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View article: Enzymatic biofuel cell on flexible nanoporous gold electrodes
Enzymatic biofuel cell on flexible nanoporous gold electrodes Open
A glucose/O2-based biofuel cell employing nanoporous gold electrodes (NPG) supported by Kapton® was prepared. The anode was prepared by drop-casting a solution of Crassicarpon hotsonii cellobiose dehydrogenase (ChCDH) and an Os complex-bas…
View article: Development of flexible nanoporous gold electrodes for the detection of glucose
Development of flexible nanoporous gold electrodes for the detection of glucose Open
The development of implantable glucose sensors is of significant interest in the management of diabetes. This work focuses on developing an implantable, biocompatible nanoporous gold electrode prototype based on Kapton® for the subcutaneou…
View article: Effects of Sterilization on Cellobiose Dehydrogenase and Glucose Oxidase Based Glucose Biosensors
Effects of Sterilization on Cellobiose Dehydrogenase and Glucose Oxidase Based Glucose Biosensors Open
Research on implantable glucose biosensors is driven by the need for innovative medical devices for continuous glucose monitoring in patients with diabetes mellitus. However, biosensor sterilization is a step that is widely omitted during …
View article: Effect of Protection Polymer Coatings on the Performance of an Amperometric Galactose Biosensor in Human Plasma
Effect of Protection Polymer Coatings on the Performance of an Amperometric Galactose Biosensor in Human Plasma Open
Galactose monitoring in individuals allows the prevention of harsh health conditions related to hereditary metabolic diseases like galactosemia. Current methods of galactose detection need development to obtain cheaper, more reliable, and …
View article: Tailoring Water-Based Graphite Conductive Ink Formulation for Enzyme Stencil-Printing: Experimental Design to Enhance Wearable Biosensor Performance
Tailoring Water-Based Graphite Conductive Ink Formulation for Enzyme Stencil-Printing: Experimental Design to Enhance Wearable Biosensor Performance Open
Herein, we report for the first time an experimental design-based approach to develop water-based graphite conductive ink containing enzymes and redox mediators to obtain fully printed wearable biosensors for lactate and glucose monitoring…
View article: CCDC 2284154: Experimental Crystal Structure Determination
CCDC 2284154: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2284153: Experimental Crystal Structure Determination
CCDC 2284153: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2284155: Experimental Crystal Structure Determination
CCDC 2284155: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Water‐Based Conductive Ink Formulations for Enzyme‐Based Wearable Biosensors
Water‐Based Conductive Ink Formulations for Enzyme‐Based Wearable Biosensors Open
Herein, this work reports the first example of second‐generation wearable biosensor arrays based on a printed electrode technology involving a water‐based graphite ink, for the simultaneous detection of l ‐lactate and d ‐glucose. The water…
View article: Continuous ex vivo glucose sensing in human physiological fluids using an enzymatic sensor in a vein replica
Continuous ex vivo glucose sensing in human physiological fluids using an enzymatic sensor in a vein replica Open
Managing blood glucose can affect important clinical outcomes during the intraoperative phase of surgery. However, currently available instruments for glucose monitoring during surgery are few and not optimized for the specific application…
View article: Cross-Linkable Polymer-Based Multi-layers for Protecting Electrochemical Glucose Biosensors against Uric Acid, Ascorbic Acid, and Biofouling Interferences
Cross-Linkable Polymer-Based Multi-layers for Protecting Electrochemical Glucose Biosensors against Uric Acid, Ascorbic Acid, and Biofouling Interferences Open
The lifetime of implantable electrochemical glucose monitoring devices is limited due to the foreign body response and detrimental effects from ascorbic acid (AA) and uric acid (UA) interferents that are components of physiological media. …
View article: Tethering zwitterionic polymer coatings to mediated glucose biosensor enzyme electrodes can decrease sensor foreign body response yet retain sensor sensitivity to glucose
Tethering zwitterionic polymer coatings to mediated glucose biosensor enzyme electrodes can decrease sensor foreign body response yet retain sensor sensitivity to glucose Open
Foreign body response (FBR) is a major challenge that affects implantable biosensors and medical devices, including glucose biosensors, leading to a deterioration in device response over time. Polymer shields are often used to mitigate thi…
View article: An Oxygen Insensitive Amperometric Glucose Biosensor Based on An Engineered Cellobiose Dehydrogenase: Direct versus Mediated Electron Transfer Responses
