Dazhi Yin
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View article: Time-dependent consolidation mechanisms of durable memory in spaced learning
Time-dependent consolidation mechanisms of durable memory in spaced learning Open
Emerging studies suggest that time-dependent consolidation enables memory stabilization by promoting memory integration and hippocampal-cortical transfer. Compared to massed learning, how time-dependent consolidation contributes to forming…
View article: Exploring the transmission of cognitive task information through optimal brain pathways
Exploring the transmission of cognitive task information through optimal brain pathways Open
Understanding the large-scale information processing that underlies complex human cognition is the central goal of cognitive neuroscience. While emerging activity flow models demonstrate that cognitive task information is transferred by in…
View article: Common and unique network basis for externally and internally driven flexibility in cognition: From a developmental perspective
Common and unique network basis for externally and internally driven flexibility in cognition: From a developmental perspective Open
Flexibility is a hallmark of cognitive control and can be driven externally and internally, corresponding to reactive and spontaneous flexibility. However, the convergence and divergence between these two types of flexibility and their und…
View article: Activity flow under the manipulation of cognitive load and training
Activity flow under the manipulation of cognitive load and training Open
Flexible cognitive functions, such as working memory (WM), usually require a balance between localized and distributed information processing. However, it is challenging to uncover how local and distributed processing specifically contribu…
View article: Dynamic changes on brain function during early stage of Tai Chi training: A motor imagery-based fMRI study
Dynamic changes on brain function during early stage of Tai Chi training: A motor imagery-based fMRI study Open
View article: Pathway-Specific Mediation Effect Between Structure, Function, and Motor Impairment After Subcortical Stroke
Pathway-Specific Mediation Effect Between Structure, Function, and Motor Impairment After Subcortical Stroke Open
This study reveals causal influence of structural and functional pathways on motor impairment after subcortical stroke and provides a promising way to investigate pathway-specific structure-function coupling. Clinically, our findings may o…
View article: Activity flow mapping over probabilistic functional connectivity
Activity flow mapping over probabilistic functional connectivity Open
Emerging evidence indicates that activity flow over resting‐state network topology allows the prediction of task activations. However, previous studies have mainly adopted static, linear functional connectivity (FC) estimates as activity f…
View article: Partial event coincidence analysis for distinguishing direct and indirect coupling in functional network construction
Partial event coincidence analysis for distinguishing direct and indirect coupling in functional network construction Open
Correctly identifying interaction patterns from multivariate time series presents an important step in functional network construction. In this context, the widespread use of bivariate statistical association measures often results in a fa…
View article: Cognitive Dysfunction in Type 2 Diabetes Is Not a One-Way Process: Evidence From a Longitudinal Brain Connectivity Study
Cognitive Dysfunction in Type 2 Diabetes Is Not a One-Way Process: Evidence From a Longitudinal Brain Connectivity Study Open
Background Cognitive dysfunction is an important comorbidity of diabetes characterized by brain functional hypo-connectivity. However, our recent study demonstrated an adaptive hyper-connectivity in young type 2 diabetes with cognitive dec…
View article: Common and Distinct Disruptions of Cortical Surface Morphology Between Autism Spectrum Disorder Children With and Without SHANK3 Deficiency
Common and Distinct Disruptions of Cortical Surface Morphology Between Autism Spectrum Disorder Children With and Without SHANK3 Deficiency Open
SH3 and Multiple Ankyrin Repeat Domains 3 ( SHANK3 )-caused autism spectrum disorder (ASD) may present a unique opportunity to clarify the heterogeneous neuropathological mechanisms of ASD. However, the specificity and commonality of disru…
View article: Understanding neural flexibility from a multifaceted definition
Understanding neural flexibility from a multifaceted definition Open
Flexibility is a hallmark of human intelligence. Emerging studies have proposed several flexibility measurements at the level of individual regions, to produce a brain map of neural flexibility. However, flexibility is usually inferred fro…
View article: A graph representation of functional diversity of brain regions
A graph representation of functional diversity of brain regions Open
