Dongna Zhang
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View article: Multi-timescale resilience of China's green finance market to climate policy uncertainty shock: Does environmental policy stringency matter?
Multi-timescale resilience of China's green finance market to climate policy uncertainty shock: Does environmental policy stringency matter? Open
This paper studies the resilience of China's green finance market to Chinese Climate Policy Uncertainty (CCPU) shock across multiple time scales. Resilience is measured using the Intensity Resilience of Risk Absorption (IRRA) and Duration …
View article: Antibacterial activity and mechanism of naphthoquine phosphate against ceftazidime-resistant Acinetobacter baumannii via cell membrane disruption and ROS induction
Antibacterial activity and mechanism of naphthoquine phosphate against ceftazidime-resistant Acinetobacter baumannii via cell membrane disruption and ROS induction Open
Introduction Drug-resistant bacteria, particularly Acinetobacter baumannii , present a significant threat to global public health, highlighting the urgent need for novel antibacterial therapies. Drug repurposing has emerged as a promising …
View article: Financial Deepening, Financial Inclusion, and Agricultural Investment: Evidence from International Panel Data
Financial Deepening, Financial Inclusion, and Agricultural Investment: Evidence from International Panel Data Open
View article: Recent advances in the treatment of non-small cell lung cancer with MET inhibitors
Recent advances in the treatment of non-small cell lung cancer with MET inhibitors Open
Recently, research into the oncogenic driver genes associated with non-small cell lung cancer (NSCLC) has advanced significantly, leading to the development and clinical application of an increasing number of approved therapeutic agents. A…
View article: In-cell bioluminescence resonance energy transfer (BRET)-based assay uncovers ceritinib and CA-074 as SARS-CoV-2 papain-like protease inhibitors
In-cell bioluminescence resonance energy transfer (BRET)-based assay uncovers ceritinib and CA-074 as SARS-CoV-2 papain-like protease inhibitors Open
Papain-like protease (PLpro) is an attractive anti-coronavirus target. The development of PLpro inhibitors, however, is hampered by the limitations of the existing PLpro assay and the scarcity of validated active compounds. We developed a …
View article: Activated Carbon Based on Recycled Epoxy Boards and Their Adsorption toward Methyl Orange
Activated Carbon Based on Recycled Epoxy Boards and Their Adsorption toward Methyl Orange Open
With the swift progress of the electronics industry, discarded circuit boards have become an important source of non-degradable waste. In this work, discarded epoxy resin was collected as a precursor to prepare activated carbon (AC) throug…
View article: <i>In vitro</i> interaction of naphthoquine with ivermectin, atovaquone, curcumin, and ketotifen in the asexual blood stage of <i>Plasmodium falciparum</i> 3D7
<i>In vitro</i> interaction of naphthoquine with ivermectin, atovaquone, curcumin, and ketotifen in the asexual blood stage of <i>Plasmodium falciparum</i> 3D7 Open
Naphthoquine is a promising candidate for antimalarial combination therapy. Its combination with artemisinin has demonstrated excellent efficacy in clinical trials conducted across various malaria-endemic areas. A co-formulated combination…
View article: Disulfide-incorporated lipid prodrugs of cidofovir: Synthesis, antiviral activity, and release mechanism
Disulfide-incorporated lipid prodrugs of cidofovir: Synthesis, antiviral activity, and release mechanism Open
View article: Orthogonal dual reporter-based gain-of-signal assay for probing SARS-CoV-2 3CL protease activity in living cells: inhibitor identification and mutation investigation
Orthogonal dual reporter-based gain-of-signal assay for probing SARS-CoV-2 3CL protease activity in living cells: inhibitor identification and mutation investigation Open
ABSTRACTThe main protease (3-chymotrypsin-like protease, 3CLpro) of SARS-CoV-2 has become a focus of anti-coronavirus research. Despite efforts, drug development targeting 3CLpro has been hampered by limitations in the currently ava…
View article: Design, Synthesis, and Biological Evaluation of Benzimidazole Derivatives as Potential Lassa Virus Inhibitors
Design, Synthesis, and Biological Evaluation of Benzimidazole Derivatives as Potential Lassa Virus Inhibitors Open
The Lassa virus (LASV) causes Lassa fever, a highly infectious and lethal agent of acute viral hemorrhagic fever. At present, there are still no effective treatments available, creating an urgent need to develop novel therapeutics. Some be…
View article: Orthogonal dual reporter-based gain-of-signal assay for probing SARS-CoV-2 3CL protease activity in living cells: inhibitor identification and mutation investigation
Orthogonal dual reporter-based gain-of-signal assay for probing SARS-CoV-2 3CL protease activity in living cells: inhibitor identification and mutation investigation Open
The main protease (3-chymotrypsin-like protease, 3CLpro) of SARS-CoV-2 has become a focus of anti-coronavirus research. Despite efforts, drug development targeting 3CLpro has been hampered by limitations in the currently available activity…
View article: Spray-Dried Inhalable Powder Formulations of Gentamicin Designed for Pneumonic Plague Therapy in a Mouse Model
Spray-Dried Inhalable Powder Formulations of Gentamicin Designed for Pneumonic Plague Therapy in a Mouse Model Open
Infection with Yersinia pestis (Y. pestis) may cause pneumonic plague, which is inevitably fatal without treatment. Gentamicin (GM), an aminoglycoside antibiotic, is a drug commonly used in the treatment of plague. However, it requires rep…
