Dorothea Strobach
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View article: Multicenter Renal Pharmacist Group—Pharmaceutical Care for Patients with Renal Impairment at Four Non-University Hospitals in Germany
Multicenter Renal Pharmacist Group—Pharmaceutical Care for Patients with Renal Impairment at Four Non-University Hospitals in Germany Open
Background: The project ‘Multicenter Renal Pharmacist Group—Implementation of Pharmaceutical Care for Patients with Renal Impairment at four Non-University Hospitals in Germany’ started in the beginning of 2020 with the goal to establish h…
View article: Concept of Modeling Pharmacist-Led Medication Reviews in Clinical Setting: A Knowledge Graph-Based Approach
Concept of Modeling Pharmacist-Led Medication Reviews in Clinical Setting: A Knowledge Graph-Based Approach Open
Medication reviews (MR) are essential for optimizing patient care and drug therapy safety. This study examined clinical pharmacists’ decision-making during MRs. Five clinical pharmacists from university hospitals in Germany conducted inter…
View article: Correction: Anticholinergic Exposure, Drug Dose and Postoperative Delirium: Comparison of Dose-Related and Non-Dose-Related Anticholinergic Burden Scores in a Retrospective Cohort Study of Older Orthopaedic and Trauma Surgery Patients
Correction: Anticholinergic Exposure, Drug Dose and Postoperative Delirium: Comparison of Dose-Related and Non-Dose-Related Anticholinergic Burden Scores in a Retrospective Cohort Study of Older Orthopaedic and Trauma Surgery Patients Open
View article: Risk Stratification of QTc Prolongations in Hospitalized Cardiology and Gastroenterology Patients Using the Tisdale Score—A Retrospective Analysis
Risk Stratification of QTc Prolongations in Hospitalized Cardiology and Gastroenterology Patients Using the Tisdale Score—A Retrospective Analysis Open
Background/Objectives: QTc prolongation can result in lethal arrhythmia. Risk scores like the Tisdale score can be used for risk stratification for targeted pharmaceutical interventions. However, the practical usability across different me…
View article: Anticholinergic Exposure, Drug Dose and Postoperative Delirium: Comparison of Dose-Related and Non-Dose-Related Anticholinergic Burden Scores in a Retrospective Cohort Study of Older Orthopaedic and Trauma Surgery Patients
Anticholinergic Exposure, Drug Dose and Postoperative Delirium: Comparison of Dose-Related and Non-Dose-Related Anticholinergic Burden Scores in a Retrospective Cohort Study of Older Orthopaedic and Trauma Surgery Patients Open
Both dose-related and non-dose-related AC burden scores have limited sensitivity and modest PPV for screening a patient's medication for POD. However, given the additional effort required for dose consideration, the non-dose-related GerACB…
View article: Determining sensitivity and specificity of risk scores for QTc interval prolongation in hemato-oncology patients prescribed systemic antifungal therapy: a retrospective cross-sectional study
Determining sensitivity and specificity of risk scores for QTc interval prolongation in hemato-oncology patients prescribed systemic antifungal therapy: a retrospective cross-sectional study Open
View article: Factors Determining Quality of Drug Information by Hospital Pharmacies—Results from Five-Year Annual Quality Assessment
Factors Determining Quality of Drug Information by Hospital Pharmacies—Results from Five-Year Annual Quality Assessment Open
Drug information (DI) provided by hospital pharmacies aims to promote rational and safe drug therapy. While quality assessment for this task is recommended, more knowledge on the factors determining the quality is needed. We aimed to evalu…
View article: INTERPOLAR – prospektive, interventionelle Studien im Rahmen der Medizininformatik-Initiative zur Verbesserung der Arzneimitteltherapiesicherheit in der Krankenversorgung
INTERPOLAR – prospektive, interventionelle Studien im Rahmen der Medizininformatik-Initiative zur Verbesserung der Arzneimitteltherapiesicherheit in der Krankenversorgung Open
View article: Development and validation of a new drug-focused predictive risk score for postoperative delirium in orthopaedic and trauma surgery patients
Development and validation of a new drug-focused predictive risk score for postoperative delirium in orthopaedic and trauma surgery patients Open
Background Postoperative delirium (POD) is the most common complication following surgery in elderly patients. During pharmacist-led medication reconciliation (PhMR), a predictive risk score considering delirium risk-increasing drugs and o…
View article: Hepatic Impairment as a Risk Factor for Drug Safety: Suitability and Comparison of Four Liver Scores as Screening Tools
Hepatic Impairment as a Risk Factor for Drug Safety: Suitability and Comparison of Four Liver Scores as Screening Tools Open
Hepatic impairment (HI) influences the pharmacokinetics and pharmacodynamics of drugs and represents an important risk factor for drug safety. A reliable screening tool for HI identification at hospital admission by pharmacists would be de…
View article: The Characterization of Non-oncologic Chronic Drug Therapy in Bladder Cancer Patients and the Impact on Recurrence-Free and Cancer-Specific Survival: A Prospective Study
The Characterization of Non-oncologic Chronic Drug Therapy in Bladder Cancer Patients and the Impact on Recurrence-Free and Cancer-Specific Survival: A Prospective Study Open
We aimed to characterize non-oncologic chronic drug therapy of bladder cancer (BC) patients and evaluate a possible impact on recurrence-free (RFS) and cancer-specific survival (CSS). Patients with a first diagnosis (FD) of BC or radical c…
View article: Biologically Based Complementary and Alternative Medicine Use in Breast Cancer Patients and Possible Drug-Drug Interactions
Biologically Based Complementary and Alternative Medicine Use in Breast Cancer Patients and Possible Drug-Drug Interactions Open
Purpose: Biologically based complementary and alternative medicine (BB-CAM) is gaining importance. Cancer patients in particular are at risk of interactions between the prescribed medications (intravenous or oral anticancer therapy, concom…
View article: A new medication-based prediction score for postoperative delirium in surgical patients: Development and proof of feasibility in a retrospective patient cohort.
