Dorry L. Segev
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View article: Neighborhood Factors, Air Pollution, and Mortality Among Kidney Failure Patients: Exploring Differences by Race and Ethnicity
Neighborhood Factors, Air Pollution, and Mortality Among Kidney Failure Patients: Exploring Differences by Race and Ethnicity Open
View article: Environmental and social injustices impact dementia risk among older adults with end-stage kidney disease: a national registry study
Environmental and social injustices impact dementia risk among older adults with end-stage kidney disease: a national registry study Open
View article: A Metabolomics Approach to Identify Metabolites Associated with Uremic Symptoms in Patients Receiving Maintenance Hemodialysis
A Metabolomics Approach to Identify Metabolites Associated with Uremic Symptoms in Patients Receiving Maintenance Hemodialysis Open
Background: The specific toxins causing uremic symptoms (nausea, vomiting, pruritus, fatigue, difficulty concentrating and pain) in kidney failure remain unknown. We used untargeted metabolomics to identify plasma metabolites associated wi…
View article: Patient and Stakeholder Collaborative Research: Development of a Community Advisory Board for Nephrology and Transplantation Studies
Patient and Stakeholder Collaborative Research: Development of a Community Advisory Board for Nephrology and Transplantation Studies Open
Community input enhances the impact of research. Yet, there are challenges when eliciting community perspectives in nephrology/transplant research: recruitment of patients across a wide spectrum of familiarity with kidney disease; a lack o…
View article: The Synergistic Impact of Air Pollution and Residential Neighborhood Segregation on Post–Kidney Transplant Mortality
The Synergistic Impact of Air Pollution and Residential Neighborhood Segregation on Post–Kidney Transplant Mortality Open
View article: A National Survey of Surgical Chairs to Investigate the Role of Diversity, Equity, and Inclusion Vice Chairs in Departments of Surgery
A National Survey of Surgical Chairs to Investigate the Role of Diversity, Equity, and Inclusion Vice Chairs in Departments of Surgery Open
Objective: The aim is to identify surgical department chairs’ perspectives on the role of Vice Chairs for Diversity, Equity, and Inclusion (DEI VCs). Background: The role of DEI VCs has become increasingly common in departments of surgery.…
View article: Corrigendum to “Identifying when racial and ethnic disparities arise along the continuum of transplant care: a national registry study”- The Lancet Regional Health—Americas October 2024; Volume 38: 100895; DOI: 10.1016/j.lana.2024.100895
Corrigendum to “Identifying when racial and ethnic disparities arise along the continuum of transplant care: a national registry study”- The Lancet Regional Health—Americas October 2024; Volume 38: 100895; DOI: 10.1016/j.lana.2024.100895 Open
[This corrects the article DOI: 10.1016/j.lana.2024.100895.].
View article: Intradialytic Cognitive and Aerobic Exercise Training to Preserve Cognitive Function: IMPCT, A Multi-Dialysis Center 2x2 Factorial Block-Randomized Controlled Trial
Intradialytic Cognitive and Aerobic Exercise Training to Preserve Cognitive Function: IMPCT, A Multi-Dialysis Center 2x2 Factorial Block-Randomized Controlled Trial Open
Introduction: Patients with end-stage kidney disease (ESKD) develop cognitive impairment due to comorbidities and dialysis dependence. Among community-dwelling older adults, cognitive (CT) and exercise training (ET) are promising intervent…
View article: Kaposi Sarcoma–Associated Herpesvirus Risk and Disease in Kidney Donors and Transplant Recipients With Human Immunodeficiency Virus in the United States
Kaposi Sarcoma–Associated Herpesvirus Risk and Disease in Kidney Donors and Transplant Recipients With Human Immunodeficiency Virus in the United States Open
Background Due to high prevalence of Kaposi sarcoma–associated herpesvirus (KSHV) among people with human immunodeficiency virus (HIV), KSHV-associated disease (KAD) may be increased after kidney transplantation from donors with HIV (HIV D…
View article: Early Steps of the Kidney Transplant Process: What Are the Experiences of Dialysis Social Workers?
