Duo Yang
YOU?
Author Swipe
View article: Lactate and gastric cancer immunotherapy from regulatory mechanisms to therapeutic strategies: a critical review
Lactate and gastric cancer immunotherapy from regulatory mechanisms to therapeutic strategies: a critical review Open
This review elucidates the dual roles and clinical value of lactate in gastric cancer as both an energy substrate and a signalling molecule within the tumour microenvironment and positions lactylation as a critical metabolic-epigenetic bri…
View article: B Lymphocytes and Hyperglycemia Synergistically Exacerbate Coronary In-Stent Restenosis
B Lymphocytes and Hyperglycemia Synergistically Exacerbate Coronary In-Stent Restenosis Open
View article: Comparison of triglyceride-glucose related indices in prediction of cardiometabolic disease incidence among US midlife women
Comparison of triglyceride-glucose related indices in prediction of cardiometabolic disease incidence among US midlife women Open
View article: Association between TyG-BMI and gout in US adults: evidence from NHANES 2007–2018
Association between TyG-BMI and gout in US adults: evidence from NHANES 2007–2018 Open
Insulin resistance (IR) and obesity represent two major factors closely associated with gout. Triglyceride-glucose body mass index (TyG-BMI), calculated from fasting triglyceride and fasting glucose, has recently been proposed as a surroga…
View article: Relationships Between Exercise Components and Social Anxiety Levels Among Chinese College Students
Relationships Between Exercise Components and Social Anxiety Levels Among Chinese College Students Open
Objective This study aimed to explore the relationships between various exercise components (frequency, intensity, duration) and social anxiety.Methods A sample of 844 college students in China participated in this study. The Physical Acti…
View article: Global Temporal Trends and Projections of Anxiety Disorders Prevalence Among the Older Adults: An Age-Period-Cohort Analysis Based on the GBD 2021
Global Temporal Trends and Projections of Anxiety Disorders Prevalence Among the Older Adults: An Age-Period-Cohort Analysis Based on the GBD 2021 Open
View article: Bi-Level Optimization of Integrated Energy Systems Considering Multi-Hydrogen Supply and Integrated Demand Response
Bi-Level Optimization of Integrated Energy Systems Considering Multi-Hydrogen Supply and Integrated Demand Response Open
View article: Emergence of mcr-4.3 genes in a novel Shewanella specie isolated from the Arctic environment
Emergence of mcr-4.3 genes in a novel Shewanella specie isolated from the Arctic environment Open
Mobile colistin resistance (mcr) genes are pivotal contributors to last-line of antimicrobial resistance in human infections. Shewanella, historically recognized as a natural environmental bacterium with metal reduction capabilities, recen…
View article: Detecting horizontal gene transfer with metagenomics co-barcoding sequencing
Detecting horizontal gene transfer with metagenomics co-barcoding sequencing Open
Horizontal gene transfer (HGT) is the process through which genetic information is transferred between different genomes and that played a crucial role in bacterial evolution. HGT can enable bacteria to rapidly acquire antibiotic resistanc…
View article: Non-targeted Metabolomics Analysis Reveals Distinct Metabolic Profiles Between Positive and Negative Emotional Tears of Humans: A Preliminary Study
Non-targeted Metabolomics Analysis Reveals Distinct Metabolic Profiles Between Positive and Negative Emotional Tears of Humans: A Preliminary Study Open
Background Basal, reflex, and emotional tears differ in chemical components. It is not yet known whether chemical differences exist in tears of different emotions. We investigated the biochemical basis of emotional tears by performing non-…
View article: Role of the <i>fsr</i> Quorum-Sensing System in Enterococcus faecalis Bloodstream Infection
Role of the <i>fsr</i> Quorum-Sensing System in Enterococcus faecalis Bloodstream Infection Open
First, we conducted an advanced study on the genomic differences between colonizing and infecting E. faecalis , which provides support and evidence for early and accurate diagnoses. Second, we discovered that fsr was significantly associat…
View article: Non-targeted metabolomics analysis reveals distinct metabolic profiles between positive and negative emotional tears of humans
