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View article: Heart rate response to transient hypoxia in patients with heart failure and Cheyne–Stokes respiration
Heart rate response to transient hypoxia in patients with heart failure and Cheyne–Stokes respiration Open
Gian Domenico Pinna, Elena Robbi, Maria Teresa La Rovere, Roberto Maestri · 2025
Cheyne–Stokes respiration (CSR), a rhythmic rise and fall in ventilation often experienced by patients with heart failure during sleep, is typically accompanied by an oscillation in heart rate (HR) at the same frequency. The mechanisms res…
View article: Robot-Based Assessment of Sitting Balance: Muscular Responses to Self- and Externally-Controlled Perturbations in Seated Position
Robot-Based Assessment of Sitting Balance: Muscular Responses to Self- and Externally-Controlled Perturbations in Seated Position Open
Giorgia Marchesi, Valentina Squeri, Amy Bellitto, Gian Domenico Pinna, Camilla Pierella , et al. · 2025
In the field of rehabilitation, traditional methods for assessing and training core stability and trunk control involve exercises targeting breathing, muscle strengthening, and both static and dynamic balance. Recently, a novel approach us…
View article: INTRODUCTION OF LUNG ULTRASONOGRAPHY (LUS) AS A DIAGNOSTIC TOOL IN THE REHABILITATION OF POST–CARDIAC SURGERY PATIENTS WITH PLEURAL EFFUSION
INTRODUCTION OF LUNG ULTRASONOGRAPHY (LUS) AS A DIAGNOSTIC TOOL IN THE REHABILITATION OF POST–CARDIAC SURGERY PATIENTS WITH PLEURAL EFFUSION Open
Marta Lovagnini, Daniela Rossi, Angelo Caporotondi, Giampaolo Guazzotti, Giovanni Forni , et al. · 2024
Background Pleural effusion (PE) is a common complication after cardiac surgery and is associated with postoperative heart failure and adverse outcomes. Lung ultrasound (LU) has been shown to be more accurate than chest x–ray (CXR) in the …
View article: Data from study: EffecTs of tRanscutaneous vAgus Nerve Stimulation in heart Failure patients with moderately rEduced or preseRved left ventricular function (TRANSFER Trial)
Data from study: EffecTs of tRanscutaneous vAgus Nerve Stimulation in heart Failure patients with moderately rEduced or preseRved left ventricular function (TRANSFER Trial) Open
Roberto Maestri, Maria Teresa La Rovere, Gian Domenico Pinna · 2024
Data pertaining to single-blind, randomised, cross-over studies: 1) TVNS_AIM_1_Trial_1 to compare the acute effect of left tVNS at 25 Hz and 10 Hz, 2) TVNS_AIM_1_Trial_2 to compare the acute effect of left and right tVNS at the best freque…
View article: Data from study: EffecTs of tRanscutaneous vAgus Nerve Stimulation in heart Failure patients with moderately rEduced or preseRved left ventricular function (TRANSFER Trial)
Data from study: EffecTs of tRanscutaneous vAgus Nerve Stimulation in heart Failure patients with moderately rEduced or preseRved left ventricular function (TRANSFER Trial) Open
Roberto Maestri, Maria Teresa La Rovere, Gian Domenico Pinna · 2024
Data pertaining to single-blind, randomised, cross-over studies: 1) TVNS_AIM_1_Trial_1 to compare the acute effect of left tVNS at 25 Hz and 10 Hz, 2) TVNS_AIM_1_Trial_2 to compare the acute effect of left and right tVNS at the best freque…
View article: P-160 Mismatch repair system protein deficiency as a resistance factor for locally advanced rectal adenocarcinoma patients receiving neoadjuvant chemo-radiotherapy
P-160 Mismatch repair system protein deficiency as a resistance factor for locally advanced rectal adenocarcinoma patients receiving neoadjuvant chemo-radiotherapy Open
Andrea Pretta, Pina Ziranu, Riccardo Giampieri, Gian Domenico Pinna, Giovanni Randon , et al. · 2023
View article: Functional mapping: a new approach for substrate characterization in patients affected by atrial fibrillation
Functional mapping: a new approach for substrate characterization in patients affected by atrial fibrillation Open
Gian Domenico Pinna, B Grossi, Carlo Ceriotti, Antonio Taormina, Lidia Poggio , et al. · 2023
Funding Acknowledgements Type of funding sources: None. Background The ongoing challenge is to generate meaningful data during electrophysiological (EP) studies, integrating the knowledge on atrial fibrillation (AF) progression gained by t…
View article: Baroreceptor Sensitivity in Individuals with CKD and Heart Failure
Baroreceptor Sensitivity in Individuals with CKD and Heart Failure Open
David M. Charytan, Qandeel H. Soomro, Angelo Caporotondi, Giampaolo Guazzotti, Roberto Maestri , et al. · 2022
Key Points We found that cardiac baroreceptor sensitivity (BRS), which reflects the integrity of autonomic responses to changes in BP, was depressed in individuals with both CKD and heart failure compared with those with heart failure and …
View article: Effect of Algorithmic Music Listening on Cardiac Autonomic Nervous System Activity: An Exploratory, Randomized Crossover Study
