Divya Kamath
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View article: Advances in glyconanotechnology based biomedical applications
Advances in glyconanotechnology based biomedical applications Open
There is an emerging awareness in cancer biology that glycobiology plays a significant, if not decisive role in oncogenesis, tumor survival, and proliferation. The human glycome is even more complex than the human genome, because glycans a…
View article: Anti-apoptotic Proteolysis Targeted Chimeras (PROTACs) in Cancer Therapy
Anti-apoptotic Proteolysis Targeted Chimeras (PROTACs) in Cancer Therapy Open
Targeted protein degradation is an emerging approach for novel drug discovery and basic research. Several degrader molecules have been developed including PROteolysis-TArgeting Chimeras (PROTACs), specific and nongenetic Inhibitor of APopt…
View article: The Loop 2 Region of Ribosomal Protein uS5 Influences Spectinomycin Sensitivity, Translational Fidelity, and Ribosome Biogenesis
The Loop 2 Region of Ribosomal Protein uS5 Influences Spectinomycin Sensitivity, Translational Fidelity, and Ribosome Biogenesis Open
Ribosomal protein uS5 is an essential component of the small ribosomal subunit that is involved in subunit assembly, maintenance of translational fidelity, and the ribosome's response to the antibiotic spectinomycin. While many of the char…
View article: An investigation into the effects of alterations in ribosomal proteins S4 and S5 on translational accuracy, ribosomal RNA processing, and ribosome assembly
An investigation into the effects of alterations in ribosomal proteins S4 and S5 on translational accuracy, ribosomal RNA processing, and ribosome assembly Open
Accurate translation of genetic message is an essential step in gene expression and is carried out by the ribosome. Ribosomal proteins S4 and S5 are critical for the decoding and the assembly processes on the ribosome. The interaction betw…