A new medication-based prediction score for postoperative delirium in surgical patients: Development and proof of feasibility in a retrospective patient cohort. Open
Structured risk screening for postoperative delirium (POD) considering prehospital medication is not established. We aimed to develop a POD-risk prediction score based on known risk factors and delirium-risk increasing drugs to be used by …
View article: Benefit of medication reviews by renal pharmacists in the setting of a computerized physician order entry system with clinical decision support
Benefit of medication reviews by renal pharmacists in the setting of a computerized physician order entry system with clinical decision support Open
In the setting of prescribing in a CPOE-CDS-system, that provides physicians with advice for drug or dose adaption, the pharmacist-led medication reviews still identified DRP in orthopaedic and trauma patients with RI. A RPCS forwarding re…
View article: 4CPS-209 Benefit of medication reviews by a renal pharmacist in the setting of a computerised physician order entry system
4CPS-209 Benefit of medication reviews by a renal pharmacist in the setting of a computerised physician order entry system Open
Background and importance A 'renal pharmacist consultant service' (RPCS) reviewing patients with renal impairment (RI) for drug-related problems (DRP) can foster patient safety.1 However, the benefit of this service in the new s…
View article: Retrospective evaluation of the impact of non-oncologic chronic drug therapy on the survival in patients with bladder cancer
Retrospective evaluation of the impact of non-oncologic chronic drug therapy on the survival in patients with bladder cancer Open
View article: Management of drug-disease interactions: a best practice from the Netherlands
Management of drug-disease interactions: a best practice from the Netherlands Open
View article: Implementation of a renal pharmacist consultant service — Information sharing in paper versus digital form
Implementation of a renal pharmacist consultant service — Information sharing in paper versus digital form Open
A RPCS identifies patients at risk for rDRP and significantly increases appropriate prescribing by physicians. In our hospital (no electronic order entry, electronic chart or ward pharmacists), consultations in paper form seem to be superi…
View article: Assessing the quality of drug information provided by hospital pharmacies using a fictitious enquiry and simulated real-life conditions
Assessing the quality of drug information provided by hospital pharmacies using a fictitious enquiry and simulated real-life conditions Open
OBJECTIVES: Guidelines for drug information (DI) provided by hospital pharmacists call for quality assurance procedures; however, no method of evaluation is internationally agreed on. The procedure should be feasible, reproducible and repr…
View article: Correct use of non-indexed eGFR for drug dosing and renal drug-related problems at hospital admission
Correct use of non-indexed eGFR for drug dosing and renal drug-related problems at hospital admission Open
View article: Accuracy of freely available online GFR calculators using the CKD-EPI equation
Accuracy of freely available online GFR calculators using the CKD-EPI equation Open
Purpose Estimated glomerular filtration rate (eGFR) as calculated by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation is used for detection of chronic kidney disease and drug dose adjustment. The purpose of the pres…
View article: Transfer of knowledge into clinical practice: an ongoing problem. An example of adverse drug reactions impairing male fertility
Transfer of knowledge into clinical practice: an ongoing problem. An example of adverse drug reactions impairing male fertility Open
There is still a gap between the information available on the desired and adverse effects of drugs, and the use of these drugs in clinical practice. We present an enquiry from a patient with a wish to father a child. He asked if carbamazep…