Donald E. Thomas
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View article: P51 First case of lupus: Bishop Eraclius of Liège, Belgium
P51 First case of lupus: Bishop Eraclius of Liège, Belgium Open
Background Around 963 A.D., Bishop Eraclius (Liège, Belgium) wrote an affidavit stating, 'I … was nearly taken to death by the disease called Lupus.' On the seventh night of praying at Saint Martin's tomb (Tours, France), Saints Martin and…
View article: Multivariate inspection of German steel civil infrastructure using autonomous UAS
Multivariate inspection of German steel civil infrastructure using autonomous UAS Open
Aging civil infrastructure and increasing traffic loads lead to deteriorating assets and the need for regular manual inspections, which generally entail at least partial closure of the asset and operational downtime. These costly inspectio…
View article: Peroxisome proliferator activated receptor-γ agonist pioglitazone improves vascular and metabolic dysfunction in systemic lupus erythematosus
Peroxisome proliferator activated receptor-γ agonist pioglitazone improves vascular and metabolic dysfunction in systemic lupus erythematosus Open
NCT02338999.
View article: 1304 Factors in lupus diagnosis
1304 Factors in lupus diagnosis Open
Background Lupus is a complex, chronic autoimmune disease affecting an estimated 1.5 million Americans. Lupus symptoms are heterogeneous. Suboptimal diagnostic tests have contributed to diagnostic delay. Reducing diagnostic time is critica…
View article: Consensus Guidelines for Evaluation and Management of Pulmonary Disease in Sjögren’s
Consensus Guidelines for Evaluation and Management of Pulmonary Disease in Sjögren’s Open
Clinical practice guidelines for pulmonary manifestations in Sjögren's will improve early identification, evaluation, and uniformity of care by primary care physicians, rheumatologists, and pulmonologists. Additionally, opportunities for f…
View article: Study of Hawaii Geothermal Opaline Silica Deposits with Raman, Luminescence, NIR Reflectance and X-Ray Diffraction Instruments
Study of Hawaii Geothermal Opaline Silica Deposits with Raman, Luminescence, NIR Reflectance and X-Ray Diffraction Instruments Open
Study of Hawaii Geothermal opaline silica deposits with
View article: Low hydroxychloroquine blood levels in patients who have had gastric bypass surgery
Low hydroxychloroquine blood levels in patients who have had gastric bypass surgery Open
Gastric bypass surgery, also called Roux-en-Y gastric bypass (RYGB), can result in the malabsorption of medications, requiring the use of higher than usual doses in order to achieve a therapeutic effect. We describe the results of hydroxyc…
View article: 183 A phase 1B/2A trial of tofacitinib, an oral janus kinase inhibitor, in systemic lupus erythematosus
183 A phase 1B/2A trial of tofacitinib, an oral janus kinase inhibitor, in systemic lupus erythematosus Open
Background A pharmacologic intervention that modulates JAK/STAT signaling pathways represents a novel approach for the treatment of Systemic Lupus Erythematosus (SLE). In animal models of SLE, tofacitinib improved clinical features, immune…
View article: Hawaii Play Fairway: Preliminary Core Box Photos, Lanai Island, Hawaii
Hawaii Play Fairway: Preliminary Core Box Photos, Lanai Island, Hawaii Open
Photos of core samples from Lanai Island. During the third phase of the Hawaii Play Fairway project, further exploration involved drilling a groundwater well in Lanai's Palawai Basin and performing more geophysical surveys. The project dee…
View article: Stacking Tetraurea Macrocycles as Self-Assembled Chloride Receptors in Aqueous Solutions
Stacking Tetraurea Macrocycles as Self-Assembled Chloride Receptors in Aqueous Solutions Open
Artificial receptors that recognise anionic species via noncovalent interactions have a wide range of biomedical, industrial and environmental applications. A major challenge in this area of research is to achieve high affinity and selecti…
View article: Tetraurea macrocycles: aggregation-driven binding of chloride in aqueous solutions
Tetraurea macrocycles: aggregation-driven binding of chloride in aqueous solutions Open
Artificial receptors that recognise anionic species vianoncovalent interactions have a wide range of biomedical, industrial and environmental applications. A major challenge in this area of research is to achieve high affinity and selectiv…
View article: Keynote speaker moving digital system design courses into the modern era, again
Keynote speaker moving digital system design courses into the modern era, again Open
After 50+ years of digital system design being a course topic in Electrical Engineering Departments, the complexity of basic digital systems has risen greatly. Many so-called fundamental topics have fallen by the wayside as being irrelevan…