An Oxygen Insensitive Amperometric Glucose Biosensor Based on An Engineered Cellobiose Dehydrogenase: Direct versus Mediated Electron Transfer Responses Open
Cellobiose dehydrogenase (CDH) is capable of oxidizing cellobiose and related carbohydrates and generating electrical current at carbon‐based electrodes through direct electron transfer (DET) or mediated electron transfer (MET) mechanisms.…
View article: Self-Powered Detection of Glucose by Enzymatic Glucose/Oxygen Fuel Cells on Printed Circuit Boards
Self-Powered Detection of Glucose by Enzymatic Glucose/Oxygen Fuel Cells on Printed Circuit Boards Open
Monitoring glucose levels in physiological fluids can help prevent severe complications associated with hypo- and hyper-glycemic events. Current glucose-monitoring systems require a three-electrode setup and a power source to function, whi…
View article: Electrochemical glucose biosensor based on an osmium redox polymer and glucose oxidase grafted to carbon nanotubes: A design-of-experiments optimisation of current density and stability
Electrochemical glucose biosensor based on an osmium redox polymer and glucose oxidase grafted to carbon nanotubes: A design-of-experiments optimisation of current density and stability Open
Enzymatic glucose electrodes based on mediated electron transfer have potential for application as semi-implantable or implantable sensors. Enzyme electrodes consisting of adsorbed osmium-based redox polymer crosslinked with a glucose oxid…
View article: Use of a Thermophile Desiccation-Tolerant Cyanobacterial Culture and Os Redox Polymer for the Preparation of Photocurrent Producing Anodes
Use of a Thermophile Desiccation-Tolerant Cyanobacterial Culture and Os Redox Polymer for the Preparation of Photocurrent Producing Anodes Open
Oxygenic photosynthesis conducted by cyanobacteria has dramatically transformed the geochemistry of our planet. These organisms have colonized most habitats, including extreme environments such as the driest warm desert on Earth: the Ataca…
View article: Electroactive biofilms on surface functionalized anodes: the anode respiring behavior of a novel electroactive bacterium,<i>Desulfuromonas acetexigens</i>
Electroactive biofilms on surface functionalized anodes: the anode respiring behavior of a novel electroactive bacterium,<i>Desulfuromonas acetexigens</i> Open
Surface chemistry is known to influence the formation, composition and electroactivity of electron-conducting biofilms with however limited information on the variation of microbial composition and electrochemical response during biofilm d…
View article: Improved operational stability of mediated glucose enzyme electrodes for operation in human physiological solutions
Improved operational stability of mediated glucose enzyme electrodes for operation in human physiological solutions Open
Stability of glucose-oxidising enzyme electrodes is affected by substances in physiological solutions, hampering deployment as long-term implantable biosensors or fuel cells. The performance of Nafion over-coated enzyme electrodes, consist…
View article: Increasing Redox Potential, Redox Mediator Activity, and Stability in a Fungal Laccase by Computer-Guided Mutagenesis and Directed Evolution
Increasing Redox Potential, Redox Mediator Activity, and Stability in a Fungal Laccase by Computer-Guided Mutagenesis and Directed Evolution Open
Fungal high-redox-potential laccases (HRPLs) are multicopper oxidases with a relaxed substrate specificity that is highly dependent on their binding affinity and redox potential of the T1Cu site (ET1). In this study, we combined computatio…
View article: Cover Feature: Use of Polymer Coatings to Enhance the Response of Redox‐Polymer‐Mediated Electrodes (ChemElectroChem 5/2019)
Cover Feature: Use of Polymer Coatings to Enhance the Response of Redox‐Polymer‐Mediated Electrodes (ChemElectroChem 5/2019) Open
The Cover Feature shows the enhancement effect of a second poly(acrylic acid) coating layer on the catalytic response and operational stability of a lactate oxidase/Os redox polymer modified electrode. More information can be found in the …
View article: Multiplexed Electrochemical Cancer Diagnostics With Automated Microfluidics
Multiplexed Electrochemical Cancer Diagnostics With Automated Microfluidics Open
Microfluidic platforms can lead to miniaturisation, increased throughput and reduced reagent consumption, particularly when the processes are automated. Here, a programmable microcontroller is used for automation of a microfluidic platform…
View article: Use of Polymer Coatings to Enhance the Response of Redox‐Polymer‐Mediated Electrodes
Use of Polymer Coatings to Enhance the Response of Redox‐Polymer‐Mediated Electrodes Open
The successful use of biosensors requires that the sensor can operate over abroad enough linear range that encompasses the physiological concentration of the substrate of interest. A polymer coating layer functioning as a mass‐transport ba…