Dong Liu
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View article: Flow cytometry-based validation of soluble biomarker detection
Flow cytometry-based validation of soluble biomarker detection Open
View article: Engineering high-performance flexible symmetric microsupercapacitors boosted by tip-electric-field effect for integrated circuits
Engineering high-performance flexible symmetric microsupercapacitors boosted by tip-electric-field effect for integrated circuits Open
View article: Correlation Between Hemodynamic Characterizations of Cervical Arteries and Changes in Cerebral Microcirculation Under Dobutamine Stress: A Self- Controlled Study
Correlation Between Hemodynamic Characterizations of Cervical Arteries and Changes in Cerebral Microcirculation Under Dobutamine Stress: A Self- Controlled Study Open
Background Dobutamine, an inotropic agent, is known to enhance cardiac function. However, its concurrent effects on cervical artery hemodynamics and cerebral microcirculation, along with their potential correlation, remain unclear. This st…
View article: Differentiating Tumor Recurrence and Pseudoprogression in Postoperative Gliomas Using Pseudo- continuous Arterial Spin Labeling (pCASL) Technique
Differentiating Tumor Recurrence and Pseudoprogression in Postoperative Gliomas Using Pseudo- continuous Arterial Spin Labeling (pCASL) Technique Open
Objective: To assess whether the pCASL technique and its radiomics features can enhance the differentiation between tumor recurrence (TR) and pseudoprogression (PsP) in postoperative glioma patients. Methods: A retrospective study of 120 p…
View article: Lateral patellar retinaculum hypertrophy on magnetic resonance imaging predicts patellar subluxation in femoral trochlear dysplasia
Lateral patellar retinaculum hypertrophy on magnetic resonance imaging predicts patellar subluxation in femoral trochlear dysplasia Open
Purpose To explore the magnetic resonance imaging (MRI) features of the medial patellofemoral ligament (MPFL) and lateral patellar retinaculum (LPR) in femoral trochlear dysplasia (FTD) and assess their utility in predicting patellar sublu…
View article: A novel abdominal wall retractor to complete laparoscopic intracorporeal circular-stapled esophagojejunostomy after radical gastric cancer surgery—a single-center clinical study
A novel abdominal wall retractor to complete laparoscopic intracorporeal circular-stapled esophagojejunostomy after radical gastric cancer surgery—a single-center clinical study Open
BackgroundExploring effective, safe, and minimally traumatic anastomosis methods after total gastrectomy has been a key research focus, particularly for esophagojejunal anastomosis. Laparoscopic circular stapling is a novel technique for e…
View article: BlueLM-2.5-3B Technical Report
BlueLM-2.5-3B Technical Report Open
We present BlueLM-2.5-3B, a compact and unified dense Multimodal Large Language Model (MLLM) designed for efficient edge-device deployment, offering strong general-purpose and reasoning capabilities. To the best of our knowledge, this is t…
View article: Determination of Main Bearing Dynamic Clearance in a Shield Tunneling Machine Through a Broadband PMUT Array with a Decreased Blind Area and High Accuracy
Determination of Main Bearing Dynamic Clearance in a Shield Tunneling Machine Through a Broadband PMUT Array with a Decreased Blind Area and High Accuracy Open
Traditional PMUT ultrasonic ranging systems usually possess a large measurement blind area under the integrated transmit–receive mode, dramatically limiting its distance measurement in confined spaces, such as when determining the clearanc…
View article: A rare case of multiple gastric duplication cysts in an adult
A rare case of multiple gastric duplication cysts in an adult Open
View article: Targeting neuroinflammation: 3-monothiopomalidomide a new drug candidate to mitigate traumatic brain injury and neurodegeneration
Targeting neuroinflammation: 3-monothiopomalidomide a new drug candidate to mitigate traumatic brain injury and neurodegeneration Open
View article: Cryptogenic organizing pneumonia complicated by pulmonary embolism following glucocorticoid therapy: a case report
Cryptogenic organizing pneumonia complicated by pulmonary embolism following glucocorticoid therapy: a case report Open
Clinicians should consider COP in elderly patients with pneumonia unresponsive to antibiotics, confirm the diagnosis through biopsy, and remain vigilant for hypercoagulable states during glucocorticoid tapering. Anticoagulation should be t…
View article: The Advantages and Safety of Ultrasound-Guided Infusion Port Implantation via Axillary Vein
The Advantages and Safety of Ultrasound-Guided Infusion Port Implantation via Axillary Vein Open
View article: Low-grade appendiceal mucinous neoplasm at appendiceal orifice treated <i>via</i> appendectomy with double purse-string suture method: A case report
Low-grade appendiceal mucinous neoplasm at appendiceal orifice treated <i>via</i> appendectomy with double purse-string suture method: A case report Open
BACKGROUND Low-grade appendiceal mucinous neoplasms (LAMNs) are a class of histologically well-differentiated adenomas that can proliferate outside the appendix in the form of malignant tumours, resulting in the accumulation of external ap…
View article: Pharmacokinetics and Safety Evaluation of a New Generic Sitafloxacin: A Phase I Bioequivalence Study in Healthy Chinese Participants
Pharmacokinetics and Safety Evaluation of a New Generic Sitafloxacin: A Phase I Bioequivalence Study in Healthy Chinese Participants Open
Sitafloxacin is a new antibiotic drug belonging to the fourth generation quinolone antibiotics. The aim of this study was to evaluate the pharmacokinetics (PK), safety profiles, and bioequivalence of test and reference 50‐mg sitafloxacin t…
View article: A comprehensive analysis of deubiquitinase <scp>USP20</scp> on prognosis and immunity in pan‐cancer
A comprehensive analysis of deubiquitinase <span>USP20</span> on prognosis and immunity in pan‐cancer Open