Effect of Algorithmic Music Listening on Cardiac Autonomic Nervous System Activity: An Exploratory, Randomized Crossover Study Open
Alfredo Raglio, Roberto Maestri, Elena Robbi, Antonia Pierobon, Maria Teresa La Rovere , et al. · 2022
It is proven that music listening can have a therapeutic impact in many clinical fields. However, to assume a curative value, musical stimuli should have a therapeutic logic. This study aimed at assessing short-term effects of algorithmic …
View article: P112 REPRODUCIBILITY AND AGREEMENT OF 2D VS M–MODE ECHOCARDIOGRAPHIC LINEAR MEASUREMENTS IN ESTIMATION OF LEFT VENTRICLE MASS IN NORMAL ADULT SUBJECTS
P112 REPRODUCIBILITY AND AGREEMENT OF 2D VS M–MODE ECHOCARDIOGRAPHIC LINEAR MEASUREMENTS IN ESTIMATION OF LEFT VENTRICLE MASS IN NORMAL ADULT SUBJECTS Open
D Rossi, F Alessi, C Campanile, Gian Domenico Pinna, Giovanni Forni · 2022
Background: Left ventricle (LV) mass is one of the echocardiographic parameters, essentials to define the LV remodeling
View article: Computer-Assisted Assessment of the Interaction Between Arousals, Breath-by-Breath Ventilation, and Chemical Drive During Cheyne-Stokes Respiration in Heart Failure Patients
Computer-Assisted Assessment of the Interaction Between Arousals, Breath-by-Breath Ventilation, and Chemical Drive During Cheyne-Stokes Respiration in Heart Failure Patients Open
Gian Domenico Pinna, Roberto Maestri · 2022
Transient increases in ventilation induced by arousal from sleep during Cheyne-Stokes respiration in heart failure patients are thought to contribute to sustaining and exacerbating the ventilatory oscillation. The only possibility to inves…
View article: Lack of association between heart period variability asymmetry and respiratory sinus arrhythmia in healthy and chronic heart failure individuals
Lack of association between heart period variability asymmetry and respiratory sinus arrhythmia in healthy and chronic heart failure individuals Open
Beatrice De Maria, Laura Adelaide Dalla Vecchia, Roberto Maestri, Gian Domenico Pinna, Monica Parati , et al. · 2022
Dataset from De Maria B, Dalla Vecchia LA, Maestri R, Pinna GD, Parati M, Perego F, Bari V, Cairo B, Gelpi F, La Rovere MT, Porta A. Lack of association between heart period variability asymmetry and respiratory sinus arrhythmia in healthy…
View article: Lack of association between heart period variability asymmetry and respiratory sinus arrhythmia in healthy and chronic heart failure individuals
Lack of association between heart period variability asymmetry and respiratory sinus arrhythmia in healthy and chronic heart failure individuals Open
Beatrice De Maria, Laura Adelaide Dalla Vecchia, Roberto Maestri, Gian Domenico Pinna, Monica Parati , et al. · 2022
Dataset from De Maria B, Dalla Vecchia LA, Maestri R, Pinna GD, Parati M, Perego F, Bari V, Cairo B, Gelpi F, La Rovere MT, Porta A. Lack of association between heart period variability asymmetry and respiratory sinus arrhythmia in healthy…
View article: Interaction Between Arousals and Ventilation During Cheyne-Stokes Respiration in Heart Failure Patients: Insights From Breath-by-Breath Analysis
Interaction Between Arousals and Ventilation During Cheyne-Stokes Respiration in Heart Failure Patients: Insights From Breath-by-Breath Analysis Open
Gian Domenico Pinna, Elena Robbi, Claudio Bruschi, Maria Teresa La Rovere, Roberto Maestri · 2021
Study Objectives: Arousals from sleep during the hyperpneic phases of Cheyne-Stokes respiration with central sleep apnea (CSR-CSA) in patients with heart failure are thought to cause ventilatory overshoot and a consequent longer apnea, the…
View article: Thyroid cancer in Sardinian pediatric patients: report of 63 cases and a review of the literature
Thyroid cancer in Sardinian pediatric patients: report of 63 cases and a review of the literature Open
Michela Lai, A. Satta, Gian Domenico Pinna, L.M. Altana, G. Senes , et al. · 2021
8%), according to the last WHO classification.Autoimmune thyroid diseases were detected in the 29 PTCs (64% of PTCs).BRAF V600E mutation was found in 21 PTCs (47% of PTCs).Our study shows that thyroid cancer in Sardinian children and adole…
View article: Determinants of Sleepiness at Wheel and Missing Accidents in Patients With Obstructive Sleep Apnea
Determinants of Sleepiness at Wheel and Missing Accidents in Patients With Obstructive Sleep Apnea Open
Francesco Fanfulla, Gian Domenico Pinna, Oreste Marrone, Nadia D’Artavilla Lupo, Simona Arcovio , et al. · 2021
Study Objectives Motor-vehicle crashes are frequent in untreated OSA patients but there is still uncertainty on prevalence as well as physiological or clinical determinants of sleepiness at the wheel (SW) in OSA patients. We assessed deter…
View article: Lack of association between heart period variability asymmetry and respiratory sinus arrhythmia in healthy and chronic heart failure individuals
