potential early prognostic biomarkers in COVID-19 patients admitted to a dedicated COVID care facility
Role of cystatin C and calprotectin as potential early prognostic biomarkers in COVID-19 patients admitted to a dedicated COVID care facility Open
Background: The COVID-19 pandemic has claimed millions of lives. A tool for early prediction of severity and mortality risk is desirable for better utilization of health care facilities. Several biomarkers like D-dimer, lactate dehydrogena…
View article: Clinical utility of MRI in acute stroke beyond reperfusion therapy
Clinical utility of MRI in acute stroke beyond reperfusion therapy Open
A BSTRACT Background: Stroke is primarily a clinical diagnosis. It can be hemorrhagic or ischemic in etiology. Computed tomography (CT) brain is usually the initial investigation in most patients with suspected stroke. Although it has exce…
View article: Clinico-pathological profile of pancytopenia patients in a single health care centre of northern India
Clinico-pathological profile of pancytopenia patients in a single health care centre of northern India Open
A BSTRACT Background: Pancytopenia is a clinical outcome of various pathological conditions ranging from bone marrow suppression, bone marrow infiltration, infections, hypersplenism, haemolysis, and haematological malignancies. As such is …
View article: Interim Analysis of Impact of Adding Low Dose Pulmonary Radiotherapy to Moderate COVID-19 Pneumonia Patients: IMpaCt-RT Study
Interim Analysis of Impact of Adding Low Dose Pulmonary Radiotherapy to Moderate COVID-19 Pneumonia Patients: IMpaCt-RT Study Open
Background Treatment for coronavirus disease 2019 (COVID-19) pneumonia remains largely supportive till date and multiple clinical trials took place within the short span of time to evaluate the role of investigational therapies. The anti-i…
View article: Platypnea-orthodeoxia Syndrome: An Important Cause of Morbidity in Post Coronavirus Disease Patients
Platypnea-orthodeoxia Syndrome: An Important Cause of Morbidity in Post Coronavirus Disease Patients Open
Bhushan D, Kumar V, Sahoo BH, Hegde A. Platypnea-orthodeoxia Syndrome: An Important Cause of Morbidity in Post Coronavirus Disease Patients. Indian J Crit Care Med 2022;26(3):401-402.
View article: Hemichorea-hemiballismus as a rare presentation of non-ketotic hyperglycemia: a case report
Hemichorea-hemiballismus as a rare presentation of non-ketotic hyperglycemia: a case report Open
Hemichorea-hemiballismus is a hyperkinetic movement disorder on one side of the body resulting from involvement of the contralateral basal ganglia and striatum mainly. A 50-year-old female presented with a 5-days history of choreiform move…
View article: Determinants of Survival in obstetric Sepsis: Retrospective Observational Study
Determinants of Survival in obstetric Sepsis: Retrospective Observational Study Open