Donna E. Crone
YOU?
Author Swipe
View article: Challenges and Solutions for Leave-One-Out Biosensor Design in the Context of a Rugged Fitness Landscape
Challenges and Solutions for Leave-One-Out Biosensor Design in the Context of a Rugged Fitness Landscape Open
The leave-one-out (LOO) green fluorescent protein (GFP) approach to biosensor design combines computational protein design with split protein reconstitution. LOO-GFPs reversibly fold and gain fluorescence upon encountering the target pepti…
View article: Challenges and Solutions for Leave-One-Out Biosensor Design in the Context of a Rugged Fitness Landscape
Challenges and Solutions for Leave-One-Out Biosensor Design in the Context of a Rugged Fitness Landscape Open
The Leave-One-Out (LOO) Green Fluorescent Protein (GFP) approach to biosensor design com-bines computational protein design with split protein reconstitution. LOO-GFPs reversibly fold and gain fluorescence upon encountering its target pept…
View article: Data from Aurora-A Kinase Regulates Breast Cancer–Associated Gene 1 Inhibition of Centrosome-Dependent Microtubule Nucleation
Data from Aurora-A Kinase Regulates Breast Cancer–Associated Gene 1 Inhibition of Centrosome-Dependent Microtubule Nucleation Open
Breast cancer–associated gene 1 (BRCA1) regulates the duplication and the function of centrosomes in breast cells. We have previously shown that BRCA1 ubiquitin ligase activity directly inhibits centrosome-dependent microtubule nucleation.…
View article: Data from Aurora-A Kinase Regulates Breast Cancer–Associated Gene 1 Inhibition of Centrosome-Dependent Microtubule Nucleation
Data from Aurora-A Kinase Regulates Breast Cancer–Associated Gene 1 Inhibition of Centrosome-Dependent Microtubule Nucleation Open
Breast cancer–associated gene 1 (BRCA1) regulates the duplication and the function of centrosomes in breast cells. We have previously shown that BRCA1 ubiquitin ligase activity directly inhibits centrosome-dependent microtubule nucleation.…
View article: Supplementary Figure 1 from Aurora-A Kinase Regulates Breast Cancer–Associated Gene 1 Inhibition of Centrosome-Dependent Microtubule Nucleation
Supplementary Figure 1 from Aurora-A Kinase Regulates Breast Cancer–Associated Gene 1 Inhibition of Centrosome-Dependent Microtubule Nucleation Open
Supplementary Figure 1 from Aurora-A Kinase Regulates Breast Cancer–Associated Gene 1 Inhibition of Centrosome-Dependent Microtubule Nucleation
View article: Supplementary Figure 1 from Aurora-A Kinase Regulates Breast Cancer–Associated Gene 1 Inhibition of Centrosome-Dependent Microtubule Nucleation
Supplementary Figure 1 from Aurora-A Kinase Regulates Breast Cancer–Associated Gene 1 Inhibition of Centrosome-Dependent Microtubule Nucleation Open
Supplementary Figure 1 from Aurora-A Kinase Regulates Breast Cancer–Associated Gene 1 Inhibition of Centrosome-Dependent Microtubule Nucleation
View article: Engineering a Universal Dengue Virus Vaccine using a Virus-Like Particle Scaffold
Engineering a Universal Dengue Virus Vaccine using a Virus-Like Particle Scaffold Open
The authors have withdrawn their manuscript as it was submitted and made public without the full consent of all the authors. Therefore, the authors do not wish this work to be cited as reference for the project. If you have any questions, …
View article: Mispacking and the Fitness Landscape of the Green Fluorescent Protein Chromophore Milieu
Mispacking and the Fitness Landscape of the Green Fluorescent Protein Chromophore Milieu Open
The autocatalytic maturation of the chromophore in green fluorescent protein (GFP) was thought to require the precise positioning of the side chains surrounding it in the core of the protein, many of which are strongly conserved among homo…