Do Hoon Lim
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View article: RADT-04. OPTIMAL CLINICOGENETIC CRITERIA FOR POSTOPERATIVE RE-IRRADIATION IN RECURRENT GLIOBLASTOMA: KROG 21-02
RADT-04. OPTIMAL CLINICOGENETIC CRITERIA FOR POSTOPERATIVE RE-IRRADIATION IN RECURRENT GLIOBLASTOMA: KROG 21-02 Open
Patients with glioblastoma (GBM) often have disease progression after standard temozolomide-based chemoradiation. The benefits and optimal use of re-irradiation (re-RT) following re-operation (re-OP) in recurrent glioblastoma (rGBM) remain…
View article: Pancreatic Irradiation Dose as a Risk Factor for Elevation in Hemoglobin A1c Level and Diabetes Mellitus in Patients with Indolent Gastroduodenal Lymphoma
Pancreatic Irradiation Dose as a Risk Factor for Elevation in Hemoglobin A1c Level and Diabetes Mellitus in Patients with Indolent Gastroduodenal Lymphoma Open
A mean pancreas dose ≥2300 cGy was associated with HbA1c elevation, whereas doses <2300 had minimal effect. Given the established link between higher HbA1c level and increased risk of DM and cardiovascular events, pancreatic dose reduction…
View article: Response‐adapted consolidation therapy strategy for patients with metastatic high‐risk neuroblastoma: Results of the SMC NB‐2014 study
Response‐adapted consolidation therapy strategy for patients with metastatic high‐risk neuroblastoma: Results of the SMC NB‐2014 study Open
Background Tandem high‐dose chemotherapy and autologous stem cell transplantation (HDCT/auto‐SCT) and incorporation of 131 I‐metaiodobenzylguanidine ( 131 I‐MIBG) treatment have shown positive outcomes in high‐risk neuroblastoma. However, …
View article: Long-term effects of local radiotherapy on growth and vertebral features in children with high-risk neuroblastoma
Long-term effects of local radiotherapy on growth and vertebral features in children with high-risk neuroblastoma Open
Background To evaluate the effects of local radiotherapy (RT) on growth, we evaluated the chronological growth profiles and vertebral features of children with high-risk neuroblastoma. Methods Thirty-eight children who received local photo…
View article: Treatment Outcomes after Dose-Escalated Moderately Hypofractionated Radiotherapy for Frail Patients with High-Grade Glioma
Treatment Outcomes after Dose-Escalated Moderately Hypofractionated Radiotherapy for Frail Patients with High-Grade Glioma Open
For high-grade glioma (HGG) patients with old age or poor performance status, hypofractionated radiotherapy (hypoRT) in 10–15 fractions is recommended. Also, limited data exist on the impact of salvage treatment after progression in frail …
View article: Tandem High-Dose Chemotherapy Increases the Risk of Secondary Malignant Neoplasm in Pediatric Solid Tumors
Tandem High-Dose Chemotherapy Increases the Risk of Secondary Malignant Neoplasm in Pediatric Solid Tumors Open
Purpose This study aimed to investigate the incidence and risk factors for secondary malignant neoplasms (SMN) in pediatric solid tumors, focusing on the effects of tandem high-dose chemotherapy (HDCT).Materials and Methods Patients (aged …
View article: Long-term effects of local radiotherapy on growth and vertebral features in children with high-risk neuroblastoma
Long-term effects of local radiotherapy on growth and vertebral features in children with high-risk neuroblastoma Open
Objectives: To evaluate the effects of local radiotherapy (RT) on growth, we evaluated the chronological growth profiles and vertebral features of children with high-risk neuroblastoma. Materials and Methods: Thirty-eight children who rece…
View article: Localized intracranial germinoma: is it time to re-define target volume for whole ventricular irradiation?
