Doris Wagner
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View article: Wilkie\'s Syndrome with Successful Nonsurgical Conservative Treatment in a Young Man: A Case Report
Wilkie\'s Syndrome with Successful Nonsurgical Conservative Treatment in a Young Man: A Case Report Open
BACKGROUND Superior mesenteric artery syndrome, also known as Wilkie's syndrome, is a rare etiology of obstruction of the lower duodenum between the superior mesenteric artery and aorta. It often presents with unspecific abdominal pain and…
View article: Replacing middle colic artery arising from the splenic artery—an arterial variety in a patient undergoing total pancreatoduodenectomy
Replacing middle colic artery arising from the splenic artery—an arterial variety in a patient undergoing total pancreatoduodenectomy Open
Knowledge of variations in arterial vascular supply is crucial in HPB and general surgery. Although the arterial configuration of the coeliac trunk and the superior mesenteric artery had been investigated, there are still arterial branchin…
View article: Hepatectomy <i>versus</i> systemic therapy for liver-limited <i>BRAF</i> V600E-mutated colorectal liver metastases: multicentre retrospective study
Hepatectomy <i>versus</i> systemic therapy for liver-limited <i>BRAF</i> V600E-mutated colorectal liver metastases: multicentre retrospective study Open
Background To date, only two studies have compared the outcomes of patients with liver-limited BRAF V600E-mutated colorectal liver metastases (CRLMs) managed with resection versus systemic therapy alone, and these have reported contradicto…
View article: Mechanical upper bowel obstruction caused by a large trichobezoar in a young woman: A very unusual case report
Mechanical upper bowel obstruction caused by a large trichobezoar in a young woman: A very unusual case report Open
BACKGROUND Bezoars usually compile human fibers and debris. A special form of bezoar in case of psychologically altered individuals is the trichobezoar. It consists of voluntarily swallowed hair bulks and is normally removed via gastroscop…
View article: Incidence of Diabetes Mellitus and Its Impact on Outcomes in Patients Undergoing Surgical Pancreatectomy for Non-Malignant and Malignant Pancreatobiliary Diseases—A Retrospective Analysis
Incidence of Diabetes Mellitus and Its Impact on Outcomes in Patients Undergoing Surgical Pancreatectomy for Non-Malignant and Malignant Pancreatobiliary Diseases—A Retrospective Analysis Open
Diabetes mellitus (DM) is a prominent risk factor for malignant and non-malignant pancreatic diseases. Furthermore, the presence of DM predicts an unfavourable outcome in people with pancreatic cancer. This retrospective observational stud…
View article: ‘Why so high?’ Examining discrepancies between the Sr biosphere map and archaeological tooth data from the Peak District, England
‘Why so high?’ Examining discrepancies between the Sr biosphere map and archaeological tooth data from the Peak District, England Open
The analysis of 87Sr/86Sr isotope ratios in human and nonhuman tooth enamel is used worldwide for archaeological and forensic purposes to establish if an individual is likely to have grown up in the area from which their remains were excav…
View article: Treatment characteristics and outcomes of pure Acinar cell carcinoma of the pancreas – A multicentric European study on radically resected patients
Treatment characteristics and outcomes of pure Acinar cell carcinoma of the pancreas – A multicentric European study on radically resected patients Open
Radical surgery is currently the mainstay for resectable ACC, even for limited metastatic disease. Novel (neo)adjuvant treatment strategies are needed, since current systemic therapies do not result in a clear survival benefit in the perio…
View article: Combining isotope ratios for provenancing Viking Age iron artefacts in the British Isles: a pilot study
Combining isotope ratios for provenancing Viking Age iron artefacts in the British Isles: a pilot study Open
In this pilot study we investigate for the first time the possibilities of iron isotope analysis in combination with trace strontium and lead isotope analysis for provenancing iron objects believed to be from the Viking Age in the British …
View article: Demystifying BRAF Mutation Status in Colorectal Liver Metastases
Demystifying BRAF Mutation Status in Colorectal Liver Metastases Open
Objective: To investigate the clinical implications of BRAF -mutated (mut BRAF ) colorectal liver metastases (CRLMs). Background: The clinical implications of mut BRAF status in CRLMs are largely unknown. Methods: Patients undergoing resec…
View article: Applying lead (Pb) isotopes to explore mobility in humans and animals
Applying lead (Pb) isotopes to explore mobility in humans and animals Open
Lead (Pb) isotopes provide a complementary method to other provenance tools for tracking the origin and movement of humans and animals. The method is founded in the geographic distribution of Pb isotope ratios. However, unlike the Sr isoto…
View article: Gene Alterations, Mediators, and Artificial Intelligence in Colorectal Liver Metastases
Gene Alterations, Mediators, and Artificial Intelligence in Colorectal Liver Metastases Open
In this Special Issue of Cells, we seek articles that focus on the study of tumor biology in order to guide the scalpel [...]
