Explanipedia

<span>NUPR1</span> Promotes Radioresistance in Colorectal Cancer Cells by Inhibiting Ferroptosis Open

Yimin Fang, Haiyan Chen, Yun-Hua Liu, Kai Jiang, Yucheng Qian , et al. · 2025

Radioresistance is a major clinical challenge and the underlying mechanism has not been thoroughly elucidated. In this study, a radioresistant (RR) cell line is established to explore the transcriptomic signatures of radioresistance in col…

Plunger Pump Fault Diagnosis Method Based on Wavelet Convolution and Multi-Head Self-Attention Mechanism for Multi-Channel Feature Fusion Open

Pu Zhou, Z. Qian, Dongliang Fu, Yi Zhang · 2025

Correction: Reinforcement of the thermal stability and mechanical properties of low-density polyethylene/high-density polyethylene foam using a modified calcium sulfate whisker Open

Jie Xu, Jinfu Zhong, Dongliang Fu, Guangfu Li, Xiangdong Liu · 2025

Correction for ‘Reinforcement of the thermal stability and mechanical properties of low-density polyethylene/high-density polyethylene foam using a modified calcium sulfate whisker’ by Jie Xu et al. , New J. Chem. , 2023, 47 , 17701–17712,…

Unveiling hsa_circ_0007439: a novel suppressor of nasopharyngeal carcinoma via miR-556-5p/PTEN Axis Open

Min Li, Jing Yang, Wei Feng, Dongliang Fu, Yang Bai · 2024

Circ_0007439 mediates miR-556-5p/PTEN axis to inhibit NPC progression as an potential target for NPC therapy.

Development and verification of a combined immune- and cancer-associated fibroblast related prognostic signature for colon adenocarcinoma Open

Jingsun Wei, Xiaoxu Ge, Yucheng Qian, Kai Jiang, Xin Chen , et al. · 2024

Introduction To better understand the role of immune escape and cancer-associated fibroblasts (CAFs) in colon adenocarcinoma (COAD), an integrative analysis of the tumor microenvironment was performed using a set of 12 immune- and CAF-rela…

Rigosertib promotes anti-tumor immunity via autophagic degradation of PD-L1 in colorectal cancer cells Open

Xinyi Zhou, Dongliang Fu, Hang Yang, Chenqin Le, Yier Lu , et al. · 2023

Rigosertib (RGS) is a benzyl styryl sulfone which exhibits impressive cytotoxicity in cancer cells. However, its modulating effect on tumor immune microenvironment remains elusive. In our experiments, compared with immunodeficient mouse mo…

The Coupling Between Tropical Meteorology, Aerosol Lifecycle, Convection, and Radiation during the Cloud, Aerosol and Monsoon Processes Philippines Experiment (CAMP2Ex) Open

Jeffrey S. Reid, H. B. Maring, Gemma Narisma, Susan C. van den Heever, Larry Di Girolamo , et al. · 2023

The NASA Cloud, Aerosol, and Monsoon Processes Philippines Experiment (CAMP 2 Ex) employed the NASA P-3, Stratton Park Engineering Company (SPEC) Learjet 35, and a host of satellites and surface sensors to characterize the coupling of aero…

Rigosertib promotes anti-tumor immunity via autophagic degradation of PD-L1 in colorectal cancer cells Open

Xinyi Zhou, Dongliang Fu, Hang Yang, Chenqin Le, Yier Lu , et al. · 2023

Rigosertib (RGS) is a benzyl styryl sulfone which exhibits impressive cytotoxicity in cancer cells. However, its modulating effect on tumor immune microenvironment remains elusive. In our experiments, compared with immunodeficient mouse mo…

Influence of Slot Combination on the Vibration of Low-Noise Asynchronous Motor Open

Haijun Feng, Yue Zhang, Changsheng Chen, Dongliang Fu, Guoping Li · 2023

The slot combination of stator and rotor plays a decisive role in the tangential force and radial force of the motor, to obtain the influence of slot combination on motor vibration and noise, taking a 55kW asynchronous motor with a maximum…

Targeting RAS mutants in malignancies: successes, failures, and reasons for hope Open

Hang Yang, Xinyi Zhou, Dongliang Fu, Chenqin Le, Jiafeng Wang , et al. · 2022

RAS genes are the most frequently mutated oncogenes and play critical roles in the development and progression of malignancies. The mutation, isoform ( KRAS , HRAS , and NRAS ), position, and type of substitution vary depending on the tiss…

LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis Open

Sixuan Wang, Jun Duan, Jiangquan Liao, Yan Wang, Xiang Xiao , et al. · 2022

H19 attenuates DCM in DM and ROS, ERS-induced cardiomyocyte apoptosis, which is associated with the activation of PI3K/AKT/mTOR signaling pathway.

