Donald Hansom
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View article: Antifungal-Loaded Calcium Sulfate Beads as a Potential Therapeutic in Combating Candida auris
Antifungal-Loaded Calcium Sulfate Beads as a Potential Therapeutic in Combating Candida auris Open
Candida auris provides a substantial global nosocomial threat clinically. With the recent emergence that the organism can readily colonize skin niches, it will likely continue to pose a risk in health care units, particularly to patients u…
View article: Assessing the Bioactive Profile of Antifungal-Loaded Calcium Sulfate against Fungal Biofilms
Assessing the Bioactive Profile of Antifungal-Loaded Calcium Sulfate against Fungal Biofilms Open
Calcium sulfate (CS) has been used clinically as a bone- or void-filling biomaterial, and its resorptive properties have provided the prospect for its use as a release mechanism for local antibiotics to control biofilms. Here, we aimed to …
View article: Current evidence around patellar tendon graft in ACLR for high-risk patients: current concepts
Current evidence around patellar tendon graft in ACLR for high-risk patients: current concepts Open
Hamstrings and patellar tendon (PT) are the most common autografts used to perform anterior cruciate ligament (ACL) reconstructions. The debate to know which graft should be better has been going on for decades. However, in relation to und…
View article: Implications of Antimicrobial Combinations in Complex Wound Biofilms Containing Fungi
Implications of Antimicrobial Combinations in Complex Wound Biofilms Containing Fungi Open
Diabetic foot ulcer treatment currently focuses on targeting bacterial biofilms, while dismissing fungi. To investigate this, we used an in vitro biofilm model containing bacteria and fungi, reflective of the wound environment, to test the…
View article: Development and characterisation of a novel three-dimensional inter-kingdom wound biofilm model
Development and characterisation of a novel three-dimensional inter-kingdom wound biofilm model Open
Chronic diabetic foot ulcers are frequently colonised and infected by polymicrobial biofilms that ultimately prevent healing. This study aimed to create a novel in vitro inter-kingdom wound biofilm model on complex hydrogel-based cellulose…