Introduction Modern network science techniques are popularly used to characterize the functional organization of the brain. A major challenge in network neuroscience is to understand how functional characteristics and topological architect…
View article: Compensatory Hippocampal Connectivity in Young Adults With Early-Stage Type 2 Diabetes
Compensatory Hippocampal Connectivity in Young Adults With Early-Stage Type 2 Diabetes Open
Our findings suggest an adaptive compensation of brain function to counteract the insidious cognitive decrements during the early stage of T2DM. Additionally, the functional alterations occurring before changes in brain structure and perip…
View article: Brain Map of Intrinsic Functional Flexibility in Anesthetized Monkeys and Awake Humans
Brain Map of Intrinsic Functional Flexibility in Anesthetized Monkeys and Awake Humans Open
Emerging neuroimaging studies emphasize the dynamic organization of spontaneous brain activity in both human and non-human primates, even under anesthesia. In a recent study, we were able to characterize the heterogeneous architecture of i…
View article: Dual integrin αvβ 3 and NRP-1-Targeting Paramagnetic Liposome for Tumor Early Detection in Magnetic Resonance Imaging
Dual integrin αvβ 3 and NRP-1-Targeting Paramagnetic Liposome for Tumor Early Detection in Magnetic Resonance Imaging Open
Enhanced MRI (magnetic resonance imaging) plays a vital role in the early detection of tumor but with low specificity. Molecular imaging of angiogenesis could efficiently deliver contrast agents to the tumor site by specific targeted carri…
View article: Frequency‐specific alterations of regional homogeneity in subcortical stroke patients with different outcomes in hand function
Frequency‐specific alterations of regional homogeneity in subcortical stroke patients with different outcomes in hand function Open
Emerging evidence has suggested that abnormalities in regional spontaneous brain activity following stroke may be detected by intrinsic low‐frequency oscillations (LFO) in resting‐state functional MRI (R‐fMRI). However, the relationship be…
View article: Functional network changes in the hippocampus contribute to depressive symptoms in epilepsy
Functional network changes in the hippocampus contribute to depressive symptoms in epilepsy Open
View article: Altered intra‐ and inter‐network functional coupling of resting‐state networks associated with motor dysfunction in stroke
Altered intra‐ and inter‐network functional coupling of resting‐state networks associated with motor dysfunction in stroke Open
Motor functions are supported through functional integration across the extended motor system network. Individuals following stroke often show deficits on motor performance requiring coordination of multiple brain networks; however, the as…
View article: Brain anomaly networks uncover heterogeneous functional reorganization patterns after stroke
Brain anomaly networks uncover heterogeneous functional reorganization patterns after stroke Open
Stroke has a large physical, psychological, and financial burden on patients, their families, and society. Based on functional networks (FNs) constructed from resting state fMRI data, network connectivity after stroke is commonly conjectur…
View article: Failure in Cognitive Suppression of Negative Affect in Adolescents with Generalized Anxiety Disorder
Failure in Cognitive Suppression of Negative Affect in Adolescents with Generalized Anxiety Disorder Open
View article: Identification of the Genetic Cause for Childhood Disintegrative Disorder by Whole-Exome Sequencing
Identification of the Genetic Cause for Childhood Disintegrative Disorder by Whole-Exome Sequencing Open
View article: Altered Effective Connectivity of the Primary Motor Cortex in Stroke: A Resting-State fMRI Study with Granger Causality Analysis
Altered Effective Connectivity of the Primary Motor Cortex in Stroke: A Resting-State fMRI Study with Granger Causality Analysis Open
The primary motor cortex (M1) is often abnormally recruited in stroke patients with motor disabilities. However, little is known about the alterations in the causal connectivity of M1 following stroke. The purpose of the present study was …
View article: Dissociable Changes of Frontal and Parietal Cortices in Inherent Functional Flexibility across the Human Life Span
Dissociable Changes of Frontal and Parietal Cortices in Inherent Functional Flexibility across the Human Life Span Open
Extensive evidence suggests that frontoparietal regions can dynamically update their pattern of functional connectivity, supporting cognitive control and adaptive implementation of task demands. However, it is largely unknown whether this …
View article: Abnormal Functional Connectivity of the Amygdala-Based Network in Resting-State fMRI in Adolescents with Generalized Anxiety Disorder
Abnormal Functional Connectivity of the Amygdala-Based Network in Resting-State fMRI in Adolescents with Generalized Anxiety Disorder Open
Adolescents with GAD have abnormalities in brain regions associated with the emotional processing pathways.