Early Steps of the Kidney Transplant Process: What Are the Experiences of Dialysis Social Workers? Open
Introduction Dialysis social workers (DSWs) educate and advocate for end‐stage kidney disease (ESKD) patients during the kidney transplantation (KT) process. However, little is known about the barriers DSWs face as they help patients get w…
View article: <i>APOL1</i> genotype and patient outcomes in US and South African transplant recipients with HIV who received kidneys from donors with HIV
<i>APOL1</i> genotype and patient outcomes in US and South African transplant recipients with HIV who received kidneys from donors with HIV Open
Importance Lower kidney allograft survival has been demonstrated in kidney transplant recipients (KTR) without HIV whose donors have two apolipoprotein L1 ( APOL1 ) renal risk variants (RRV). The effects of APOL1 RRV on kidney transplant o…
View article: Into Adulthood: Assessing Parental Perceptions and Concerns for Pediatric Heart Transplant Recipients Around the Transition Into Adult Care
Into Adulthood: Assessing Parental Perceptions and Concerns for Pediatric Heart Transplant Recipients Around the Transition Into Adult Care Open
Background Parents of pediatric heart transplant (HTx) recipients have a unique perspective on the challenges associated with the transition into adult care networks. We sought to assess parental perceptions of the challenges pediatric HTx…
View article: A third COVID-19 vaccine dose in kidney transplant recipients induces antibody response to vaccine and Omicron variants but shows limited Ig subclass switching
A third COVID-19 vaccine dose in kidney transplant recipients induces antibody response to vaccine and Omicron variants but shows limited Ig subclass switching Open
Solid organ transplant recipients (SOTRs) suffer more frequent and more severe infections due to their compromised immune responses resulting from immunosuppressive treatments designed to prevent organ rejection. Pharmacological immunosupp…
View article: Medical large language models are vulnerable to data-poisoning attacks
Medical large language models are vulnerable to data-poisoning attacks Open
The adoption of large language models (LLMs) in healthcare demands a careful analysis of their potential to spread false medical knowledge. Because LLMs ingest massive volumes of data from the open Internet during training, they are potent…
View article: Immunobridging Trials: An Important Tool to Protect Vulnerable and Immunocompromised Patients Against Evolving Pathogens
Immunobridging Trials: An Important Tool to Protect Vulnerable and Immunocompromised Patients Against Evolving Pathogens Open
Safeguarding patients from emerging infectious diseases demands strategies that prioritise patient well-being and protection. Immunobridging is an established trial methodology which has been increasingly employed to ensure patient protect…
View article: Higher abdominal fat area associates with lower donor kidney function before and after living kidney donation
Higher abdominal fat area associates with lower donor kidney function before and after living kidney donation Open
View article: Lung transplant outcomes for recipients with alpha-1 antitrypsin deficiency, by use of alpha-1 antitrypsin augmentation therapy
Lung transplant outcomes for recipients with alpha-1 antitrypsin deficiency, by use of alpha-1 antitrypsin augmentation therapy Open
View article: Safety of Kidney Transplantation from Donors with HIV
Safety of Kidney Transplantation from Donors with HIV Open
The primary objective of this study is to determine if an HIV-infected deceased kidney donor (HIVD+) transplant is safe with regard to major transplant-related and HIV-related complications.