View article: Life threatening rupture of the diaphragm after Covid 19 pneumonia: a case report
Life threatening rupture of the diaphragm after Covid 19 pneumonia: a case report Open
Background The incidence of diaphragmatic rupture is low; however, it may be life threatening. Normally caused by blunt trauma, some cases are reported after pulmonary infections with extensive coughing. Covid 19 causes pulmonary infection…
View article: Interdisciplinary Approach of Establishing PDAC Resectability: Biochemical, Radiological and NAT Regimen Prognostic Factors—Literature Review
Interdisciplinary Approach of Establishing PDAC Resectability: Biochemical, Radiological and NAT Regimen Prognostic Factors—Literature Review Open
Background and Objectives: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal tumors, with a 5-year overall survival rate of less than 10%. To date, curative surgical resection remains the only favorable option for impr…
View article: Using Artificial Intelligence to Find the Optimal Margin Width in Hepatectomy for Colorectal Cancer Liver Metastases
Using Artificial Intelligence to Find the Optimal Margin Width in Hepatectomy for Colorectal Cancer Liver Metastases Open
This cohort study used artificial intelligence-based methodologies to provide a possible resolution to the long-standing debate on optimal margin width in CRLM.
View article: MLA Style Citation Tutorial, 9th Edition
MLA Style Citation Tutorial, 9th Edition Open
Sometimes research involves contact with individuals or organizations, such as through interviews or emails.
View article: Mutant <i>KRAS</i> as a prognostic biomarker after hepatectomy for rectal cancer metastases: Does the primary disease site matter?
Mutant <i>KRAS</i> as a prognostic biomarker after hepatectomy for rectal cancer metastases: Does the primary disease site matter? Open
Background The prognostic implication of mutant KRAS (m KRA S) among patients with primary disease in the rectum remains unknown. Methods From 2000 to 2018, patients undergoing hepatectomy for colorectal liver metastases at 10 collaboratin…
View article: The optimal cut‐off values for tumor size, number of lesions, and CEA levels in patients with surgically treated colorectal cancer liver metastases: An international, multi‐institutional study
The optimal cut‐off values for tumor size, number of lesions, and CEA levels in patients with surgically treated colorectal cancer liver metastases: An international, multi‐institutional study Open
Background and Objectives Despite the long‐standing consensus on the importance of tumor size, tumor number and carcinoembryonic antigen (CEA) levels as predictors of long‐term outcomes among patients with colorectal liver metastases (CRLM…
View article: Toward an Optimized Staging System for Pancreatic Ductal Adenocarcinoma:A Clinically Interpretable, Artificial Intelligence-Based Model
Toward an Optimized Staging System for Pancreatic Ductal Adenocarcinoma:A Clinically Interpretable, Artificial Intelligence-Based Model Open
The American Joint Committee on Cancer (AJCC) eighth edition schema for pancreatic ductal adenocarcinoma treats T and N stage as independent factors and uses positive lymph nodes (PLNs) to define N stage, despite data favoring lymph node r…
View article: The “critical view of safety (CVS)” cannot be applied—What to do? Strategies to avoid bile duct injuries
The “critical view of safety (CVS)” cannot be applied—What to do? Strategies to avoid bile duct injuries Open
Summary Laparoscopic cholecystectomy has become the standard procedure worldwide since the early 1990s for those patients whose gallbladder has to be removed as part of their underlying disease (NIH Consensus Statement 1992). The most comm…
View article: Effects of Testosterone Replacement in Hypogonadal Heart Transplanted Men
Effects of Testosterone Replacement in Hypogonadal Heart Transplanted Men Open
Context: Hypogonadism is common in cardiac transplant patients and exerts negative effects on bone, but also libido and quality of life.
View article: Association of <i>BRAF</i> Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer
Association of <i>BRAF</i> Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer Open
The presence of the V600E BRAF mutation was associated with worse prognosis and increased risk of recurrence. The V600E mutation was not only a stronger prognostic factor than KRAS but also was the strongest prognostic determinant in the o…
View article: Double KRAS and BRAF Mutations in Surgically Treated Colorectal Cancer Liver Metastases: An International, Multi-institutional Case Series
Double KRAS and BRAF Mutations in Surgically Treated Colorectal Cancer Liver Metastases: An International, Multi-institutional Case Series Open
The present case series suggests that the incidence of concomitant KRAS/BRAF mutations in surgical cohorts may be higher than previously hypothesized, and associated with more variable survival outcomes than expected.
View article: Low 25-OH-vitamin D levels reflect hepatic dysfunction and are associated with mortality in patients with liver cirrhosis
Low 25-OH-vitamin D levels reflect hepatic dysfunction and are associated with mortality in patients with liver cirrhosis Open
Vitamin D levels progressively decrease in more advanced Child stages and in patients with increasing HVPG. Vitamin D deficiency might be a valuable predictor of mortality in cirrhosis.
View article: Vascular calcification - Impact of PRRG1-4
Vascular calcification - Impact of PRRG1-4 Open
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
View article: Calcification in the vessel wall: impact of vitamin K dependent proteins
Calcification in the vessel wall: impact of vitamin K dependent proteins Open
Searchable abstracts of presentations at key conferences on calcified tissues ISSN 2052-1219 (online)