Dominik Denzel
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View article: Autoantibodies in patients with obsessive-compulsive disorder: a systematic review
Autoantibodies in patients with obsessive-compulsive disorder: a systematic review Open
Obsessive-compulsive disorder (OCD) is a frequent and debilitating mental illness. Although efficacious treatment options are available, treatment resistance rates are high. Emerging evidence suggests that biological components, especially…
View article: Reduced structural connectivity in the corpus callosum in patients with anorexia nervosa
Reduced structural connectivity in the corpus callosum in patients with anorexia nervosa Open
Objective Previous diffusion tensor imaging studies reported a reduced fractional anisotropy in the body of the corpus callosum in patients with anorexia nervosa, which may indicate impaired white matter integrity in interhemispheric conne…
View article: Immunological causes of obsessive-compulsive disorder: is it time for the concept of an “autoimmune OCD” subtype?
Immunological causes of obsessive-compulsive disorder: is it time for the concept of an “autoimmune OCD” subtype? Open
View article: Anti-MOG autoantibody-associated schizophreniform psychosis
Anti-MOG autoantibody-associated schizophreniform psychosis Open
Objectives: Autoimmune mechanisms are related to disease development in a subgroup of patients with psychosis. The contribution of immunoglobulin G (IgG) antibodies against myelin oligodendrocyte glycoprotein (MOG) is mainly unclear in thi…
View article: Upregulation of sICAM-1 and sVCAM-1 Levels in the Cerebrospinal Fluid of Patients with Schizophrenia Spectrum Disorders
Upregulation of sICAM-1 and sVCAM-1 Levels in the Cerebrospinal Fluid of Patients with Schizophrenia Spectrum Disorders Open
Immunological explanatory approaches are becoming increasingly important in schizophrenia research. In this context, the function of the blood-brain barrier (BBB) and the blood-cerebrospinal fluid (CSF) barrier (BCSFB) plays an essential r…
View article: Increased GFAP concentrations in the cerebrospinal fluid of patients with unipolar depression
Increased GFAP concentrations in the cerebrospinal fluid of patients with unipolar depression Open
Inflammatory processes involving altered microglial activity may play a relevant role in the pathophysiology of depressive disorders. Glial fibrillary acidic protein (GFAP) and calcium-binding protein S100B are considered microglial marker…
View article: Upregulation of sICAM-1 and sVCAM-1 Levels in the Cerebrospinal Fluid of Patients with Schizophrenia Spectrum Disorders
Upregulation of sICAM-1 and sVCAM-1 Levels in the Cerebrospinal Fluid of Patients with Schizophrenia Spectrum Disorders Open
IntroductionImmunological explanatory approaches are becoming increasingly important in schizophrenia research. In this context, the function of the blood–brain barrier (BBB) and the blood–cerebrospinal fluid (CSF) barrier (BCSFB) play an …
View article: Sex difference in cerebrospinal fluid/blood albumin quotients in patients with schizophreniform and affective psychosis
Sex difference in cerebrospinal fluid/blood albumin quotients in patients with schizophreniform and affective psychosis Open
View article: Novel Antineuronal Autoantibodies With Somatodendritic Staining Pattern in a Patient With Autoimmune Psychosis
Novel Antineuronal Autoantibodies With Somatodendritic Staining Pattern in a Patient With Autoimmune Psychosis Open
The patient probably suffered from autoantibody-associated autoimmune psychosis. The special features of the case were that the patient (1) presented with mostly inconspicuous basic diagnostics, except for the altered EEG in combination wi…
View article: Cerebrospinal Fluid Findings of 36 Adult Patients with Autism Spectrum Disorder
Cerebrospinal Fluid Findings of 36 Adult Patients with Autism Spectrum Disorder Open
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by difficulties with social interaction, repetitive behavior, and additional features, such as special interests. Its precise etiology is unclear. Recentl…
View article: Anti-N-Methyl-D-Aspartate-Receptor Encephalitis: A 10-Year Follow-Up
Anti-N-Methyl-D-Aspartate-Receptor Encephalitis: A 10-Year Follow-Up Open
Anti-inflammatory treatment led to almost full recovery with persistent disappearance of catatonic symptoms; however, a dysexecutive syndrome led to ongoing relevant problems with good response to low-dose atypical neuroleptics and CBT. Th…
View article: Author response for "Local glutamate in cingulate cortex subregions differentially correlates with affective network activations during face perception"
Author response for "Local glutamate in cingulate cortex subregions differentially correlates with affective network activations during face perception" Open
View article: fMRI Revealed Reduced Amygdala Activation after Nx4 in Mildly to Moderately Stressed Healthy Volunteers in a Randomized, Placebo-Controlled, Cross-Over Trial
fMRI Revealed Reduced Amygdala Activation after Nx4 in Mildly to Moderately Stressed Healthy Volunteers in a Randomized, Placebo-Controlled, Cross-Over Trial Open
View article: Datapoints
Datapoints Open
Datapoints for figures
View article: Testtest.xlsx
Testtest.xlsx Open
test test
View article: Glutamate in Salience Network Predicts BOLD Response in Default Mode Network During Salience Processing
Glutamate in Salience Network Predicts BOLD Response in Default Mode Network During Salience Processing Open
During picture processing, the extent of deactivation in the Posterior Cingulate Cortex (PCC) was attenuated by two different salience attributions: sexual content and unexpectedness of emotional content. Our results indicate that stimulus…
View article: Expectation of sexual images of adults and children elicits differential dorsal anterior cingulate cortex activation in pedophilic sexual offenders and healthy controls
Expectation of sexual images of adults and children elicits differential dorsal anterior cingulate cortex activation in pedophilic sexual offenders and healthy controls Open
View article: Glutamate and GABA measured in the aMCC influence resting state activity in the extended salience network
Glutamate and GABA measured in the aMCC influence resting state activity in the extended salience network Open
View article: Histoarchitectonically distinct regions of anterior cingulate show altered glutamatergic metabolism in major depressive disorder
Histoarchitectonically distinct regions of anterior cingulate show altered glutamatergic metabolism in major depressive disorder Open
Increasing evidence suggests a hypoglutamatergic state in major depressive disorder (MDD), however spatial- and metabolite specific abnormalities have not been fully characterized. Using short TE/TM STEAM MRS, we evaluated Glu, Gln, Gln/Gl…