Explanipedia

Control strategy for anode effect in aluminum electrolysis cells based on intelligent fuzzy controller Open

Dan Ding, X. Ding · 2025

In the aluminum electrolysis process, the anode effect coefficient is a crucial technical parameter that significantly impacts both the thermal equilibrium and material equilibrium of the electrolytic cell. Based on the technical principle…

Bacterial DNA‐Targeting AIE Photosensitizer for Efficient Eradication of Intracellular Bacteria and Biofilm‐Associated Infections Open

Yonghui Lv, Minyang Zhao, Zhiwen Xu, Dan Ding, Kang‐Nan Wang · 2025

Methicillin‐resistant Staphylococcus aureus (MRSA), often residing within biofilms and host cells, exhibits heightened resistance to conventional antibiotics and immune clearance, resulting in persistent and recurrent infections. Given the…

Depletion of <i>Sorcs3</i> Activates Totipotency in Mouse Embryonic Stem Cells by Modulating Key Signaling Pathways Open

Wenhao Zhang, Xiao‐Yuan Mao, Yu He, Qingshen Jia, Yiding Zhao , et al. · 2025

Totipotency represents the greatest potential to yield an entire individual alongside its associated extraembryonic tissues, albeit transiently. Nevertheless, achieving sustainable totipotent stem cells remains an intriguing yet challengin…

Towards Faithful and Controllable Personalization via Critique-Post-Edit Reinforcement Learning Open

Chenghao Zhu, Meiling Tao, Tiannan Wang, Dan Ding, Yuchen Eleanor Jiang , et al. · 2025

Faithfully personalizing large language models (LLMs) to align with individual user preferences is a critical but challenging task. While supervised fine-tuning (SFT) quickly reaches a performance plateau, standard reinforcement learning f…

Super-Resolution Microscopy Reveals Nanoscale Arrangement of PD-L1 Immune Checkpoint Open

Fulin Xing, Jianyu Yang, Fen Hu, Zhao Xie, Mingxin Chen , et al. · 2025

Six1 promotes alveolar epithelium senescence in pulmonary fibrosis through regulating Tp53 Open

Yan Fan, Zhen Tian, Hongyan Zheng, Rongman Xu, Boyu Li , et al. · 2025

Idiopathic pulmonary fibrosis (IPF) is a deadly respiratory condition distinguished by gradual fibrotic restructuring and diminishing pulmonary capacity, with cellular senescence serving as a critical factor in its pathogenesis. This study…

PersonaFeedback: A Large-scale Human-annotated Benchmark For Personalization Open

Meiling Tao, Chenghao Zhu, Dan Ding, Tiannan Wang, Yuchen Eleanor Jiang , et al. · 2025

With the rapid improvement in the general capabilities of LLMs, LLM personalization, i.e., how to build LLM systems that can generate personalized responses or services that are tailored to distinct user personas, has become an increasingl…

Correction to “Aggregation‐Mediated Photoacoustic/NIR‐II and Photodynamic Properties of pH‐Reversible Thiopyrylium Agents: A Computational and Experimental Approach” Open

Yishen Liu, Zhiyun Zhang, Xiaowen Hou, Qihang Ding, Silüe Zeng , et al. · 2025

White light-excited organic room-temperature phosphorescence for improved in vivo bioimaging Open

Lutong Zhang, Ji-Sen Li, Yifan Zhang, Wenbo Dai, Yufan Zhang , et al. · 2025

Organic phosphorescence materials offer significant advantages for bioimaging applications. However, most of these materials are excited exclusively by ultraviolet (UV) light, which poses risks to living organisms. Herein, six donor-accept…

Donor–Acceptor–Donor Structured Dyes with Balanced Photothermal Conversion Efficiency and Fluorescence Quantum Yield for Near-Infrared–II Mild-Temperature Photothermal Therapy Open

Xuan Sun, Zuyuan Zhang, Chunbai Xiang, Tianhe Qiao, Xin Wang , et al. · 2025

Effective mild-temperature photothermal therapy (MTPTT) requires photothermal agents with high photothermal conversion efficiency (PCE) and balanced fluorescence quantum yield to enable efficient tumor treatment while minimizing damage to …