Lack of association between heart period variability asymmetry and respiratory sinus arrhythmia in healthy and chronic heart failure individuals Open
Beatrice De Maria, Laura Adelaide Dalla Vecchia, Roberto Maestri, Gian Domenico Pinna, Monica Parati , et al. · 2021
Temporal asymmetry is a peculiar aspect of heart period (HP) variability (HPV). HPV asymmetry (HPVA) is reduced with aging and pathology, but its origin is not fully elucidated. Given the impact of respiration on HPV resulting in the respi…
View article: Dataset related to article: "Quantitative assessment of the quality of home sleep studies: A computer‐assisted approach"
Dataset related to article: "Quantitative assessment of the quality of home sleep studies: A computer‐assisted approach" Open
Roberto Maestri, Elena Robbi, Marta Lovagnini, Anna Eugenia Taurino, Francesco Fanfulla , et al. · 2020
Home monitoring is the most practical means of collecting sleep data in large-scale research investigations. Because the portion of recording time with poor-quality data is higher than in attended polysomnography, a quantitative assessment…
View article: Dataset related to article: "Quantitative assessment of the quality of home sleep studies: A computer‐assisted approach"
Dataset related to article: "Quantitative assessment of the quality of home sleep studies: A computer‐assisted approach" Open
Roberto Maestri, Elena Robbi, Marta Lovagnini, Anna Eugenia Taurino, Francesco Fanfulla , et al. · 2020
Home monitoring is the most practical means of collecting sleep data in large-scale research investigations. Because the portion of recording time with poor-quality data is higher than in attended polysomnography, a quantitative assessment…
View article: Upper Limb Interactive Weightless Technology-Aided Intervention and Assessment Picks Out Motor Skills Improvement in Parkinson's Disease: A Pilot Study
Upper Limb Interactive Weightless Technology-Aided Intervention and Assessment Picks Out Motor Skills Improvement in Parkinson's Disease: A Pilot Study Open
Cira Fundarò, Carlo Cavalieri, Gian Domenico Pinna, Anna Giardini, Francesca Mancini , et al. · 2020
Background: In Parkinson's disease, reaching movements are conditioned by motor planning and execution deficiency. Recently, rehabilitation, aided by high technological devices, was employed for Parkinson's disease. Objective:
View article: Quantitative assessment of the quality of home sleep studies: A computer‐assisted approach
Quantitative assessment of the quality of home sleep studies: A computer‐assisted approach Open
Roberto Maestri, Elena Robbi, Marta Lovagnini, Anna Eugenia Taurino, Francesco Fanfulla , et al. · 2019
Home monitoring is the most practical means of collecting sleep data in large‐scale research investigations. Because the portion of recording time with poor‐quality data is higher than in attended polysomnography, a quantitative assessment…
View article: Cardiac and Peripheral Autonomic Responses to Orthostatic Stress During Transcutaneous Vagus Nerve Stimulation in Healthy Subjects
Cardiac and Peripheral Autonomic Responses to Orthostatic Stress During Transcutaneous Vagus Nerve Stimulation in Healthy Subjects Open
Eleonora Tobaldini, Edgar Toschi‐Dias, Liliane Appratto de Souza, Karina Rabello Casali, Marco Vicenzi , et al. · 2019
Previous studies showed that transcutaneous vagus nerve stimulation (tVNS) modulates the autonomic nervous system (ANS) in resting condition. However, the autonomic regulation in response to an orthostatic challenge during tVNS in healthy …
View article: Paced Breathing Increases the Redundancy of Cardiorespiratory Control in Healthy Individuals and Chronic Heart Failure Patients
Paced Breathing Increases the Redundancy of Cardiorespiratory Control in Healthy Individuals and Chronic Heart Failure Patients Open
Alberto Porta, Roberto Maestri, Vlasta Bari, Beatrice De Maria, Beatrice Cairo , et al. · 2018
Synergy and redundancy are concepts that suggest, respectively, adaptability and fault tolerance of systems with complex behavior. This study computes redundancy/synergy in bivariate systems formed by a target X and a driver Y according to…
View article: Physiological and clinical characteristics of patients with COPD admitted to an inpatient pulmonary rehabilitation program: A real-life study
Physiological and clinical characteristics of patients with COPD admitted to an inpatient pulmonary rehabilitation program: A real-life study Open
Roberto Maestri, Claudio Bruschi, C. Fracchia, Gian Domenico Pinna, Francesco Fanfulla , et al. · 2018
Confirming data of literature, this real-life study shows the characteristics of COPD patients undergoing an inpatient PRP with significant improvement in exercise capacity, independent of whether in stable state or after a recent exacerba…
View article: Daytime periodic breathing during short‐term laboratory recordings in heart failure patients: the iceberg tip of central sleep apnoea?
