Explanipedia

CALR accelerates the growth of liver cancer cells by enhancing telomere activity via ARAF Open

Sijie Xie, Xiaoxue Jiang, Xinlei Liu, Shuting Song, Liyan Wang , et al. · 2025

circ-miR-524 accelerates the growth of liver cancer cells by inducing DNA damage repair through K-RAS Open

Yanan Lu, Dongdong Lu · 2025

CARM1 accelerates the growth of liver cancer cells by enhancing ARAF Open

Xiaoxue Jiang, Libo Xing, Yi Lü, Rushi Qin, Liyan Wang , et al. · 2024

miR-933 accelerates the growth of liver cancer cells by enhancing pyruvate kinase isoform M2 Open

Liyan Wang, Shujie Li, Xinlei Liu, Sijie Xie, Shuting Song , et al. · 2023

miR-3200 accelerates the growth of liver cancer cells by enhancing Rab7A Open

Shuting Song, Sijie Xie, Xinlei Liu, Shujie Li, Liyan Wang , et al. · 2023

Researches indicate miR-3200 is closely related to tumorigenesis, However, the role of miR-3200 in human hepatocarcinogenesis is still unclear. In this study, we clearly demonstrate that miR-3200 accelerates the growth of liver cancer cell…

miR-624 accelerates the growth of liver cancer cells by inhibiting EMC3 Open

Xiaoxue Jiang, Yi Lü, Sijie Xie, Yingji Chen, Xinlei Liu , et al. · 2023

Retraction Notice to: SET1A Cooperates With CUDR to Promote Liver Cancer Growth and Hepatocyte-like Stem Cell Malignant Transformation Epigenetically Open

Tianming Li, Qidi Zheng, Jiahui An, Mengying Wu, Haiyan Li , et al. · 2023

A lncRNA MEG3 variant enhances telomerase activity by increasing DNA damage repair ability in human liver cancer stem cells Open

Yanan Lu, Shujie Li, Shuting Song, Liyan Wang, Yingjie Chen , et al. · 2022

Retraction Notice to: GLP2 Promotes Directed Differentiation from Osteosarcoma Cells to Osteoblasts and Inhibits Growth of Osteosarcoma Cells Open

Yi Lu, Dongdong Lu, Yu Hu · 2022

Retraction Notice to: Inflammatory-Related P62 Triggers Malignant Transformation of Mesenchymal Stem Cells through the Cascade of CUDR-CTCF-IGFII-RAS Signaling Open

Xiaoru Xin, Chen Wang, Zhuojia Lin, Jie Xu, Yanan Lu , et al. · 2022

miR-1307 promotes hepatocarcinogenesis by CALR-OSTC-endoplasmic reticulum protein folding pathway Open

Sijie Xie, Xiaoxue Jiang, Rushi Qin, Shuting Song, Yanan Lu , et al. · 2021

miR-1307 is highly expressed in liver cancer and inhibits methyltransferase protein8. Thereby, miR-1307 inhibits the expression of KDM3A and KDM3B and increases the methylation modification of histone H3 lysine 9, which enhances the expres…

Mutant MEG3 Enhances the Activity of Telomerase by Increasing DNA Damage Repair in Human Liver Cancer Stem Cells Open

Shuting Song, Sijie Xie, Rushi Qin, Yanan Lu, Liyan Wang , et al. · 2021

Background: Long noncoding RNAs have recently considered as central regulators in diverse biological processes and emerged as vital players controlling tumorigenesis. Although wild MEG3 acts as a suppressor in several cancers, the function…

MiR-26a-1 Promotes DNA Damage Repair by Inhibiting Sirt1 and KDM5A in Human Liver Cancer Stem Cells Open

Liyan Wang, Xiaonan Li, Rushi Qin, Yanan Lu, Shuting Song , et al. · 2021

Background: Although miR-26a-1 was down-regulated expressin in several cancers, the role of miR-26a-1in malignancies has yet to be systematically elucidated. Methods: RT-PCR, Western blotting and tumorigenesis test in vitro and in vivo wer…

Long noncoding RNA MEG3 blocks telomerase activity in human liver cancer stem cells epigenetically Open

Xiaoxue Jiang, Liyan Wang, Sijie Xie, Yingjie Chen, Shuting Song , et al. · 2020

CircMEG3 inhibits telomerase activity by reducing Cbf5 in human liver cancer stem cells Open

Xiaoxue Jiang, Libo Xing, Yingjie Chen, Rushi Qin, Shuting Song , et al. · 2020

Circular RNA (CircRNA) is a newly identified special class of non-coding RNA (ncRNA) that plays an important regulatory role in the progression of certain diseases. Herein, our results indicate that CircMEG3 is downregulated expression and…

Long noncoding RNA MEG3 blocks telomerase activity in human liver cancer stem cells epigenetically Open

Xiaoxue Jiang, Liyan Wang, Sijie Xie, Yingjie Chen, Shuting Song , et al. · 2020

Background: MEG3 is down-regulated expression in several tumors and inhibits human tumorigenesis. But so far, the mechanism of MEG3 in tumorigenesis is still unclear. Methods: Gene infection, cellular and molecular technologies and tumorig…

miR155 Enhances Autophagy by Reducing MBD5 and METTL3 in Human Liver Cancer Stem Cells Open