Special Issue: Nanoprobes and Biomedical Imaging Open

Dan Ding, Yong Fan, Peng Huang · 2025

An Albumin‐Photosensitizer Supramolecular Assembly with Type I ROS‐Induced Multifaceted Tumor Cell Deaths for Photodynamic Immunotherapy Open

Jingtian Zhang, Di Jiao, Xinwen Qi, Yufan Zhang, Xiaoang Liu , et al. · 2025

Photodynamic therapy holds great potentials in cancer treatment, yet its effectiveness in hypoxic solid tumor is limited by the oxygen‐dependence and insufficient oxidative potential of conventional type II reactive oxygen species (ROS). H…

Exploring the efficacy and constraints of platinum nanoparticles as adjuvant therapy in silicosis management Open

G. Ban, Yuanchang Chen, Yingbing Liang, Xiaona Wang, Dan Ding , et al. · 2025

Silicosis represents a formidable occupational lung pathology precipitated by the pulmonary assimilation of respirable crystalline silica particulates. This condition engenders a cascade of cellular oxidative stress via the activation of b…

Frontispiz: An Organophosphorescence Probe with Ultralong Lifetime and Intrinsic Tissue Selectivity for Specific Tumor Imaging and Guided Tumor Surgery Open

Heqi Gao, Tingting Zhang, Yunxiang Lei, Di Jiao, Bo Yu , et al. · 2024

Research on enzymatic co-assembly nanomedicine in oral squamous cell carcinoma Open

Zhijun Xue, Yaxuan Guo, Yuanzhu Zhou, Lin Qiu, Jingrui Xin , et al. · 2024

A Membrane‐Anchoring Self‐Assembling Peptide Allows Bioorthogonal Coupling of Type‐I AIEgens for Pyroptosis‐Induced Cancer Therapy Open

Shenglu Ji, Tengwu Pan, Kaiyuan Wang, Weiqi Zai, Ruikang Jia , et al. · 2024

Enrichment of photosensitizers (PSs) on cancer cell membranes via bioorthogonal reactions is considered to be a very promising therapeutic modality. However, azide‐modified sugars‐based metabolic labeling processes usually lack targeting a…

Enhancing Root Canal Therapy with NIR‐II Semiconducting Polymer AIEgen and Low‐Concentration Sodium Hypochlorite Synergy Open

Yuanzhu Zhou, Dan Li, Xin Yue, Yang Shi, Cong Li , et al. · 2024

Despite significant efforts to eliminate bacterial biofilm within root canals, achieving effective disinfection remains challenging due to the complex anatomy and limitations of disinfectants. In this study, a second near‐infrared (NIR‐II)…

Mechanism and design of organic afterglow luminescent probes for cancer theranostics Open

Zhiyuan Gao, Yifei Zhang, Qian Liu, Dan Ding · 2024

Organic afterglow luminescent probes (OALPs), characterized by their long-lasting luminescence after irradiation (by light, ultrasound, or X-rays) cessation, are pivotal tools in autofluorescence-free optical imaging. They exhibit ultra-lo…

An Improved Algorithm for the Detection of Ventilator Associated Pneumonia Open

Dan Ding, H. P. Wang, Madeline A. DiLorenzo, Sarah Hochman, Corinne N. Thompson , et al. · 2024

Background: Ventilator associated pneumonia (VAP) is associated with significant rates of morbidity and all-cause mortality. Active VAP surveillance can identify risk factors for which targeted preventive measures can be implemented. Howev…

White-Light-Excited Organic Room-Temperature Phosphorescence for Improved In Vivo Bioimaging Open

Dan Ding, Ji-Sen Li, Lutong Zhang, Yifan Zhang, Wenbo Dai , et al. · 2024

Organic phosphorescence materials offer significant advantages for bioimaging applications. However, most of these materials are excited exclusively by ultraviolet (UV) light, which poses risks to living organisms. Herein, six donor-accept…