Localized intracranial germinoma: is it time to re-define target volume for whole ventricular irradiation? Open
brain tumors.Therefore, in addition to de-intensifying radiation dose and volume by virtue of randomized trials, more attention should be paid to developing a radiation treatment methodology based on rich clinical experience, such as the s…
View article: Liquid biopsy using cfDNA to predict radiation therapy response in solid tumors
Liquid biopsy using cfDNA to predict radiation therapy response in solid tumors Open
Purpose: This study explored the potential feasibility of cell-free DNA (cfDNA) in monitoring treatment response through the measurement of chromosomal instabilities using I-scores in the context of radiation therapy (RT) for other solid t…
View article: Clinical Outcomes of Moderately Hypofractionated Concurrent Chemoradiotherapy for Newly Diagnosed Glioblastoma
Clinical Outcomes of Moderately Hypofractionated Concurrent Chemoradiotherapy for Newly Diagnosed Glioblastoma Open
HypoRT with 58.5 Gy in 25 fractions could provide comparable oncologic outcomes and significantly reduce the ALC changes. In addition, HypoRT decreased the LDT. Further investigation should be warranted to suggest the significance of reduc…
View article: The Korean Society for Neuro-Oncology (KSNO) Guideline for the Management of Brain Tumor Patients During the Crisis Period: A Consensus Survey About Specific Clinical Scenarios (Version 2023.1)
The Korean Society for Neuro-Oncology (KSNO) Guideline for the Management of Brain Tumor Patients During the Crisis Period: A Consensus Survey About Specific Clinical Scenarios (Version 2023.1) Open
It is imperative that proper medical care for brain tumor patients be sustained and provided, even during the crisis period. The findings of this consensus survey will be a useful reference in determining appropriate treatment options for …
View article: Role of Radiotherapy in Patients With Relapsed Medulloblastoma
Role of Radiotherapy in Patients With Relapsed Medulloblastoma Open
During the last three decades, the management of medulloblastoma (MBL) has made enormous progress with a multidisciplinary approach, incorporating surgery, radiotherapy (RT), and chemotherapy. Despite this improvement, 20%-30% of patients …
View article: The Korean Society for Neuro-Oncology (KSNO) Guideline for the Management of Brain Tumor Patients During the Crisis Period: A Consensus Recommendation Using the Delphi Method (Version 2023.1)
The Korean Society for Neuro-Oncology (KSNO) Guideline for the Management of Brain Tumor Patients During the Crisis Period: A Consensus Recommendation Using the Delphi Method (Version 2023.1) Open
It is crucial that adequate medical care for patients with brain tumors is maintained and provided, even during times of crisis. This guideline will serve as a valuable resource, assisting in the delivery of treatment to brain tumor patien…
View article: Modeling the Mechanical Microenvironment of Coiled Cerebral Aneurysms
Modeling the Mechanical Microenvironment of Coiled Cerebral Aneurysms Open
Successful occlusion of cerebral aneurysms using coil embolization is contingent upon stable thrombus formation, and the quality of the thrombus depends upon the biomechanical environment. The goal of this study was to investigate how coil…
View article: E-191 Influence of socioeconomic factors on the development of post-stroke depression in aneurysmal subarachnoid hemorrhage survivors
E-191 Influence of socioeconomic factors on the development of post-stroke depression in aneurysmal subarachnoid hemorrhage survivors Open
Introduction/Proposal The risk of developing depression based on the severity and location of injury and patient demographic factors is widely studied for ischemic stroke, but not well characterized for aneurysmal subarachnoid hemorrhage (…
View article: Clinical Significance of Preoperative Hematological Parameters in Patients with D2-Resected, Node-Positive Stomach Cancer
Clinical Significance of Preoperative Hematological Parameters in Patients with D2-Resected, Node-Positive Stomach Cancer Open
The purpose of the present study was to investigate the clinical significance of preoperative hematological parameters in patients with advanced stomach cancer, and to explore who might benefit from adjuvant concurrent chemoradiotherapy (C…
View article: Current trend of radiotherapy for glioblastoma in the elderly: a survey study by the brain tumor Committee of the Korean Radiation Oncology Group (KROG 21–05)
Current trend of radiotherapy for glioblastoma in the elderly: a survey study by the brain tumor Committee of the Korean Radiation Oncology Group (KROG 21–05) Open
Background To investigate the current variability in radiotherapy practice for elderly glioblastoma patients. Methods A questionnaire comprising general information on elderly glioblastoma, treatment selection, radiotherapy and 16 clinical…
View article: Suggestions for Escaping the Dark Ages for Pediatric Diffuse Intrinsic Pontine Glioma Treated with Radiotherapy: Analysis of Prognostic Factors from the National Multicenter Study
Suggestions for Escaping the Dark Ages for Pediatric Diffuse Intrinsic Pontine Glioma Treated with Radiotherapy: Analysis of Prognostic Factors from the National Multicenter Study Open
PurposeThis multicenter retrospective study aimed to investigate clinical, radiologic, and treatment-related factors affecting survival in patients with newly diagnosed diffuse intrinsic pontine glioma (DIPG) treated with radiotherapy.Mate…
View article: Recent Updates on Radiation Therapy for Pediatric Optic Pathway Glioma
Recent Updates on Radiation Therapy for Pediatric Optic Pathway Glioma Open
Optic pathway glioma (OPG) is a rare tumor located in optic nerve, optic tract, or optic chiasm. Treatment options for OPG include surgery, radiation therapy (RT), and chemotherapy. Although RT may provide favorable long-term outcomes in m…
View article: Risk Stratification of Childhood Medulloblastoma Using Integrated Diagnosis: Discrepancies with Clinical Risk Stratification
Risk Stratification of Childhood Medulloblastoma Using Integrated Diagnosis: Discrepancies with Clinical Risk Stratification Open
The new risk stratification incorporating integrated diagnosis showed some discrepancies with clinical risk stratification. Risk stratification based on precise molecular subgrouping is needed for the tailored treatment of MB patients.