Yanan Lu, Ying‐Jie Chen, Xiaoru Xin, Shuting Song, Xiaoxue Jiang , et al. · 2020

Background: miR-155 is a widely reported carcinogenic miRNA, with up-regulated expression in a variety of human cancers. Methods: Liver cancer stem cells were isolated from Huh7 cells; gene infection, RT-PCR, Western blotting and tumorigen…

Long noncoding RNA MEG3 blocks telomerase activity in human liver cancer stem cells epigenetically Open

Xiaoxue Jiang, Liyan Wang, Sijie Xie, Yingjie Chen, Shuting Song , et al. · 2020

Background: MEG3 is abnormally down-regulated in most tumors and inhibits tumorigenesis. Methods: Gene infection, Western blotting and tumorigenesis test in vitro and in vivo were performed to analyze the signaling pathway. Results: MEG3 i…

Long noncoding RNA MEG3 blocks telomerase activity in human liver cancer stem cells epigenetically Open

Xiaoxue Jiang, Liyan wang, Sijie Xie, Yingjie Chen, Shuting Song , et al. · 2020

Background: MEG3 is abnormally down-regulated in most tumors and inhibits tumorigenesis. Methods: Gene infection, Western blotting and tumorigenesis test in vitro and in vivo were performed to analyze the signaling pathway. Results: MEG3 i…

miR-155 Accelerates the Growth of Human Liver Cancer Cells by Activating CDK2 via Targeting H3F3A Open

Xiaoru Xin, Yanan Lu, Sijie Xie, Ying‐Jie Chen, Xiaoxue Jiang , et al. · 2020

miR24‐2 accelerates progression of liver cancer cells by activating Pim1 through tri‐methylation of Histone H3 on the ninth lysine Open

Yuxin Yang, Shuting Song, Qiuyu Meng, Liyan Wang, Xiaonan Li , et al. · 2020

Several microRNAs are associated with carcinogenesis and tumour progression. Herein, our observations suggest both miR24‐2 and Pim1 are up‐regulated in human liver cancers, and miR24‐2 accelerates growth of liver cancer cells in vitro and …

Long noncoding RNA HULC accelerates the growth of human liver cancer stem cells by upregulating CyclinD1 through miR675-PKM2 pathway via autophagy Open

Chen Wang, Xiaoxue Jiang, Xiaonan Li, Shuting Song, Qiuyu Meng , et al. · 2020

Background The functions of HULC have been demonstrated in several cancers. However, its mechanism has not been elucidated in human liver cancer stem cells. Methods Liver cancer stem cells were isolated from Huh7 cells; gene infection and …

miR24-2 Promotes Malignant Progression of Human Liver Cancer Stem Cells by Enhancing Tyrosine Kinase Src Epigenetically Open

Liyan Wang, Xiaonan Li, Wei Zhang, Yuxin Yang, Qiuyu Meng , et al. · 2019

Long Noncoding RNA MEG3 Suppresses Liver Cancer Stem Cells Progression Through Inhibiting Telomerase Activity Open

Xiaonan Li, Xiaoxue Jiang, Qidi Zheng, Shuting Song, Liyan Wang , et al. · 2019

miR675 Accelerates Malignant Transformation of Mesenchymal Stem Cells by Blocking DNA Mismatch Repair Open

Yanan Lu, Shuting Song, Xiaoxue Jiang, Qiuyu Meng, Chen Wang , et al. · 2018

Long noncoding RNA HULC accelerates liver cancer by inhibiting PTEN via autophagy cooperation to miR15a Open

Xiaoru Xin, Mengying Wu, Qiuyu Meng, Chen Wang, Yanan Lu , et al. · 2018

miR372 Promotes Progression of Liver Cancer Cells by Upregulating erbB-2 through Enhancement of YB-1 Open

Zhuojia Lin, Yanan Lu, Qiuyu Meng, Chen Wang, Xiaonan Li , et al. · 2018

Inflammatory factor receptor Toll‐like receptor 4 controls telomeres through heterochromatin protein 1 isoforms in liver cancer stem cell Open

Qidi Zheng, Jie Xu, Zhuojia Lin, Yanan Lu, Xiaoru Xin , et al. · 2018

Toll‐like receptor 4 ( TLR 4) which acts as a receptor for lipopolysaccharide ( LPS ) has been reported to be involved in carcinogenesis. However, the regulatory mechanism of it has not been elucidated. Herein, we demonstrate that TLR 4 pr…

RETRACTED: Inflammatory-Related P62 Triggers Malignant Transformation of Mesenchymal Stem Cells through the Cascade of CUDR-CTCF-IGFII-RAS Signaling Open

Xiaoru Xin, Chen Wang, Zhuojia Lin, Jie Xu, Yanan Lu , et al. · 2018

Glucagon‐like peptide 2 decreases osteoclasts by stimulating apoptosis dependent on nitric oxide synthase Open

Yi Lu, Dongdong Lu, Yu Hu · 2018

Objectives Glucagon‐like peptide 2 ( GLP 2) is involved in the regulation of energy absorption and metabolism. Despite the importance of the GLP 2 signalling mechanisms on osteoclast, little has been studied on how GLP 2 works during osteo…

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