Imaging and Therapy of Tumors Based on Neutrophil Extracellular Traps Open

Yongwei Hao, Dalin Liu, Kaiyuan Wang, Qian Liu, Hongli Chen , et al. · 2024

Neutrophil extracellular traps (NETs) formed by neutrophils are netlike scaffolds that mainly contain DNA and a variety of granule proteins. Many stimuli can lead to the NET formation through independent molecular pathways. Clinically, the…

Voice Assistant Utilization among the Disability Community for Independent Living: A Rapid Review of Recent Evidence Open

Paola Esquivel, Kayden Gill, Mary Goldberg, S. Andrea Sundaram, Lindsey Morris , et al. · 2024

The rapid advancement and widespread adoption of voice assistance technology have shown promise in benefiting individuals with disabilities, offering increased social participation, independence, and leisure activities. However, barriers t…

Co-targeting CD47 and VEGF elicited potent anti-tumor effects in gastric cancer Open

Kaiqi Zhang, Yuan Xu, Xusheng Chang, Caili Xu, Wenjing Xue , et al. · 2024

Background CD47, serving as an intrinsic immune checkpoint, has demonstrated efficacy as an anti-tumor target in hematologic malignancies. Nevertheless, the clinical relevance of CD47 in gastric cancer and its potential as a therapeutic ta…

Exploring Control Authority Preferences in Robotic Arm Assistance for Power Wheelchair Users Open

Breelyn Kane Styler, Wei Deng, Reid Simmons, Henny Admoni, Rory A. Cooper , et al. · 2024

This paper uses mixed methods to explore the preliminary design of control authority preferences for an Assistive Robotic Manipulator (ARM). To familiarize users with an intelligent robotic arm, we perform two kitchen task iterations: one …

Preliminary Field Validity of Free-Living Energy Expenditure Estimation in Wheelchair Users with Spinal Cord Injury via Wearable Device-based Models Open

Dan Ding, Zijian Huang, Akhila Veerubhotla, James P. DeLany · 2024

Study Design Cross-sectional validation study. Objectives To develop a raw acceleration signal-based random forest (RF) model for predicting total energy expenditure (TEE) in manual wheelchair users (MWUs) and evaluate the preliminary fiel…

Rehabilitation clinicians’ use of mainstream wireless technologies in practice: a scoping review Open

Brad E. Dicianno, Angad Salh, Lindsey Morris, Yifan Xiang, Dan Ding · 2024

MWT such as apps, smartphones and tablets are being used by rehabilitation clinicians to address motor, cognitive, and speech skills, most commonly in adults. Clinicians voice a need for more education and training. Barriers and facilitato…

Nucleic acid drug and delivery techniques for disease therapy: Present situation and future prospect Open

Tianjiao Wang, Youhong Tang, Yuandong Tao, Huixia Zhou, Dan Ding · 2024

Over the two decades, RNA drugs have gradually made their way from bench to bed. Initially, RNA was not an ideal drug since RNA molecules degrade easily and have a relatively short half‐life in the circulation system. Nevertheless, the che…

Co-targeting CD47 and VEGF Elicited Potent Antitumor Effects in Gastric Cancer Open

Kaiqi Zhang, Yuan Xu, Xusheng Chang, Caili Xu, Wenjing Xue , et al. · 2023

Background CD47, serving as an intrinsic immune checkpoint, has demonstrated efficacy as an antitumor target in hematologic malignancies. Nevertheless, the clinical relevance of CD47 in gastric cancer and its potential as a therapeutic tar…

Semiconducting Polymers for Cancer Immunotherapy Open

Wen Li, Mengyun Liang, Ji Qi, Dan Ding · 2023

Inside Front Cover: In article 2300496, Ji Qi, Dan Ding, and co-workers summarize the recent advancements in semiconducting polymer (SP)-based nanomedicines for enhanced tumor immunotherapy. The cancer immunotherapies enabled by SPs with t…

Near-infrared-II photoacoustic imaging and photo-triggered synergistic treatment of thrombosis via fibrin-specific homopolymer nanoparticles Open

Jianwen Song, Xiaoying Kang, Lu Wang, Dan Ding, Deling Kong , et al. · 2023

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