Dong‐Soo Suh
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View article: Clinical Outcomes of Poly(ADP–Ribose) Polymerase Inhibitors as Maintenance Therapy in Patients with Ovarian Cancer in the Southeastern Region of Korea
Clinical Outcomes of Poly(ADP–Ribose) Polymerase Inhibitors as Maintenance Therapy in Patients with Ovarian Cancer in the Southeastern Region of Korea Open
Purpose: In this study, we aimed to retrospectively investigate the real-world clinical efficacy and adverse events of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibitors in real-world clinical practice among patients wit…
View article: TRIB2 Stimulates Cancer Stem-Like Properties through Activating the AKT-GSK3β-β-Catenin Signaling Axis
TRIB2 Stimulates Cancer Stem-Like Properties through Activating the AKT-GSK3β-β-Catenin Signaling Axis Open
Tribbles homolog 2 (TRIB2) is implicated in tumorigenesis and drug resistance in various types of cancers. However, the role of TRIB2 in the regulation of tumorigenesis and drug resistance of cancer stem cells (CSCs) is still elusive. In t…
View article: The association between expression of p53 and aggressiveness of serous adenocarcinoma of the uterine cervix
The association between expression of p53 and aggressiveness of serous adenocarcinoma of the uterine cervix Open
High p53 expression and advanced stage may be associated with poorer clinical outcomes in SACC, which suggest that immunohistochemistry may contribute to the prediction of prognosis.
View article: The Efficacy of Body Mass Index and Total Body Fat Percent in Diagnosis Obesity according to Menopausal Status
The Efficacy of Body Mass Index and Total Body Fat Percent in Diagnosis Obesity according to Menopausal Status Open
We proposed new BMI criteria for obesity by using TBF reference. With application of bioelectrical impedance analysis, the diagnosis of obesity using BMI criteria may differ between premenopausal and postmenopausal women.
View article: Risk factors related to the recurrence of endometrioma in patients with long-term postoperative medical therapy
Risk factors related to the recurrence of endometrioma in patients with long-term postoperative medical therapy Open
We found that patients with dysmenorrhea after surgery, and a younger age of the patient at the time of surgery were the highest risk factors associated with the recurrence of endometrioma, despite long-term postoperative medication.
View article: TRRAP stimulates the tumorigenic potential of ovarian cancer stem cells
TRRAP stimulates the tumorigenic potential of ovarian cancer stem cells Open
Ovarian cancer is the most fatal gynecological malignancy in women and identification of new therapeutic targets is essential for the continued development of therapy for ovarian cancer. TRRAP (transformation/transcription domain-associate…
View article: Role of autotaxin in cancer stem cells
Role of autotaxin in cancer stem cells Open
View article: Crucial role of HMGA1 in the self-renewal and drug resistance of ovarian cancer stem cells
Crucial role of HMGA1 in the self-renewal and drug resistance of ovarian cancer stem cells Open
View article: Hypoxia-NOTCH1-SOX2 signaling is important for maintaining cancer stem cells in ovarian cancer
Hypoxia-NOTCH1-SOX2 signaling is important for maintaining cancer stem cells in ovarian cancer Open
Hypoxia and NOTCH signaling have been reported to be associated with the self-renewal and drug resistance of cancer stem cells (CSCs). However, the molecular mechanisms by which hypoxia and NOTCH signaling stimulate the self-renewal and dr…
View article: FOXP1 functions as an oncogene in promoting cancer stem cell-like characteristics in ovarian cancer cells
FOXP1 functions as an oncogene in promoting cancer stem cell-like characteristics in ovarian cancer cells Open
Ovarian cancer has the highest mortality rate of all gynecological cancers with a high recurrence rate. It is important to understand the nature of recurring cancer cells to terminally eliminate ovarian cancer. The winged helix transcripti…