Kernel Least Logarithmic Absolute Difference Algorithm Open

Dongliang Fu, Wei Gao, Wentao Shi, Qunfei Zhang · 2022

Kernel adaptive filtering (KAF) algorithms derived from the second moment of error criterion perform very well in nonlinear system identification under assumption of the Gaussian observation noise; however, they inevitably suffer from seve…

Author Index Open

Bo An, Qiang Ayub, Muhammad Saad, Luciano Bai, Guanghui Bao , et al. · 2021

Comprehensive Analysis of the Immune Effect of TGFβ1 in Colorectal Adenocarcinoma:A TGFβ1-related Prognostic Model of Tumor Microenvironment Open

Yucheng Qian, Lina Zhang, Jihang Wen, Yanxia Mei, Jingsun Wei , et al. · 2021

ColorColorectal cancer is one of the most common cancer worldwide. Recently, tumor microenvironment (TME), especially its remoulding , is thought to control the colorectal cancer genesis and progression. In this study, we use ESTIMATEscore…

Prognostic Risk Model of Immune-Related Genes in Colorectal Cancer Open

Yucheng Qian, Jingsun Wei, Wei Lu, Fangfang Sun, Maxwell Hwang , et al. · 2021

Purpose We focused on immune-related genes (IRGs) derived from transcriptomic studies, which had the potential to stratify patients’ prognosis and to establish a risk assessment model in colorectal cancer. Summary This article examined our…

Identifying Stage II Colorectal Cancer Recurrence Associated Genes by Microarray Meta-Analysis and Building Predictive Models with Machine Learning Algorithms Open

Wei Lu, Xiang Pan, Siqi Dai, Dongliang Fu, Maxwell Hwang , et al. · 2021

Background. Stage II colorectal cancer patients had heterogeneous prognosis, and patients with recurrent events had poor survival. In this study, we aimed to identify stage II colorectal cancer recurrence associated genes by microarray met…

Exosomal ANGPTL1 attenuates colorectal cancer liver metastasis by regulating Kupffer cell secretion pattern and impeding MMP9 induced vascular leakiness Open

Kai Jiang, Haiyan Chen, Yimin Fang, Liubo Chen, Chenhan Zhong , et al. · 2021

Establishment of a Risk Signature Based on m6A RNA Methylation Regulators That Predicts Poor Prognosis in Renal Cell Carcinoma Open

Jingsun Wei, Yucheng Qian, Yang Tang, Xiaoxu Ge, Kai Jiang , et al. · 2021

Collectively, the results of this study indicated that the risk model (based on two m6A RNA methylation regulators) may serve as an independent prognostic indicator of RCC, which may aid further investigation into m6A RNA modification in R…

Analysis and Optimization on Vibration Characteristics of Twin Screw Pump Open

Yan Zhong, Pu Zhou, Dongliang Fu, Zhen Lu · 2021

Based on double screw pump as the research object, the vibration of twin screw pump under different outlet conditions and different technological parameters were tested. The vibration characters of the pump under various technological para…

Efficacy of rigosertib, a small molecular RAS signaling disrupter for the treatment of <i>KRAS</i>-mutant colorectal cancer Open

Xinyi Zhou, Qian Xiao, Dongliang Fu, Haochen Zhang, Yang Tang , et al. · 2021

These data showed that targeting RAS signaling using RGS could be a therapeutic treatment for KRAS-mutant colorectal cancer patients.