Daytime periodic breathing during short‐term laboratory recordings in heart failure patients: the iceberg tip of central sleep apnoea? Open
Maria Teresa La Rovere, Roberto Maestri, Elena Robbi, Angelo Caporotondi, Giampaolo Guazzotti , et al. · 2017
Sleep-disordered breathing (SDB) is a highly prevalent co-morbidity in patients with heart failure (HF) and can manifest as both obstructive (OSA) and central sleep apnoea (CSA).1 The latter shows a typical periodic breathing pattern (waxi…
View article: P01.08 miRNAs in serum exosomes, as reliable non-invasive biomarkers to facilitate the clinical management of patients with gliomas
P01.08 miRNAs in serum exosomes, as reliable non-invasive biomarkers to facilitate the clinical management of patients with gliomas Open
Alessandra Santangelo, Gian Domenico Pinna, Mario Meglio, Francesco Sala, Giuseppe Lippi , et al. · 2017
Malignant gliomas and mainly glioblastoma multiforme (GBM) are the most lethal primary brain tumors. Considering that the new (2016) classification of central nervous system tumors of World Health Organization proposes an integrated diagno…
View article: Third phase of cardiac rehabilitation: a nurse-based “home-control†model
Third phase of cardiac rehabilitation: a nurse-based “home-control†model Open
Sara Albertini, Antonella Ciocca, Cristina Opasich, Gian Domenico Pinna, Franco Cobelli · 2015
Background. Phase 3 is a critical point for cardiac rehabilitation: many problems don’t allow achieving a correct secondary prevention, in particular regarding the relationship between patient and cardiologist. Aiming at ensuring continu…
View article: Differential impact of body position on the severity of disordered breathing in heart failure patients with obstructive vs. central sleep apnoea
Differential impact of body position on the severity of disordered breathing in heart failure patients with obstructive vs. central sleep apnoea Open
Gian Domenico Pinna, Elena Robbi, Maria Teresa La Rovere, Anna Eugenia Taurino, Claudio Bruschi , et al. · 2015
Aims Obstructive ( OSA ) and central sleep apnoea ( CSA ) are a common comorbidity in patients with heart failure. The purpose of this study was to assess and compare the impact of body position on the severity of sleep apnoea in these two…
View article: Medicinal clays improve the endurance of loaded inspiratory muscles in COPD: a randomized clinical trial of nonpharmacological treatment
Medicinal clays improve the endurance of loaded inspiratory muscles in COPD: a randomized clinical trial of nonpharmacological treatment Open
S. Baldi, Gian Domenico Pinna, Claudio Bruschi, Fabiana Ribeiro Caldara, Elena Dacosto , et al. · 2015
MBT model improves ET upon a moderate IRB challenge, indicating the occurrence of a training effect. The LnVO2Endur/ΔIL-6 suggests a physiologic adaptive mechanism in respiratory muscles of COPD patients allocated to treatment. Both therma…
View article: Pre-Discharge Evaluation in Heart Failure – Additive Predictive Value of the 6-Minute Walking Test to Clinical Scores –
Pre-Discharge Evaluation in Heart Failure – Additive Predictive Value of the 6-Minute Walking Test to Clinical Scores – Open
Maria Teresa La Rovere, Roberto Maestri, Angelo Caporotondi, Daniela Corbellini, Giampaolo Guazzotti , et al. · 2015
In HF patients, a pre-discharge evaluation combining the 6MWT to clinical scores improves prediction of 12-month mortality.




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