USP20 is a deubiquitinase enzyme in the ubiquitin–proteasome system that plays a role in the development and progression of tumors. However, the relationships between USP20 expression and clinical prognosis and tumor immunity remain unclea…
View article: Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and <i>Lactobacillus amylovorus</i>
Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and <i>Lactobacillus amylovorus</i> Open
Baicalin has been widely used for its anti‐inflammatory pharmacological properties, yet its effects on bacterial intestinal inflammation and the mechanisms remain unclear. This study revealed that baicalin alleviates bacterial intestinal i…
View article: Bioengineered Versatile Heterojunctions as Stress Busters Targeting Matrix Degradation and Ferroptosis for Osteoarthritis Therapy (Adv. Funct. Mater. 16/2025)
Bioengineered Versatile Heterojunctions as Stress Busters Targeting Matrix Degradation and Ferroptosis for Osteoarthritis Therapy (Adv. Funct. Mater. 16/2025) Open
View article: Hemagglutinin with a polybasic cleavage site confers high virulence on H7N9 avian influenza viruses
Hemagglutinin with a polybasic cleavage site confers high virulence on H7N9 avian influenza viruses Open
H7N9 avian influenza virus (AIV) first emerged in February 2013 in China, and early isolates were all low pathogenic (LP). After circulation for a few years in live poultry markets of China, LP H7N9 AIVs evolved into a highly pathogenic (H…
View article: Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders: Present trends and future directions
Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders: Present trends and future directions Open
BACKGROUND Bipolar disorder (BD) is a severe mental illness characterized by significant mood swings. Effective drug treatment modalities are crucial for managing BD. AIM To analyze the current status and future trends of global research o…
View article: Regional homogeneity patterns reveal the genetic and neurobiological basis of State-Trait Anxiety
Regional homogeneity patterns reveal the genetic and neurobiological basis of State-Trait Anxiety Open
The ReHo patterns associated with anxiety may be driven by genetic and neurobiological traits. Our findings contribute to a deeper understanding of the pathogenesis of anxiety from a genetic and molecular perspective.
View article: Anisodamine (654-1/654-2) ameliorates septic kidney injury in rats by inhibiting inflammation and apoptosis
Anisodamine (654-1/654-2) ameliorates septic kidney injury in rats by inhibiting inflammation and apoptosis Open
Introduction To investigate the protective effects of anisodamine (654-1/654-2) against acute kidney injury (AKI) in LPS-induced septic shock rats and explore its molecular mechanisms. Methods 56 rats were randomly divided into 8 groups: c…
View article: Prevalence and Trends of Transfusion-Transmissible HBV Infection Among Blood Donors in Southwestern China: A Six-Year Retrospective Study
Prevalence and Trends of Transfusion-Transmissible HBV Infection Among Blood Donors in Southwestern China: A Six-Year Retrospective Study Open
Our findings indicate a decreasing trend in HBV prevalence among blood donors in Southwestern China over the 6-year study period. This decline may be attributed to the widespread administration of HBV vaccinations and stringent screening m…
View article: Evaluation of Population Pharmacokinetic Models of Micafungin: Implications for Dosing Regimen Optimization in Critically Ill Patients
Evaluation of Population Pharmacokinetic Models of Micafungin: Implications for Dosing Regimen Optimization in Critically Ill Patients Open
Micafungin (MFG) is a widely used echinocandin antifungal agent for treating invasive candidiasis, particularly in critically ill patients. However, its pharmacokinetics can be highly variable in this population. This systematic review aim…
View article: Huaier relieves oxaliplatin-induced hepatotoxicity through activation of the PI3K/AKT/Nrf2 signaling pathway in C57BL/6 mice
Huaier relieves oxaliplatin-induced hepatotoxicity through activation of the PI3K/AKT/Nrf2 signaling pathway in C57BL/6 mice Open
View article: Development and validation of a risk score nomogram model to predict the risk of 5-year all-cause mortality in diabetic patients with hypertension: A study based on NHANES data
Development and validation of a risk score nomogram model to predict the risk of 5-year all-cause mortality in diabetic patients with hypertension: A study based on NHANES data Open
View article: Editorial Expression of Concern: Activated protein C inhibits tissue plasminogen activator–induced brain hemorrhage
Editorial Expression of Concern: Activated protein C inhibits tissue plasminogen activator–induced brain hemorrhage Open
View article: Retraction Note: Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C
Retraction Note: Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C Open
View article: supporting data
supporting data Open
the supporting data is original data for the manuscript
View article: Diffusion along the perivascular space as a potential biomarker for glioma grading and isocitrate dehydrogenase 1 mutation status prediction
Diffusion along the perivascular space as a potential biomarker for glioma grading and isocitrate dehydrogenase 1 mutation status prediction Open
The reduced ALPS-index may reflect tumor-induced glymphatic system impairment, and the ALPS-index may be able to complement conventional diffusion metrics in glioma grading and IDH1 genotyping.
View article: Development and validation of enzyme-linked immunosorbent assays for the measurement of infliximab and anti-drug antibody levels
Development and validation of enzyme-linked immunosorbent assays for the measurement of infliximab and anti-drug antibody levels Open
Infliximab and its anti-drug antibody (ADA) serum concentrations exhibit a strong correlation with clinical response and loss of response. The use of therapeutic drug monitoring to measure the concentration of infliximab and ADA can…