Exosomal ANGPTL1 Attenuates Colorectal Cancer Liver Metastasis by Regulating Kupffer Cell Secretion Pattern and Impeding MMP9 Induced Vascular Leakiness Open

Kai Jiang, Haiyan Chen, Yimin Fang, Liubo Chen, Chenhan Zhong , et al. · 2020

Background: Angiopoietin-like protein 1 (ANGPTL1) has been proved to suppress tumor metastasis in several cancers. However, its extracellular effects on the pre-metastatic niches (PMNs) are still unclear. ANGPTL1 has been identified in exo…

An Autophagy-Related Long Noncoding RNA Signature Contributes to Poor Prognosis in Colorectal Cancer Open

Jingsun Wei, Xiaoxu Ge, Yang Tang, Yucheng Qian, Wei Lu , et al. · 2020

Purpose. Colorectal cancer is one of the most common malignant primary tumors, prone to metastasis, and associated with a poor prognosis. As autophagy is closely related to the development and treatment of colorectal cancer, we investigate…

Exosomal ANGPTL1 Attenuates CRC Liver Metastasis by Regulating Kupffer Cell Secretion Pattern and Impeding MMP9 induced vascular leakiness. Open

Kai Jiang, Haiyan Chen, Yimin Fang, Liubo Chen, Chenhan Zhong , et al. · 2020

Background: Angiopoietin-like protein 1 (ANGPTL1) has been proved to suppress tumor metastasis in several cancers. However, its extracellular effects on the pre-metastatic niches (PMNs) are still unclear. ANGPTL1 has been identified in exo…

FOLFOX treatment response prediction in metastatic or recurrent colorectal cancer patients via machine learning algorithms Open

Wei Lu, Dongliang Fu, Xiangxing Kong, Zhiheng Huang, Maxwell Hwang , et al. · 2020

Early identification of metastatic or recurrent colorectal cancer (CRC) patients who will be sensitive to FOLFOX (5‐FU, leucovorin and oxaliplatin) therapy is very important. We performed microarray meta‐analysis to identify differentially…

Fast-track multidisciplinary treatment versus conventional treatment for colorectal cancer: a multicenter, open-label randomized controlled study Open

Jun Li, Xiangxing Kong, Jiaojiao Zhou, Yongmao Song, Xuefeng Huang , et al. · 2019

Predictors and Risk Factors of Pathologic Complete Response Following Neoadjuvant Chemoradiotherapy for Rectal Cancer: A Population-Based Analysis Open

Yinuo Tan, Dongliang Fu, Dan Li, Xiangxing Kong, Kai Jiang , et al. · 2019

Background: Patients with rectal cancer who achieve pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) may have a better prognosis and may be eligible for non-operative management. The aim of this research…

Application of Fiber Reinforced PTFE Composites in the Field of Vibration Reduction Open

Zhong Yan, Feng Haijun, Dongliang Fu, Pu Zhou · 2019

In this paper, the glass fiber and carbon fiber reinforced PTFE are prepared, and the main mechanical properties and damping properties are tested. The test results show that both glass fiber and carbon fiber can decrease the tensile stren…

Predictors and risk factors of Pathologic Complete Response Following Neoadjuvant Chemoradiotherapy for Rectal Cancer Open

Yinuo Tan, Dongliang Fu, Kai Jiang, Xiangxing Kong, Ying Yuan , et al. · 2018

Background: Those rectal cancer patients who achieve a pathologic complete resonse after neoadjuvant chemoradiotheraoy may have a better prognosis and may be eligible for non-operative management. Approximately 10% to 25 % of rectal cancer…

Update on biomaterials for prevention of epidural adhesion after lumbar laminectomy Open

Huailan Wang, Wenjia Sun, Dongliang Fu, Yue‐Liang Shen, Yingying Chen , et al. · 2018

Lumbar laminectomy often results in failed back surgery syndrome. Most scholars support the three-dimensional theory of adhesion: Fibrosis surrounding the epidural tissues is based on the injured sacrospinalis behind, fibrous rings and pos…

Hybrid Photonic Cavity with Metal-Organic Framework Coatings for the Ultra-Sensitive Detection of Volatile Organic Compounds with High Immunity to Humidity Open

Jifang Tao, Xuerui Wang, Tao Sun, Hong Cai, Yuxiang Wang , et al. · 2017

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