D Santoro
YOU?
Author Swipe
View article: Early Response to Sibutramine in Patients Not Meeting Current Label Criteria: Preliminary Analysis of SCOUT Lead‐in Period
Early Response to Sibutramine in Patients Not Meeting Current Label Criteria: Preliminary Analysis of SCOUT Lead‐in Period Open
The Sibutramine Cardiovascular Outcomes (SCOUT) trial protocol defines a patient population predominantly outside current European Union label criteria. This article explores responses to sibutramine during the 6‐week, single‐blind, lead‐i…
View article: Insulin resistance and vasodilation in essential hypertension. Studies with adenosine.
Insulin resistance and vasodilation in essential hypertension. Studies with adenosine. Open
Insulin-mediated vasodilation has been proposed as a determinant of in vivo insulin sensitivity. We tested whether sustained vasodilation with adenosine could overcome the muscle insulin resistance present in mildly overweight patients wit…
View article: Impaired insulin action on skeletal muscle metabolism in essential hypertension.
Impaired insulin action on skeletal muscle metabolism in essential hypertension. Open
Previous studies have shown that essential hypertension is frequently associated with insulin resistance. The tissues responsible for this metabolic alteration have not been defined. We tested the hypothesis that skeletal muscle is the sit…
View article: Direct evidence for a stimulatory effect of hyperglycemia per se on peripheral glucose disposal in type II diabetes.
Direct evidence for a stimulatory effect of hyperglycemia per se on peripheral glucose disposal in type II diabetes. Open
The effect of hyperglycemia per se on glucose uptake by muscle tissue was quantitated in six controls and six type II diabetics by the forearm technique, under conditions of insulin deficiency induced by somatostatin (SRIF) infusion (0.7 m…