Dorit Rennspiess
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View article: Clinicopathological Study on Morphological Subtypes of Hepatocellular Carcinoma: A Single Tertiary Referral Center Experience
Clinicopathological Study on Morphological Subtypes of Hepatocellular Carcinoma: A Single Tertiary Referral Center Experience Open
Aim We aimed to analyze hepatocellular carcinoma (HCC) morphological subtypes characterized according to the WHO classification and the International Collaboration on Cancer Reporting (ICCR) recommendations, and their prognostic features i…
View article: Mapping of Human Polyomavirus in Renal Cell Carcinoma Tissues
Mapping of Human Polyomavirus in Renal Cell Carcinoma Tissues Open
Worldwide, the incidence of renal cell carcinoma (RCC) is rising, accounting for approximately 2% of all cancer diagnoses and deaths. The etiology of RCC is still obscure. Here, we assessed the presence of HPyVs in paraffin-embedded tissue…
View article: Bovine Meat and Milk Factor-like Sequences Are Frequently Detected in Renal Cell Carcinoma Tissues
Bovine Meat and Milk Factor-like Sequences Are Frequently Detected in Renal Cell Carcinoma Tissues Open
Previous studies have indicated a potential role of diet in the pathogenesis of renal cell carcinoma (RCC). Recently, circular bovine meat and milk factor (BMMF) DNAs have been identified in peritumoral tissues of human colon and breast ca…
View article: Intestinal smooth muscle aberrations in pancreatic cancer patients with sarcopenia
Intestinal smooth muscle aberrations in pancreatic cancer patients with sarcopenia Open
Background Cancer cachexia is characterized by impaired function of skeletal and cardiac muscle. Smooth muscle is abundantly present in the body and critical for the function of the gastrointestinal tract. Given the frequently reported gas…
View article: High Prevalence of Human Polyomavirus 7 in Cholangiocarcinomas and Adjacent Peritumoral Hepatocytes: Preliminary Findings
High Prevalence of Human Polyomavirus 7 in Cholangiocarcinomas and Adjacent Peritumoral Hepatocytes: Preliminary Findings Open
Cholangiocarcinoma (CCA) is a rare biliary-duct malignancy with poor prognosis. Recently, the presence of the human polyomavirus 6 (HPyV6) has been reported in the bile of diverse hepatobiliary diseases, particularly in the bile of CCA pat…
View article: Low prevalence of Merkel cell polyomavirus in human epithelial thymic tumors
Low prevalence of Merkel cell polyomavirus in human epithelial thymic tumors Open
Background The etiology of thymic epithelial tumors is unknown. Murine polyomavirus strain PTA has been shown to induce thymomas in mice. Recently, using diverse molecular techniques, we reported the presence of human polyomavirus 7 (HPyV7…
View article: Characterization of the thymus in Lrp4 myasthenia gravis: Four cases
Characterization of the thymus in Lrp4 myasthenia gravis: Four cases Open
Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction. Most patients have pathogenic autoantibodies against the acetylcholine receptor (AChR). In the last years a novel subpopulation of MG patients has been describe…
View article: Neuroendocrine Key Regulator Gene Expression in Merkel Cell Carcinoma
Neuroendocrine Key Regulator Gene Expression in Merkel Cell Carcinoma Open
View article: Molecular profiling of Spitz nevi identified by digital RNA counting
Molecular profiling of Spitz nevi identified by digital RNA counting Open
The molecular properties of benign melanocytic lesions are poorly understood. Only a few studies have been carried out on specific nevi subtypes, including common nevocellular nevi (NCN) or Spitz nevi (SN). Genomic alterations in melanoma-…
View article: Acetone clearance of mesocolic or mesorectal fat increases lymph node yield and may improve detection of high‐risk Stage II colorectal cancer patients
Acetone clearance of mesocolic or mesorectal fat increases lymph node yield and may improve detection of high‐risk Stage II colorectal cancer patients Open
Aim Lymph node ( LN ) status is key to determining the need for adjuvant therapy in colorectal cancer (CRC) and for disease which has progressed to Stage II (T3–T4, N0, M0). A yield of fewer than 12 LN s is considered a risk factor similar…
View article: Phosphatidylinositol 3-kinase p110δ expression in Merkel cell carcinoma
Phosphatidylinositol 3-kinase p110δ expression in Merkel cell carcinoma Open
The prognosis of stage III/IV Merkel cell carcinoma (MCC) is very poor. The Phosphatidylinositol 3-kinase p110δ specific inhibitor idelalisib has recently been reported to induce complete clinical remission in a stage IV MCC patient. Here …
View article: USCAP 2018 Abstracts: Dermatopathology(524–585)
USCAP 2018 Abstracts: Dermatopathology(524–585) Open
Background: Melanoma disease burden is confounded by its propensity for mimicry of many cancers histologically.Afflicted cancer patients in our setting present with advanced diseases.Thus, accurate diagnosis is mandatory for the treatment …
View article: Detection of Merkel Cell Polyomavirus in Seborrheic Keratosis
Detection of Merkel Cell Polyomavirus in Seborrheic Keratosis Open
Seborrheic keratosis (SK) is the most common benign cutaneous neoplasm. A subset shows increased p16 expression. Since SK shares several features with verruca vulgaris, e.g., increased p16 expression, human papillomaviruses (HPV) have been…
View article: Reviewing the current evidence supporting early B-cells as the cellular origin of Merkel cell carcinoma
Reviewing the current evidence supporting early B-cells as the cellular origin of Merkel cell carcinoma Open
View article: Merkelzellkarzinom: kutane Manifestation einer hochmalignen Prä-/pro-B-Zell-Neoplasie?
Merkelzellkarzinom: kutane Manifestation einer hochmalignen Prä-/pro-B-Zell-Neoplasie? Open
View article: Merkel cell carcinoma: cutaneous manifestation of a highly malignant pre-/pro-B cell neoplasia?
Merkel cell carcinoma: cutaneous manifestation of a highly malignant pre-/pro-B cell neoplasia? Open
View article: Frequent detection of human polyomavirus 6 in keratoacanthomas
Frequent detection of human polyomavirus 6 in keratoacanthomas Open
The high frequency of HPyV6 DNA in 42.3 % of KA possibly points to a role for HPyV6 in the etiopathogenesis of KAs. Although the detection rate of HPyV6 DNA in BCCs and TBs is within the previously reported detection range in normal skin, …
View article: Detection of Human Polyomavirus 7 in Human Thymic Epithelial Tumors
Detection of Human Polyomavirus 7 in Human Thymic Epithelial Tumors Open