Non-targeted metabolomics analysis reveals distinct metabolic profiles between positive and negative emotional tears of humans Open
BACKGROUND Although the chemical components of basal, reflex, and emotional tears are different, the presence of distinctions in the tears of different emotions is still unknown. The present study aimed to address the biochemical basis beh…
View article: The Hippo Signaling Pathway: The Trader of Tumor Microenvironment
The Hippo Signaling Pathway: The Trader of Tumor Microenvironment Open
The Hippo pathway regulates cancer biology in many aspects and the crosstalk with other pathways complicates its role. Accumulated evidence has shown that the bidirectional interactions between tumor cells and tumor microenvironment (TME) …
View article: Blood microbiota diversity determines response of advanced colorectal cancer to chemotherapy combined with adoptive T cell immunotherapy
Blood microbiota diversity determines response of advanced colorectal cancer to chemotherapy combined with adoptive T cell immunotherapy Open
Human microbiota influence the response of malignancies to treatment with immune checkpoint blockade; however, their impact on other forms of immunotherapy is poorly understood. This study explored the effect of blood microbiota on clinica…
View article: Clearance of Circulating Bacteria and Recovery of Microbiota Diversity Following Adoptive Cellular Therapy in Advanced Colorectal Cancer Patients
Clearance of Circulating Bacteria and Recovery of Microbiota Diversity Following Adoptive Cellular Therapy in Advanced Colorectal Cancer Patients Open
Objective: There is increasing evidence of a human blood-microbiome that may have an immune modulatory effect. Anticancer therapies including adoptive cellular therapy (ACT) may influence this blood microbiome. The purpose of this study wa…
View article: [Outcomes of 138 myelodysplastic syndrome patients with HLA-matched sibling donor allogeneic hematopoietic stem cell transplantation].
[Outcomes of 138 myelodysplastic syndrome patients with HLA-matched sibling donor allogeneic hematopoietic stem cell transplantation]. Open
Objective: To evaluate the outcomes of myelodysplastic syndromes (MDS) patients who received HLA-matched sibling donor allogeneic peripheral blood stem cell transplantation (MSD-PBSCT) . Methods: The clinical data of 138 MDS …
View article: [Outcomes and prognostic factors of myelodysplastic syndrome patients with allogeneic hematopoietic stem cell transplantation].
[Outcomes and prognostic factors of myelodysplastic syndrome patients with allogeneic hematopoietic stem cell transplantation]. Open
Objective: To evaluate the outcomes and prognostic factors of myelodysplasia syndrome (MDS) patients who received allogeneic hematopoietic stem cell transplantation (allo-HSCT) . Methods: 165 cases of MDS who underwent allo-H…
View article: [Decitabine-based conditioning regimen is feasible and effective in the treatment of myelodysplastic syndrome and chronic myelomonocytic leukemia].
[Decitabine-based conditioning regimen is feasible and effective in the treatment of myelodysplastic syndrome and chronic myelomonocytic leukemia]. Open
Objective: To assess the efficacy and toxicity of decitabine-based conditioning regimen in patients with myelodysplastic syndrome (MDS) , acute myeloid leukemia secondary to MDS (MDS-AML) or chronic myelomonocytic leukemia (CMML) . …
View article: Spontaneous adipogenic differentiation potential of adipose‑derived stem cells decreased with increasing cell passages
Spontaneous adipogenic differentiation potential of adipose‑derived stem cells decreased with increasing cell passages Open
Primary adipose-derived stem cells (ADSCs) are a mixture of cell types including preadipocytes having the ability to spontaneously differentiate into adipocytes. The aim of the present study was to compare the spontaneous adipogenic differ…
View article: [Improved outcome by optimized conditioning regimens with an increased dose of cyclophosphamide in allogeneic peripheral blood stem cell transplantation for severe aplastic anemia].
[Improved outcome by optimized conditioning regimens with an increased dose of cyclophosphamide in allogeneic peripheral blood stem cell transplantation for severe aplastic anemia]. Open
OBJECTIVE: To respectively analyze the impact of conditioning regimens with a dose-decreased cyclophosphamide (Cy) on the outcome in fully matched sibling donor (MSD) peripheral blood stem cell transplantation (PBSCT) for severe aplastic a…