View article: Testing the Club Convergence Dynamics of the COVID-19 Vaccination Rates Across the OECD Countries
Testing the Club Convergence Dynamics of the COVID-19 Vaccination Rates Across the OECD Countries Open
Vaccines are essential to create a more resilient economic growth model. Ending the COVID-19 pandemic requires a more coordinated, effective, and equitable distribution of vaccines across the countries. Therefore, governments are in a race…
View article: Macroeconomic outcomes of OPEC and non-OPEC oil supply shocks in the euro area
Macroeconomic outcomes of OPEC and non-OPEC oil supply shocks in the euro area Open
View article: Naphthoquine: A Potent Broad-Spectrum Anti-Coronavirus Drug In Vitro
Naphthoquine: A Potent Broad-Spectrum Anti-Coronavirus Drug In Vitro Open
COVID-19 has spread around the world and caused serious public health and social problems. Although several vaccines have been authorized for emergency use, new effective antiviral drugs are still needed. Some repurposed drugs including Ch…
View article: Implications of Cryptocurrency Energy Usage on Climate Change
Implications of Cryptocurrency Energy Usage on Climate Change Open
View article: Clinical efficacy and safety evaluation of favipiravir in treating patients with severe fever with thrombocytopenia syndrome
Clinical efficacy and safety evaluation of favipiravir in treating patients with severe fever with thrombocytopenia syndrome Open
View article: Clinical effect and antiviral mechanism of T-705 in treating severe fever with thrombocytopenia syndrome
Clinical effect and antiviral mechanism of T-705 in treating severe fever with thrombocytopenia syndrome Open
View article: Convenient one-step synthesis of alkoxy substituted pyrazine derivatives
Convenient one-step synthesis of alkoxy substituted pyrazine derivatives Open
We report a one-step method for the synthesis of alkoxy substituted pyrazine derivatives. The process makes use of an improved acid-mediated coupling reaction to afford the products in good yields (70–90%). This method expands the scope to…
View article: Intangibles and the UK under-investment puzzle: Evidence from firm-level panel data
Intangibles and the UK under-investment puzzle: Evidence from firm-level panel data Open
View article: Sea surface current response patterns to tropical cyclones
Sea surface current response patterns to tropical cyclones Open
Tropical cyclones (TCs) are strong synoptic systems which induce strong sea surface currents. This paper first cross-checks a detailed surface current response to specific TCs Rammasun (2014), Kalmaegi (2014) and Sarika (2016) based on buo…
View article: Changes in Tropical-Cyclone Translation Speed over the Western North Pacific
Changes in Tropical-Cyclone Translation Speed over the Western North Pacific Open
The trend of tropical-cyclone (TC) translation speed is a hot topic recently. Changes in TC translation speed during 1949–2017 over the western North Pacific are analyzed using two best-track datasets here. The TC translation speed decreas…
View article: Transcription Factor MafB Suppresses Type I Interferon Production by CD14+ Monocytes in Patients With Chronic Hepatitis C
Transcription Factor MafB Suppresses Type I Interferon Production by CD14+ Monocytes in Patients With Chronic Hepatitis C Open
Transcription factor MafB regulates differentiation and activity of monocytes/macrophage and is associated with the development of atherosclerosis and cancers. However, the role of MafB in modulation of CD14+ monocytes in chroni…
View article: Discussion on the Key Properties of Fiberglass Tubing Used in Oilfield
Discussion on the Key Properties of Fiberglass Tubing Used in Oilfield Open
CNPC implements the call of energy conservation and emission reduction, and promotes the application of new energy conservation and emission reduction technologies and new products to achieve production and reduce pollution. As China’s oil…
View article: Net Modulation Of Upper Ocean Thermal Structure By Typhoon Kalmaegi (2014)
Net Modulation Of Upper Ocean Thermal Structure By Typhoon Kalmaegi (2014) Open
Field data and model output associated with the manuscript entitled "Net Modulation of Upper Ocean Thermal Structure by Typhoon Kalmaegi (2014)"
View article: Net Modulation Of Upper Ocean Thermal Structure By Typhoon Kalmaegi (2014)
Net Modulation Of Upper Ocean Thermal Structure By Typhoon Kalmaegi (2014) Open
Field data and model output associated with the manuscript entitled "Net Modulation of Upper Ocean Thermal Structure by Typhoon Kalmaegi (2014)"
View article: Selective Method for the Determination of Manganese in End-fitting of Spoolable Reinforced Plastic Line Pipe for Petroleum Industries
Selective Method for the Determination of Manganese in End-fitting of Spoolable Reinforced Plastic Line Pipe for Petroleum Industries Open
The fact that spoolable reinforced plastic line pipe is more flexible and spoolable than steel, and is also much lighter, means that it can becarried and deployedfrom smaller vessels and managed more easily. It was well known that manganes…
View article: Viral polymerase inhibitors T-705 and T-1105 are potential inhibitors of Zika virus replication
Viral polymerase inhibitors T-705 and T-1105 are potential inhibitors of Zika virus replication Open
View article: Design and Implementation of intrusion detection punctual response system
Design and Implementation of intrusion detection punctual response system Open
With the rapid development of IT technology and Internet, Network security has become an unavoidable issue, the pure firewall strategy can't satisfy the need of safe and highly sensitive departments.The network defense must adopt a deep, v…