Dmitry Ayollo
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View article: Rapid and Efficient Quality Control Analysis of Isolated Mitochondria by Interferometric Light Microscopy
Rapid and Efficient Quality Control Analysis of Isolated Mitochondria by Interferometric Light Microscopy Open
Mitochondrial transplantation is a promising biotherapeutic strategy to restore cellular energy homeostasis in diseases associated with mitochondrial dysfunction. However, its clinical translation is hindered by the lack of rapid, reliable…
View article: Therapeutic potential of human mesenchymal stromal cell-derived mitochondria in a rat model of post-surgical digestive fistula: towards an energetic nano-biotherapy
Therapeutic potential of human mesenchymal stromal cell-derived mitochondria in a rat model of post-surgical digestive fistula: towards an energetic nano-biotherapy Open
Background Tissue regeneration heavily relies on cellular energy production, with mitochondria playing a crucial role. Dysfunctional mitochondria are implicated in various degenerative diseases, driving interest in targeting mitochondrial …
View article: In Vivo Monitoring and Magnetically‐Enhanced Delivery of CAR T‐Cells to Solid Tumor
In Vivo Monitoring and Magnetically‐Enhanced Delivery of CAR T‐Cells to Solid Tumor Open
Chimeric antigen receptor (CAR) T‐cell therapy demonstrates efficacy for the treatment of hematologic cancers, but remains challenging in solid tumors because of the hostile tumor microenvironment and heterogeneity that restrict the infilt…
View article: Self‐Organization of Long‐Lasting Human Endothelial Capillary‐Like Networks Guided by DLP Bioprinting
Self‐Organization of Long‐Lasting Human Endothelial Capillary‐Like Networks Guided by DLP Bioprinting Open
Tissue engineering holds great promise for regenerative medicine, drug discovery, and as an alternative to animal models. However, as soon as the dimensions of engineered tissue exceed the diffusion limit of oxygen and nutriments, a necrot…
View article: Self-organization of Long-lasting Human Endothelial Capillary Networks guided by DLP Bioprinting
Self-organization of Long-lasting Human Endothelial Capillary Networks guided by DLP Bioprinting Open
Tissue engineering holds great promise for regenerative medicine, drug discovery and as an alternative to animal models. However, as soon as the dimensions of engineered tissue exceed the diffusion limit of oxygen and nutriments, a necroti…
View article: Construction of functional biliary epithelial branched networks with predefined geometry using digital light stereolithography
Construction of functional biliary epithelial branched networks with predefined geometry using digital light stereolithography Open
Cholangiocytes, biliary epithelial cells, are known to spontaneously self-organize into spherical cysts with a central lumen. In this work, we explore a promising biocompatible stereolithographic approach to encapsulate cholangiocytes into…
View article: Self-Organogenesis from 2D Micropatterns to 3D Biomimetic Biliary Trees
Self-Organogenesis from 2D Micropatterns to 3D Biomimetic Biliary Trees Open
Background and Aims: Globally, liver diseases account for 2 million deaths per year. For those with advanced liver disease the only curative approach is liver transplantation. However, less than 10% of those in need get a liver transplant …
View article: Construction of functional biliary epithelial branched networks with predefined geometry using digital light stereolithography
Construction of functional biliary epithelial branched networks with predefined geometry using digital light stereolithography Open
Cholangiocytes, biliary epithelial cells, are known to spontaneously self-organize into spherical cysts with a central lumen. In this work, we explore a promising biocompatible stereolithographic approach to encapsulate cholangiocytes into…
View article: Self-Organogenesis from 2D Micropatterns to 3D Biomimetic Biliary Trees
Self-Organogenesis from 2D Micropatterns to 3D Biomimetic Biliary Trees Open
Background & Aims: Globally, liver diseases account for 2 million deaths per year. For those with advanced liver disease the only curative approach is liver transplantation. However, less than 10% of those in need get a liver transplan…