Dominik Weis
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View article: Effect of Microscopic Properties on Flow Behavior of Industrial Cohesive Powder
Effect of Microscopic Properties on Flow Behavior of Industrial Cohesive Powder Open
The characteristics of powders on a bulk scale are heavily influenced by both the material properties and the size of their primary particles. Throughout the stages of storage and transportation in the powder processing industry, various f…
View article: Stirrer design for improving fluidization of cohesive powder: A time-resolved X-ray study
Stirrer design for improving fluidization of cohesive powder: A time-resolved X-ray study Open
View article: Describing the Drying and Solidification Behavior of Single Suspension Droplets Using a Novel Unresolved CFD-DEM Simulation Approach
Describing the Drying and Solidification Behavior of Single Suspension Droplets Using a Novel Unresolved CFD-DEM Simulation Approach Open
With increasing computational capacities and advances in numerical methods, a simulation-based process and product design approach for spray dried products has become the focus of many researchers. In this context, a novel unresolved CFD-D…
View article: Time-resolved X-ray study of assisted fluidization of cohesive micron powder: On the role of mechanical vibration
Time-resolved X-ray study of assisted fluidization of cohesive micron powder: On the role of mechanical vibration Open
Mechanical vibration has been broadly used to assist fluidization of cohesive powders, because of its capability to disrupt gas channels and agglomerates. However, the improvement reported in literature is mostly deduced from bulk response…
View article: Use of Multiscale Data-Driven Surrogate Models for Flowsheet Simulation of an Industrial Zeolite Production Process
Use of Multiscale Data-Driven Surrogate Models for Flowsheet Simulation of an Industrial Zeolite Production Process Open
The production of catalysts such as zeolites is a complex multiscale and multi-step process. Various material properties, such as particle size or moisture content, as well as operating parameters—e.g., temperature or amount and compositio…
View article: Elucidation of mass transfer mechanisms in pellet formation by spheronization
Elucidation of mass transfer mechanisms in pellet formation by spheronization Open
Previously published mechanisms of pellet formation during extrusion-spheronization include a transfer of material between different granules. This research aimed to specify the origin of this transfered mass, enabling further insight into…
View article: The sustainable synthesis of levetiracetam by an enzymatic dynamic kinetic resolution and an <i>ex-cell</i> anodic oxidation
The sustainable synthesis of levetiracetam by an enzymatic dynamic kinetic resolution and an <i>ex-cell</i> anodic oxidation Open
Levetiracetam is an active pharmaceutical ingredient widely used to treat epilepsy.
View article: Frontispiece: The “Green” Electrochemical Synthesis of Periodate
Frontispiece: The “Green” Electrochemical Synthesis of Periodate Open
Periodate Boron-doped diamond anodes enable the direct electrochemical synthesis of periodate from iodide, as reported by S. R. Waldvogel et al. in their Communication on page 8036. This periodate can then be used for the cost-efficient sy…
View article: The “Green” Electrochemical Synthesis of Periodate
The “Green” Electrochemical Synthesis of Periodate Open
High‐grade periodate is relatively expensive, but is required for many sensitive applications such as the synthesis of active pharmaceutical ingredients. These high costs originate from using lead dioxide anodes in contemporary electrochem…
View article: Die “grüne” elektrochemische Synthese von Periodat
Die “grüne” elektrochemische Synthese von Periodat Open
Hochreines Periodat ist relativ teuer, wird jedoch für viele anspruchsvolle Anwendungen, wie zur Synthese von Pharmawirkstoffen (API) benötigt. Die hohen Kosten entstehen durch die Verwendung von Bleidioxid‐Anoden und durch den Einsatz von…
View article: Contact Behavior of Microcrystalline Cellulose Pellets Depending on their Water Content
Contact Behavior of Microcrystalline Cellulose Pellets Depending on their Water Content Open
Microcrystalline cellulose pellets for oral drug delivery are often produced by a combined wet extrusion‐spheronization process. During the entire process, the cylindrical as well as the spherical pellets are exposed to various stresses re…
View article: Particle Kinematics in Spheronization of Pharmaceutical Pellets
Particle Kinematics in Spheronization of Pharmaceutical Pellets Open
Research Article: For the successful operation of solid oxide fuel cells with biogas, it is essential to remove hydrogen sulfide.Breakthrough data for three different commercially available adsorbents at various gas compositions were colle…
View article: Simulation study of the discharge characteristics of silos with cohesive particles
Simulation study of the discharge characteristics of silos with cohesive particles Open
\nIn many industrial applications the silo for bulk materials is an important part of an overall process. Silos are used for instance to buffer intermediate products to ensure a continuous supply for the next process step. This study deals…
View article: Effect of the particle shape on the particle dynamics in a spheronization process
Effect of the particle shape on the particle dynamics in a spheronization process Open
Spherical granules with a narrow size distribution are widely used in many pharmaceutical applications. Extrusion-spheronization is a well-established process to produce such pharmaceutical pellets. The cylindrical extrudates from the extr…
View article: DEM simulations of particle dynamics in a spheronization process to describe the pelletization mechanisms
DEM simulations of particle dynamics in a spheronization process to describe the pelletization mechanisms Open
Spheronization is an important process to produce pharmaceutical pellets with a narrow particle size distribution and a homogeneous outer particle surface. Thereby, cylindrical extrudates are rounded by different pelletization mechanisms […