View article: Identifying when racial and ethnic disparities arise along the continuum of transplant care: a national registry study
Identifying when racial and ethnic disparities arise along the continuum of transplant care: a national registry study Open
View article: Dietary Restriction, Socioeconomic Factors, Access to Kidney Transplantation, and Waitlist Mortality
Dietary Restriction, Socioeconomic Factors, Access to Kidney Transplantation, and Waitlist Mortality Open
Introduction Dietary restrictions for patients with end‐stage kidney disease (ESKD) are burdensome. Kidney transplantation (KT) candidates who lack neighborhood resources and are burdened by dietary restrictions may have decreased access t…
View article: Association of Pre–Lung Transplant Opioid Use With Posttransplant Opioid Use and Outcomes
Association of Pre–Lung Transplant Opioid Use With Posttransplant Opioid Use and Outcomes Open
Pretransplantation OU was the strongest independent risk factor for posttransplantation OU and was associated with greater morbidity and mortality. Reducing pretransplantation and posttransplantation OU could benefit LT recipients and shou…
View article: A Third COVID-19 Vaccine Dose in Kidney Transplant Recipients Induces Antibody Response to Vaccine and Omicron Variants but Shows Limited Ig Subclass Switching
A Third COVID-19 Vaccine Dose in Kidney Transplant Recipients Induces Antibody Response to Vaccine and Omicron Variants but Shows Limited Ig Subclass Switching Open
Solid organ transplant recipients (SOTRs) suffer more frequent and more severe infections due to their compromised immune responses resulting from immunosuppressive treatments designed to prevent organ rejection. Pharmacological immunosupp…
View article: Regional Disparities in Kidney Transplant Allocation in Brazil: A Retrospective Cohort Study
Regional Disparities in Kidney Transplant Allocation in Brazil: A Retrospective Cohort Study Open
Background Brazil has a large public transplant program, but it remains unclear if the kidney waitlist criteria effectively allocate organs. This study aimed to investigate whether gender, ethnicity, clinical characteristics, and Brazilian…
View article: Thirty-Year Trends in Perioperative Mortality Risk for Living Kidney Donors
Thirty-Year Trends in Perioperative Mortality Risk for Living Kidney Donors Open
This study uses a national registry study to characterize temporal trends in perioperative mortality in donors and risk factors associated with this event.
View article: Patient Perspectives on the Use of Aging Metrics for Kidney Transplant Decision-Making
Patient Perspectives on the Use of Aging Metrics for Kidney Transplant Decision-Making Open
Introduction Frailty and cognitive function are often measured during kidney transplant evaluation. However, patient perspectives on the ethical considerations of this practice are unclear. Research Question What are patient perspectives o…
View article: Lung Transplantation Outcomes and Peritransplant Sirolimus Use in Lymphangioleiomyomatosis
Lung Transplantation Outcomes and Peritransplant Sirolimus Use in Lymphangioleiomyomatosis Open
View article: Rapid Wane and Recovery of XBB Sublineage Neutralization After Sequential Omicron-based Vaccination in Solid Organ Transplant Recipients
Rapid Wane and Recovery of XBB Sublineage Neutralization After Sequential Omicron-based Vaccination in Solid Organ Transplant Recipients Open
Durability of variant neutralization in solid organ transplant recipients following Omicron-containing boosters is unknown. We report wane in XBB.1.5 neutralization by 3 months following a first bivalent booster, improved by a second boost…
View article: Components of Residential Neighborhood Deprivation and Their Impact on the Likelihood of Live‐Donor and Preemptive Kidney Transplantation
Components of Residential Neighborhood Deprivation and Their Impact on the Likelihood of Live‐Donor and Preemptive Kidney Transplantation Open
Introduction Adults residing in deprived neighborhoods face various socioeconomic stressors, hindering their likelihood of receiving live‐donor kidney transplantation (LDKT) and preemptive kidney transplantation (KT). We quantified the ass…
View article: Medical Distrust Among Kidney Transplant Candidates
Medical Distrust Among Kidney Transplant Candidates Open
Background Medical distrust may hinder kidney transplantation (KT) access. Among KT candidates evaluated for waitlisting, we identified factors associated with high distrust levels and quantified their association with waitlisting. Methods…
View article: A Metabolomics Approach to Identify Metabolites Associated With Mortality in Patients Receiving Maintenance Hemodialysis
A Metabolomics Approach to Identify Metabolites Associated With Mortality in Patients Receiving Maintenance Hemodialysis Open